Highly efficient low-level feature extraction for video representation and retrieval.

PhDWitnessing the omnipresence of digital video media, the research community has raised the question of its meaningful use and management. Stored in immense multimedia databases, digital videos need to be retrieved and structured in an intelligent way, relying on the content and the rich semantics involved. Current Content Based Video Indexing and Retrieval systems face the problem of the semantic gap between the simplicity of the available visual features and the richness of user semantics. This work focuses on the issues of efficiency and scalability in video indexing and retrieval to facilitate a video representation model capable of semantic annotation. A highly efficient algorithm for temporal analysis and key-frame extraction is developed. It is based on the prediction information extracted directly from the compressed domain features and the robust scalable analysis in the temporal domain. Furthermore, a hierarchical quantisation of the colour features in the descriptor space is presented. Derived from the extracted set of low-level features, a video representation model that enables semantic annotation and contextual genre classification is designed. Results demonstrate the efficiency and robustness of the temporal analysis algorithm that runs in real time maintaining the high precision and recall of the detection task. Adaptive key-frame extraction and summarisation achieve a good overview of the visual content, while the colour quantisation algorithm efficiently creates hierarchical set of descriptors. Finally, the video representation model, supported by the genre classification algorithm, achieves excellent results in an automatic annotation system by linking the video clips with a limited lexicon of related keywords

Leveraging virtualization technologies for resource partitioning in mixed criticality systems

Multi- and many-core processors are becoming increasingly popular in embedded systems. Many of these processors now feature hardware virtualization capabilities, such as the ARM Cortex A15, and x86 processors with Intel VT-x or AMD-V support. Hardware virtualization offers opportunities to partition physical resources, including processor cores, memory and I/O devices amongst guest virtual machines. Mixed criticality systems and services can then co-exist on the same platform in separate virtual machines. However, traditional virtual machine systems are too expensive because of the costs of trapping into hypervisors to multiplex and manage machine physical resources on behalf of separate guests. For example, hypervisors are needed to schedule separate VMs on physical processor cores. Additionally, traditional hypervisors have memory footprints that are often too large for many embedded computing systems. This dissertation presents the design of the Quest-V separation kernel, which partitions services of different criticality levels across separate virtual machines, or sandboxes. Each sandbox encapsulates a subset of machine physical resources that it manages without requiring intervention of a hypervisor. In Quest-V, a hypervisor is not needed for normal operation, except to bootstrap the system and establish communication channels between sandboxes. This approach not only reduces the memory footprint of the most privileged protection domain, it removes it from the control path during normal system operation, thereby heightening security

ASSESSMENT OF RISK SCORES FOR THE PREDICTION AND DETECTION OF TYPE 2 DIABETES MELLITUS IN CLINICAL SETTINGS

Health and sociological indicators confirm that life expectancy is increasing, and so, the years that patients have to live with chronic diseases and co-morbidities. Type 2 Diabetes is one of the most common chronic diseases, specially linked to overweight and ages over sixty. As a metabolic disease, Type 2 Diabetes affects multiple organs by causing damage in blood vessels and nervous system at micro and macro scale. Mortality of subjects with diabetes is three times higher than the mortality for subjects with other chronic diseases. On the one hand, the management of diabetes is focused on the maintenance of the blood glucose levels under a threshold by the prescription of anti-diabetic drugs and a combination of healthy food habits and moderate physical activity. Recent studies have demonstrated the effectiveness of new strategies to delay and even prevent the onset of Type 2 Diabetes by a combination of active and healthy lifestyle on cohorts of mid to high risk subjects. On the other hand, prospective research has been driven on large groups of population to build risk scores which aim to obtain a rule for the classification of patients according to the odds for developing the disease. Currently there are more than two hundred models and risk scores for doing this, but a few have been properly evaluated in external groups and, to date, none of them has been tested on a population based study. The research study presented in this doctoral thesis strives to use externally validated risk scores for the prediction and detection of Type 2 Diabetes on a population data base in Hospital La Fe (Valencia, Spain). The study hypothesis is that the integration of existing prediction and detection risk scores on Electronic Health Records increases the early-detection of high risk cases. To evaluate this hypothesis three studies on the clinical, user and technology dimensions have been driven to evaluate the extent to which the models and the hospital is ready to exploit such models to identify high risk groups and drive efficient preventive strategies. The findings presented in this thesis suggest that Electronic Health Records are not prepared to massively feed risk models. Some of the evaluated models have shown a good classification performance, which accompanied to the well-acceptance of web-based tools and the acceptable technical performance of the information and communication technology system, suggests that after some work these models can effectively drive a new paradigm of active screening for Type 2 Diabetes.Los indicadores de salud y sociológicos confirman que la esperanza de vida está aumentando, y por lo tanto, los años que los pacientes tienen que vivir con enfermedades crónicas y comorbilidades. Diabetes tipo 2 es una de las enfermedades crónicas más comunes, especialmente relacionadas con el sobrepeso y edades superiores a los sesenta años. Como enfermedad metabólica, la diabetes tipo 2 afecta a múltiples órganos causando daño en los vasos sanguíneos y el sistema nervioso a escala micro y macro. La mortalidad de sujetos con diabetes es tres veces mayor que la mortalidad de sujetos con otras enfermedades crónicas. Por un lado, la estrategia de manejo se centra en el mantenimiento de los niveles de glucosa en sangre bajo un umbral mediante la prescripción de fármacos antidiabéticos y una combinación de hábitos alimentarios saludables y actividad física moderada. Estudios recientes han demostrado la eficacia de nuevas estrategias para retrasar e incluso prevenir la aparición de la diabetes tipo 2 mediante una combinación de estilo de vida activo y saludable en cohortes de sujetos de riesgo medio a alto. Por otro lado, la investigación prospectiva se ha dirigido a grupos de la población para construir modelos de riesgo que pretenden obtener una regla para la clasificación de las personas según las probabilidades de desarrollar la enfermedad. Actualmente hay más de doscientos modelos de riesgo para hacer esta identificación, no obstante la inmensa mayoría no han sido debidamente evaluados en grupos externos y, hasta la fecha, ninguno de ellos ha sido probado en un estudio poblacional. El estudio de investigación presentado en esta tesis doctoral pretende utilizar modelos riesgo validados externamente para la predicción y detección de la Diabetes Tipo 2 en una base de datos poblacional del Hospital La Fe de Valencia (España). La hipótesis del estudio es que la integración de los modelos de riesgo de predicción y detección existentes la práctica clínica aumenta la detección temprana de casos de alto riesgo. Para evaluar esta hipótesis, se han realizado tres estudios sobre las dimensiones clínicas, del usuario y de la tecnología para evaluar hasta qué punto los modelos y el hospital están dispuestos a explotar dichos modelos para identificar grupos de alto riesgo y conducir estrategias preventivas eficaces. Los hallazgos presentados en esta tesis sugieren que los registros de salud electrónicos no están preparados para alimentar masivamente modelos de riesgo. Algunos de los modelos evaluados han demostrado un buen desempeño de clasificación, lo que acompañó a la buena aceptación de herramientas basadas en la web y el desempeño técnico aceptable del sistema de tecnología de información y comunicación, sugiere que después de algún trabajo estos modelos pueden conducir un nuevo paradigma de la detección activa de la Diabetes Tipo 2.Els indicadors sociològics i de salut confirmen un augment en l'esperança de vida, i per tant, dels anys que les persones han de viure amb malalties cròniques i comorbiditats. la diabetis de tipus 2 és una de les malalties cròniques més comunes, especialment relacionades amb l'excés de pes i edats superiors als seixanta anys. Com a malaltia metabòlica, la diabetis de tipus 2 afecta múltiples òrgans causant dany als vasos sanguinis i el sistema nerviós a escala micro i macro. La mortalitat de subjectes amb diabetis és tres vegades superior a la mortalitat de subjectes amb altres malalties cròniques. D'una banda, l'estratègia de maneig se centra en el manteniment dels nivells de glucosa en sang sota un llindar mitjançant la prescripció de fàrmacs antidiabètics i una combinació d'hàbits alimentaris saludables i activitat física moderada. Estudis recents han demostrat l'eficàcia de noves estratègies per a retardar i fins i tot prevenir l'aparició de la diabetis de tipus 2 mitjançant una combinació d'estil de vida actiu i saludable en cohorts de subjectes de risc mitjà a alt. D'altra banda, la investigació prospectiva s'ha dirigit a grups específics de la població per construir models de risc que pretenen obtenir una regla per a la classificació de les persones segons les probabilitats de desenvolupar la malaltia. Actualment hi ha més de dos-cents models de risc per fer aquesta identificació, però la immensa majoria no han estat degudament avaluats en grups externs i, fins ara, cap d'ells ha estat provat en un estudi poblacional. L'estudi d'investigació presentat en aquesta tesi doctoral utilitza models de risc validats externament per a la predicció i detecció de diabetis de tipus 2 en una base de dades poblacional de l'Hospital La Fe de València (Espanya). La hipòtesi de l'estudi és que la integració dels models de risc de predicció i detecció existents la pràctica clínica augmenta la detecció de casos d'alt risc. Per avaluar aquesta hipòtesi, s'han realitzat tres estudis sobre les dimensions clíniques, de l'usuari i de la tecnologia per avaluar fins a quin punt els models i l'hospital estan disposats a explotar aquests models per identificar grups d'alt risc i conduir estratègies preventives. Les troballes presentades sugereixen que els registres de salut electrònics no estan preparats per alimentar massivament models de risc. Alguns dels models avaluats han demostrat una bona classificació, el que va acompanyar a la bona acceptació d'eines basades en el web i el rendiment tècnic acceptable del sistema de tecnologia d'informació i comunicacions implementat. La conclusió es que encara es necesari treball per que aquests models poden conduir un nou paradigma de la detecció activa de la diabetis de tipus 2.Martínez Millana, A. (2017). ASSESSMENT OF RISK SCORES FOR THE PREDICTION AND DETECTION OF TYPE 2 DIABETES MELLITUS IN CLINICAL SETTINGS [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/86209TESI

Design of rate-adaptive MAC and medium aware routing protocols for multi-rate, multi-hop wireless networks

This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The IEEE 802.11 standard conformant wireless communication stations have multi-rate transmission capability. To achieve greater communication efficiency, multi-rate capable stations use rateadaptation to select appropriate transmission rate according to variations in the channel quality. The thesis presents two rate-adaptation schemes, each belonging to one of the two classes of rateadaptation schemes i.e.(1) the frame-transmission statistics based schemes, and (2) Signal-to-Noise Ratio (SNR) based, closed loop schemes. The SNR-based rate-adaptation scheme, proposed in this thesis uses a novel mechanism of delivering a receiver’s feedback to a transmitter; without requiring any modification in the standard frames as suggested by existing research. The frame-transmissionstatistics based rate adaptation solution uses an on-demand incremental strategy for selecting a rate-selection threshold. This solution is based on a cross-layer communication framework, where the rate-adaptation module uses information to/from the Application layer along with relevant information from the Medium Access Control (MAC) sub-layer. The proposed solutions are highly responsive when compared with existing rate-adaptation schemes; responsiveness is one of the key factors in the design of such protocols. The novel feedback mechanism makes it possible to achieve frame-loss differentiation with just three frames, avoiding the use of Request To Send/ Clear To Send (RTS/CTS) frames and further delays in this process. Performance tests have affirmed that the proposed rate-adaptation schemes are energy efficient; with efficiency up to 19% in specific test scenarios. In terms of throughput and frame loss-differentiation mechanisms, the proposed schemes have shown significantly better performance.Routing protocols for Mobile Ad-Hoc Networks (MANETs) use broadcast frames during the route discovery process. The 802.11 mandates the use of different transmission rates for broadcast and unicast (data-) frames. In many cases it causes creation of communication gray zones, where stations which are marked as ‘reachable neighbours’ using the broadcast frames (using lower transmission rate) are not accessible during normal, unicast communication (mainly at a higher rate). Similarly, higher device density, interference and mobility cause variable medium access delays. The IEEE 802.11e introduces four different MAC level queues for four access categories, maintaining service priority within the queues; which implies that frames from a higher priority queue are serviced more frequently than those belonging to lower priority queues. Such an enhancement at the MAC sub-layer introduces uneven queuing delays. Conventional routing protocols are unaware of such MAC specific constraints and as a result these factors are not considered which result in severe performance deterioration. To meet such challenges, the thesis presents a medium aware distance vector (MADV) routing protocol for MANETs. MADV uses MAC and physical layer (PHY) specific information in the route metric and maintains a separate route per-AC-per-destination in its routing tables. The MADV-metric can be incorporated into various routing rotocols and its applicability is determined by the possibility of provision of MAC dependent arameters that are used to determine the hop-by-hop MADV-metric values. Simulation tests and omparison with existing MANET protocols demonstrate the effectiveness of incorporating the medium dependent parameters and show that MADV is significantly better in terms of end-to-end delay and throughput

Technical Design Report for the PANDA Micro Vertex Detector

This document illustrates the technical layout and the expected performance of the Micro Vertex Detector (MVD) of the PANDA experiment. The MVD will detect charged particles as close as possible to the interaction zone. Design criteria and the optimisation process as well as the technical solutions chosen are discussed and the results of this process are subjected to extensive Monte Carlo physics studies. The route towards realisation of the detector is outlined