21,232 research outputs found

    A general framework for positioning, evaluating and selecting the new generation of development tools.

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    This paper focuses on the evaluation and positioning of a new generation of development tools containing subtools (report generators, browsers, debuggers, GUI-builders, ...) and programming languages that are designed to work together and have a common graphical user interface and are therefore called environments. Several trends in IT have led to a pluriform range of developments tools that can be classified in numerous categories. Examples are: object-oriented tools, GUI-tools, upper- and lower CASE-tools, client/server tools and 4GL environments. This classification does not sufficiently cover the tools subject in this paper for the simple reason that only one criterion is used to distinguish them. Modern visual development environments often fit in several categories because to a certain extent, several criteria can be applied to evaluate them. In this study, we will offer a broad classification scheme with which tools can be positioned and which can be refined through further research.

    Towards data grids for microarray expression profiles

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    The UK DTI funded Biomedical Research Informatics Delivered by Grid Enabled Services (BRIDGES) project developed a Grid infrastructure through which research into the genetic causes of hypertension could be supported by scientists within the large Wellcome Trust funded Cardiovascular Functional Genomics project. The BRIDGES project had a focus on developing a compute Grid and a data Grid infrastructure with security at its heart. Building on the work within BRIDGES, the BBSRC funded Grid enabled Microarray Expression Profile Search (GEMEPS) project plans to provide an enhanced data Grid infrastructure to support richer queries needed for the discovery and analysis of microarray data sets, also based upon a fine-grained security infrastructure. This paper outlines the experiences gained within BRIDGES and outlines the status of the GEMEPS project, the open challenges that remain and plans for the future

    A Data Transformation System for Biological Data Sources

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    Scientific data of importance to biologists in the Human Genome Project resides not only in conventional databases, but in structured files maintained in a number of different formats (e.g. ASN.1 and ACE) as well a.s sequence analysis packages (e.g. BLAST and FASTA). These formats and packages contain a number of data types not found in conventional databases, such as lists and variants, and may be deeply nested. We present in this paper techniques for querying and transforming such data, and illustrate their use in a prototype system developed in conjunction with the Human Genome Center for Chromosome 22. We also describe optimizations performed by the system, a crucial issue for bulk data

    Managing contextual information in semantically-driven temporal information systems

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    Context-aware (CA) systems have demonstrated the provision of a robust solution for personalized information delivery in the current content-rich and dynamic information age we live in. They allow software agents to autonomously interact with users by modeling the user’s environment (e.g. profile, location, relevant public information etc.) as dynamically-evolving and interoperable contexts. There is a flurry of research activities in a wide spectrum at context-aware research areas such as managing the user’s profile, context acquisition from external environments, context storage, context representation and interpretation, context service delivery and matching of context attributes to users‘ queries etc. We propose SDCAS, a Semantic-Driven Context Aware System that facilitates public services recommendation to users at temporal location. This paper focuses on information management and service recommendation using semantic technologies, taking into account the challenges of relationship complexity in temporal and contextual information

    Towards a service-oriented e-infrastructure for multidisciplinary environmental research

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    Research e-infrastructures are considered to have generic and thematic parts. The generic part provids high-speed networks, grid (large-scale distributed computing) and database systems (digital repositories and data transfer systems) applicable to all research commnities irrespective of discipline. Thematic parts are specific deployments of e-infrastructures to support diverse virtual research communities. The needs of a virtual community of multidisciplinary envronmental researchers are yet to be investigated. We envisage and argue for an e-infrastructure that will enable environmental researchers to develop environmental models and software entirely out of existing components through loose coupling of diverse digital resources based on the service-oriented achitecture. We discuss four specific aspects for consideration for a future e-infrastructure: 1) provision of digital resources (data, models & tools) as web services, 2) dealing with stateless and non-transactional nature of web services using workflow management systems, 3) enabling web servce discovery, composition and orchestration through semantic registries, and 4) creating synergy with existing grid infrastructures
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