Short-segment heart sound classification using an ensemble of deep convolutional neural networks

This paper proposes a framework based on deep convolutional neural networks (CNNs) for automatic heart sound classification using short-segments of individual heart beats. We design a 1D-CNN that directly learns features from raw heart-sound signals, and a 2D-CNN that takes inputs of two- dimensional time-frequency feature maps based on Mel-frequency cepstral coefficients (MFCC). We further develop a time-frequency CNN ensemble (TF-ECNN) combining the 1D-CNN and 2D-CNN based on score-level fusion of the class probabilities. On the large PhysioNet CinC challenge 2016 database, the proposed CNN models outperformed traditional classifiers based on support vector machine and hidden Markov models with various hand-crafted time- and frequency-domain features. Best classification scores with 89.22% accuracy and 89.94% sensitivity were achieved by the ECNN, and 91.55% specificity and 88.82% modified accuracy by the 2D-CNN alone on the test set.Comment: 8 pages, 1 figure, conferenc

Precision medicine and artificial intelligence : a pilot study on deep learning for hypoglycemic events detection based on ECG

Tracking the fluctuations in blood glucose levels is important for healthy subjects and crucial diabetic patients. Tight glucose monitoring reduces the risk of hypoglycemia, which can result in a series of complications, especially in diabetic patients, such as confusion, irritability, seizure and can even be fatal in specific conditions. Hypoglycemia affects the electrophysiology of the heart. However, due to strong inter-subject heterogeneity, previous studies based on a cohort of subjects failed to deploy electrocardiogram (ECG)-based hypoglycemic detection systems reliably. The current study used personalised medicine approach and Artificial Intelligence (AI) to automatically detect nocturnal hypoglycemia using a few heartbeats of raw ECG signal recorded with non-invasive, wearable devices, in healthy individuals, monitored 24 hours for 14 consecutive days. Additionally, we present a visualisation method enabling clinicians to visualise which part of the ECG signal (e.g., T-wave, ST-interval) is significantly associated with the hypoglycemic event in each subject, overcoming the intelligibility problem of deep-learning methods. These results advance the feasibility of a real-time, non-invasive hypoglycemia alarming system using short excerpts of ECG signal

Precision medicine and artificial intelligence : a pilot study on deep learning for hypoglycemic events detection based on ECG

Tracking the fluctuations in blood glucose levels is important for healthy subjects and crucial diabetic patients. Tight glucose monitoring reduces the risk of hypoglycemia, which can result in a series of complications, especially in diabetic patients, such as confusion, irritability, seizure and can even be fatal in specific conditions. Hypoglycemia affects the electrophysiology of the heart. However, due to strong inter-subject heterogeneity, previous studies based on a cohort of subjects failed to deploy electrocardiogram (ECG)-based hypoglycemic detection systems reliably. The current study used personalised medicine approach and Artificial Intelligence (AI) to automatically detect nocturnal hypoglycemia using a few heartbeats of raw ECG signal recorded with non-invasive, wearable devices, in healthy individuals, monitored 24 hours for 14 consecutive days. Additionally, we present a visualisation method enabling clinicians to visualise which part of the ECG signal (e.g., T-wave, ST-interval) is significantly associated with the hypoglycemic event in each subject, overcoming the intelligibility problem of deep-learning methods. These results advance the feasibility of a real-time, non-invasive hypoglycemia alarming system using short excerpts of ECG signal

Fast and accurate algorithm for ECG authentication using residual depthwise separable convolutional neural networks

The electrocardiogram (ECG) is relatively easy to acquire and has been used for reliable biometric authentication. Despite growing interest in ECG authentication, there are still two main problems that need to be tackled, i.e., the accuracy and processing speed. Therefore, this paper proposed a fast and accurate ECG authentication utilizing only two stages, i.e., ECG beat detection and classification. By minimizing time-consuming ECG signal pre-processing and feature extraction, our proposed two-stage algorithm can authenticate the ECG signal around 660 μs. Hamilton’s method was used for ECG beat detection, while the Residual Depthwise Separable Convolutional Neural Network (RDSCNN) algorithm was used for classification. It was found that between six and eight ECG beats were required for authentication of different databases. Results showed that our proposed algorithm achieved 100% accuracy when evaluated with 48 patients in the MIT-BIH database and 90 people in the ECG ID database. These results showed that our proposed algorithm outperformed other state-of-the-art methods

A Multitier Deep Learning Model for Arrhythmia Detection

Electrocardiograph (ECG) is employed as a primary tool for diagnosing cardiovascular diseases (CVD) in the hospital, which often helps in the early detection of such ailments. ECG signals provide a framework to probe the underlying properties and enhance the initial diagnosis obtained via traditional tools and patient-doctor dialogues. It provides cardiologists with inferences regarding more serious cases. Notwithstanding its proven utility, deciphering large datasets to determine appropriate information remains a challenge in ECG-based CVD diagnosis and treatment. Our study presents a deep neural network (DNN) strategy to ameliorate the aforementioned difficulties. Our strategy consists of a learning stage where classification accuracy is improved via a robust feature extraction. This is followed using a genetic algorithm (GA) process to aggregate the best combination of feature extraction and classification. The MIT-BIH Arrhythmia was employed in the validation to identify five arrhythmia categories based on the association for the advancement of medical instrumentation (AAMI) standard. The performance of the proposed technique alongside state-of-the-art in the area shows an increase of 0.94 and 0.953 in terms of average accuracy and F1 score, respectively. The proposed model could serve as an analytic module to alert users and/or medical experts when anomalies are detected in the acquired ECG data in a smart healthcare framework

Algorithms for automated diagnosis of cardiovascular diseases based on ECG data: A comprehensive systematic review

The prevalence of cardiovascular diseases is increasing around the world. However, the technology is evolving and can be monitored with low-cost sensors anywhere at any time. This subject is being researched, and different methods can automatically identify these diseases, helping patients and healthcare professionals with the treatments. This paper presents a systematic review of disease identification, classification, and recognition with ECG sensors. The review was focused on studies published between 2017 and 2022 in different scientific databases, including PubMed Central, Springer, Elsevier, Multidisciplinary Digital Publishing Institute (MDPI), IEEE Xplore, and Frontiers. It results in the quantitative and qualitative analysis of 103 scientific papers. The study demonstrated that different datasets are available online with data related to various diseases. Several ML/DP-based models were identified in the research, where Convolutional Neural Network and Support Vector Machine were the most applied algorithms. This review can allow us to identify the techniques that can be used in a system that promotes the patient’s autonomy.N/

Personalized Monitoring and Advance Warning System for Cardiac Arrhythmias

Each year more than 7 million people die from cardiac arrhythmias. Yet no robust solution exists today to detect such heart anomalies right at the moment they occur. The purpose of this study was to design a personalized health monitoring system that can detect early occurrences of arrhythmias from an individual's electrocardiogram (ECG) signal. We first modelled the common causes of arrhythmias in the signal domain as a degradation of normal ECG beats to abnormal beats. Using the degradation models, we performed abnormal beat synthesis which created potential abnormal beats from the average normal beat of the individual. Finally, a Convolutional Neural Network (CNN) was trained using real normal and synthesized abnormal beats. As a personalized classifier, the trained CNN can monitor ECG beats in real time for arrhythmia detection. Over 34 patients' ECG records with a total of 63,341 ECG beats from the MIT-BIH arrhythmia benchmark database, we have shown that the probability of detecting one or more abnormal ECG beats among the first three occurrences is higher than 99.4% with a very low false-alarm rate. 1 2017 The Author(s).Scopu