Analysis of noise-induced transitions from regular to chaotic oscillations in the Chen system

The stochastically perturbed Chen system is studied within the parameter region which permits both regular and chaotic oscillations. As noise intensity increases and passes some threshold value, noise-induced hopping between close portions of the stochastic cycle can be observed. Through these transitions, the stochastic cycle is deformed to be a stochastic attractor that looks like chaotic. In this paper for investigation of these transitions, a constructive method based on the stochastic sensitivity function technique with confidence ellipses is suggested and discussed in detail. Analyzing a mutual arrangement of these ellipses, we estimate the threshold noise intensity corresponding to chaotization of the stochastic attractor. Capabilities of this geometric method for detailed analysis of the noise-induced hopping which generates chaos are demonstrated on the stochastic Chen system. © 2012 American Institute of Physics

Modeling effects of nonbreeders on population growth estimates

Acknowledgements We thank the Beissinger lab and reviewers for helpful comments on manuscript drafts. This research was funded by a Marie Curie International Outgoing Fellowship within the 7th European Community Framework Programme (project NON- BREEDERS). The contents of this paper reflect the views of the researchers, not the views of the European Commission. Data Accessibility R-code available from the Dryad Digital Repository: http://dx.doi.org/10.5061/dryad.t56cn (Lee, Reid & Beissinger, 2016).Peer reviewedPostprin

Optimizing periodicity and polymodality in noise-induced genetic oscillators

Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities in the form of period skippings, which lead to polymodal distributions of cycle lengths. A recently proposed mechanism that accounts for this quantized behavior is the stabilization of a Hopf-unstable state by molecular noise. Here we investigate the effect of varying noise in a model system, namely an excitable activator-repressor genetic circuit, that displays this noise-induced stabilization effect. Our results show that an optimal noise level enhances the regularity (coherence) of the cycles, in a form of coherence resonance. Similar noise levels also optimize the multimodal nature of the cycle lengths. Together, these results illustrate how molecular noise within a minimal gene regulatory motif confers robust generation of polymodal patterns of periodicity.Comment: 9 pages, 6 figure