Automatic Classification of Human Epithelial Type 2 Cell Indirect Immunofluorescence Images using Cell Pyramid Matching

This paper describes a novel system for automatic classification of images obtained from Anti-Nuclear Antibody (ANA) pathology tests on Human Epithelial type 2 (HEp-2) cells using the Indirect Immunofluorescence (IIF) protocol. The IIF protocol on HEp-2 cells has been the hallmark method to identify the presence of ANAs, due to its high sensitivity and the large range of antigens that can be detected. However, it suffers from numerous shortcomings, such as being subjective as well as time and labour intensive. Computer Aided Diagnostic (CAD) systems have been developed to address these problems, which automatically classify a HEp-2 cell image into one of its known patterns (eg. speckled, homogeneous). Most of the existing CAD systems use handpicked features to represent a HEp-2 cell image, which may only work in limited scenarios. We propose a novel automatic cell image classification method termed Cell Pyramid Matching (CPM), which is comprised of regional histograms of visual words coupled with the Multiple Kernel Learning framework. We present a study of several variations of generating histograms and show the efficacy of the system on two publicly available datasets: the ICPR HEp-2 cell classification contest dataset and the SNPHEp-2 dataset.Comment: arXiv admin note: substantial text overlap with arXiv:1304.126

Self-adaptive MOEA feature selection for classification of bankruptcy prediction data

Article ID 314728Bankruptcy prediction is a vast area of finance and accounting whose importance lies in the relevance for creditors and investors in evaluating the likelihood of getting into bankrupt. As companies become complex, they develop sophisticated schemes to hide their real situation. In turn, making an estimation of the credit risks associated with counterparts or predicting bankruptcy becomes harder. Evolutionary algorithms have shown to be an excellent tool to deal with complex problems in finances and economics where a large number of irrelevant features are involved.This paper provides a methodology for feature selection in classification of bankruptcy data sets using an evolutionary multiobjective approach that simultaneously minimise the number of features and maximise the classifier quality measure (e.g., accuracy).The proposed methodology makes use of self-adaptation by applying the feature selection algorithm while simultaneously optimising the parameters of the classifier used. The methodology was applied to four different sets of data. The obtained results showed the utility of using the self-adaptation of the classifier.This work was partially supported by the Portuguese Foundation for Science and Technology under Grant PEst-C/CTM/LA0025/2011 (Strategic Project-LA 25-2011-2012) and by the Spanish Ministerio de Ciencia e Innovacion, under the project "Gestion de movilidad efficiente y sostenible, MOVES" with Grant Reference TIN2011-28336

On Model- and Data-based Approaches to Structural Health Monitoring

Structural Heath Monitoring (SHM) is the term applied to the process of periodically monitoring the state of a structural system with the aim of diagnosing damage in the structure. Over the course of the past several decades there has been ongoing interest in approaches to the problem of SHM. This attention has been sustained by the belief that SHM will allow substantial economic and life-safety benefits to be realised across a wide range of applications. Several numerical and laboratory implementations have been successfully demonstrated. However, despite this research effort, real-world applications of SHM as originally envisaged are somewhat rare. Numerous technical barriers to the broader application of SHM methods have been identified, namely: severe restrictions on the availability of damaged-state data in real-world scenarios; difficulties associated with the numerical modelling of physical systems; and limited understanding of the physical effect of system inputs (including environmental and operational loads). This thesis focuses on the roles of law-based and data-based modelling in current applications of. First, established approaches to model-based SHM are introduced, with the aid of an exemplar ‘wingbox’ structure. The study highlights the degree of difficulty associated with applying model-updating-based methods and with producing numerical models capable of accurately predicting changes in structural response due to damage. These difficulties motivate the investigation of non-deterministic, predictive modelling of structural responses taking into account both experimental and modelling uncertainties. Secondly, a data-based approach to multiple-site damage location is introduced, which may allow the quantity of experimental data required for classifier training to be drastically reduced. A conclusion of the above research is the identification of hybrid approaches, in which a forward-mode law-based model informs a data-based damage identification scheme, as an area for future wor

Large-scale Nonlinear Variable Selection via Kernel Random Features

We propose a new method for input variable selection in nonlinear regression. The method is embedded into a kernel regression machine that can model general nonlinear functions, not being a priori limited to additive models. This is the first kernel-based variable selection method applicable to large datasets. It sidesteps the typical poor scaling properties of kernel methods by mapping the inputs into a relatively low-dimensional space of random features. The algorithm discovers the variables relevant for the regression task together with learning the prediction model through learning the appropriate nonlinear random feature maps. We demonstrate the outstanding performance of our method on a set of large-scale synthetic and real datasets.Comment: Final version for proceedings of ECML/PKDD 201