348 research outputs found
Individualised Modelling for Preoperative Planning of Total Knee Replacement Surgery
Total knee replacement (TKR) surgery is routinely prescribed for patients with severe knee osteoarthritis to alleviate the pain and restore the kinematics. Although this procedure was proven to be successful in reducing the joint pain, the number of failures and the low patients’ satisfaction suggest that while the number of reoperations is small, the surgery frequently fail to restore the function in full. The main cause are surgical techniques which inadequately address the problem of balancing the knee soft tissues.
The preoperative planning technique allows to manufacture subject-specific cutting guides that improves the placement of the prosthesis, however the knee soft tissue is ignored.
The objective of this dissertation was to create an optimized preplanning procedure to compute the soft tissue balance along with the placement of the prosthesis to ensure mechanical stability.
The dissertation comprises the development of CT based static and quasi-static knee models able to estimate the postoperative length of the collateral lateral ligaments using a dataset of seven TKR patients; In addition, a subject-specific dynamic musculoskeletal model of the lower limb was created using in vivo knee contact forces to perform the same analysis during walking. The models were evaluated by their ability to predict the postoperative elongation using a threshold based on the 10 % of the preoperative length, through which the model detected whether an elongation was acceptable.
The results showed that the subject-specific static model is the best solution to be included in the optimized, subject-specific, preoperative planning framework; full order musculoskeletal model allowed to estimate the postoperative length of the ligaments during walking, and at least in principle while performing any other activity.
Unlike the current methodology used in clinic this optimized preoperative planning framework might help the surgeon to understand how the position of the TKR affects the knee soft tissue
Computational Tools and Experimental Methods for the Development of Passive Prosthetic Feet
Modern prosthetic foot designs are incredibly diverse in comparison to what was o↵ered to amputees at the turn of the millennium. Powered ankles can supply natural levels of joint torque, whilst passive feet continue to optimise for kinematic goals. However, most passive feet still do not solve the issue of unhealthy loads, and an argument can be made that optimisation methods have neglected the less active and elderly amputee. This thesis creates a framework for a novel approach to prosthetic foot optimisation by focusing on the transitionary motor tasks of gait initiation and termination.An advanced FEA model has been created in ANSYS® using boundary con-ditions derived from an ISO testing standard that replicates stance phase loading. This model can output standard results found in the literature and goes beyond by parameterising the roll-over shape within the software using custom APDL code. Extensive contact exploration and an experimental study have ensured the robustness of the model. Subject force and kinematic data can be used for specific boundary conditions, which would allow for easy adaptation to the transitionary motor tasks.This FEA model has been used in the development of prosthetic experiment tool, which can exchange helical springs to assess e↵ects of small changes in sti↵-ness on gait metrics. A rigorous design methodology was employed for all compo-nents, including parametric design studies, response surface optimisation, and ISO level calculations. The design has been manufactured into a working prototype and is ready for clinical trials to determine its efficacy.The conclusion of this framework is in the development of an experimental method to collect subject data for use in the models. A pilot study uncovered reliable protocols, which were then verified with ANOVA statistics. Proportional ratios were defined as additions to metric peak analyses already found in the liter-ature. These tools are ready for deployment in full clinical trials with amputees, so that a new prosthetic optimisation pathway can be discovered for the benefit of less active or elderly amputees
A multibody approach to the contact dynamics: a knee joint application
In this thesis, a general approach for dynamic analysis of multibody systems with contact is presented, being a special attention given to the articular contact at the human knee joint. Two methodologies, in two- and three-dimensions, for knee contact modeling are proposed under the framework of multibody systems using generalized Cartesian coordinates. The development of the planar multibody knee model encompasses four steps: (i) geometrical representation of contacting profiles by means of curve fitting techniques based on spline interpolation functions; (ii) location of contact points and evaluation of the contact indentation; (iii) calculation of the contact forces by using an appropriate constitutive law; (iv) description of the ligament behavior by a quadratic stress-strain relation. The motion of the tibia relative to the femur is modeled combining the action of the knee ligaments with the potential contacts between the bones. The contact forces, together with the forces produced by the ligaments, are introduced into the Newton-Euler equations of motion as external generalized forces. Within the three-dimensional methodology, the contact surfaces are described by means of point-clouds extracted from parametric representations. The spatial formulation presents a pre-processing unit. This preprocessor allows for a significantly reduction of the amount of memory required for data storage and an improvement of the computational efficiency of the contact detection process. Computational simulations were performed with the aim of validating both proposed approaches, two-dimensional and three-dimensional. The behavior of the planar knee model resultant of the application of different contact force laws was studied. Moreover, the influence of the geometric and material properties on the dynamic response of the knee joint model was investigated. In a broad sense, the proposed methodologies demonstrated to be suitable for the analysis of the dynamic behavior of multibody models with contact, especially those biological systems such as the knee joint that involve complex geometries, a large range of motion and high dynamic loads.Nesta tese é proposta uma abordagem genérica para a análise dinâmica de sistemas de corpos múltiplos com contacto, dando um especial enfoque ao contacto articular no joelho humano. No âmbito da dinâmica de sistemas de corpos múltiplos são apresentadas duas metodologias, bidimensional e tridimensional, para a modelação do contacto no joelho usando coordenadas cartesianas generalizadas. O desenvolvimento do modelo bidimensional do joelho engloba quatro etapas: (i) representação geométrica dos perfis de contacto por meio de técnicas de ajuste de curva com base em funções de interpolação por splines, (ii) localização dos pontos de contacto e avaliação da indentação de contacto, (iii) cálculo das forças de contacto usando uma lei constitutiva apropriada, (iv) descrição do comportamento dos ligamentos através de uma relação quadrática de tensão-deformação. O movimento da tíbia em relação ao fémur é modelado como uma acção combinada entre os ligamentos do joelho e os potenciais contactos entre os ossos. As forças de contacto, juntamente com as forças produzidas pelos ligamentos, são introduzidas nas equações de movimento de Newton-Euler como forças externas generalizadas. Na metodologia tridimensional, as superfícies de contacto são descritas por meio de nuvens de pontos extraídas de representações paramétricas. No âmbito da formulação tridimensional é apresentada uma unidade de pré-processamento. Este pré-processador permite uma redução significativa da quantidade de memória necessária para o armazenamento de dados e, desta forma, melhora a eficiência computacional do algoritmo de deteção de contacto. Com o objetivo de validar as metodologias propostas, realizaram-se várias simulações computacionais. Os comportamentos do modelo bidimensional do joelho resultantes da aplicação de diferentes leis de força de contacto foram estudados. A influência das propriedades geométricas e de material na resposta dinâmica do modelo bidimensional do joelho foi investigada. De uma forma geral, as metodologias propostas demonstraram ser adequadas para a análise do comportamento dinâmico de modelos de corpos múltiplos com contacto, especialmente sistema biológicos, como o joelho humano, que envolvem geometrias complexas, uma grande amplitude de movimentos e elevadas cargas dinâmicas
Rehabilitation Engineering
Population ageing has major consequences and implications in all areas of our daily life as well as other important aspects, such as economic growth, savings, investment and consumption, labour markets, pensions, property and care from one generation to another. Additionally, health and related care, family composition and life-style, housing and migration are also affected. Given the rapid increase in the aging of the population and the further increase that is expected in the coming years, an important problem that has to be faced is the corresponding increase in chronic illness, disabilities, and loss of functional independence endemic to the elderly (WHO 2008). For this reason, novel methods of rehabilitation and care management are urgently needed. This book covers many rehabilitation support systems and robots developed for upper limbs, lower limbs as well as visually impaired condition. Other than upper limbs, the lower limb research works are also discussed like motorized foot rest for electric powered wheelchair and standing assistance device
Review of Modelling Techniques for In Vivo
Background. Knowledge of the musculoskeletal loading conditions during strength training is essential for performance monitoring, injury prevention, rehabilitation, and training design. However, measuring muscle forces during exercise performance as a primary determinant of training efficacy and safety has remained challenging. Methods. In this paper we review existing computational techniques to determine muscle forces in the lower limbs during strength exercises in vivo and discuss their potential for uptake into sports training and rehabilitation. Results. Muscle forces during exercise performance have almost exclusively been analysed using so-called forward dynamics simulations, inverse dynamics techniques, or alternative methods. Musculoskeletal models based on forward dynamics analyses have led to considerable new insights into muscular coordination, strength, and power during dynamic ballistic movement activities, resulting in, for example, improved techniques for optimal performance of the squat jump, while quasi-static inverse dynamics optimisation and EMG-driven modelling have helped to provide an understanding of low-speed exercises. Conclusion. The present review introduces the different computational techniques and outlines their advantages and disadvantages for the informed usage by nonexperts. With sufficient validation and widespread application, muscle force calculations during strength exercises in vivo are expected to provide biomechanically based evidence for clinicians and therapists to evaluate and improve training guidelines
Design of an Elastic Actuation System for a Gait-Assistive Active Orthosis for Incomplete Spinal Cord Injured Subjects
A spinal cord injury severely reduces the quality of life of affected people. Following the injury,
limitations of the ability to move may occur due to the disruption of the motor and sensory functions
of the nervous system depending on the severity of the lesion. An active stance-control
knee-ankle-foot orthosis was developed and tested in earlier works to aid incomplete SCI subjects
by increasing their mobility and independence. This thesis aims at the incorporation of
elastic actuation into the active orthosis to utilise advantages of the compliant system regarding
efficiency and human-robot interaction as well as the reproduction of the phyisological compliance
of the human joints. Therefore, a model-based procedure is adapted to the design of
an elastic actuation system for a gait-assisitve active orthosis. A determination of the optimal
structure and parameters is undertaken via optimisation of models representing compliant actuators
with increasing level of detail. The minimisation of the energy calculated from the positive
amount of power or from the absolute power of the actuator generating one human-like gait cycle
yields an optimal series stiffness, which is similar to the physiological stiffness of the human
knee during the stance phase. Including efficiency factors for components, especially the consideration
of the electric model of an electric motor yields additional information. A human-like
gait cycle contains high torque and low velocities in the stance phase and lower torque combined
with high velocities during the swing. Hence, the efficiency of an electric motor with a gear unit
is only high in one of the phases. This yields a conceptual design of a series elastic actuator with
locking of the actuator position during the stance phase. The locked position combined with the
series compliance allows a reproduction of the characteristics of the human gait cycle during
the stance phase. Unlocking the actuator position for the swing phase enables the selection of
an optimal gear ratio to maximise the recuperable energy. To evaluate the developed concept,
a laboratory specimen based on an electric motor, a harmonic drive gearbox, a torsional series
spring and an electromagnetic brake is designed and appropriate components are selected. A
control strategy, based on impedance control, is investigated and extended with a finite state
machine to activate the locking mechanism. The control scheme and the laboratory specimen
are implemented at a test bench, modelling the foot and shank as a pendulum articulated at the
knee. An identification of parameters yields high and nonlinear friction as a problem of the system,
which reduces the energy efficiency of the system and requires appropriate compensation.
A comparison between direct and elastic actuation shows similar results for both systems at the
test bench, showing that the increased complexity due to the second degree of freedom and
the elastic behaviour of the actuator is treated properly. The final proof of concept requires the
implementation at the active orthosis to emulate uncertainties and variations occurring during
the human gait
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A Generalized Method for Predictive Simulation-Based Lower Limb Prosthesis Design
Lower limb prostheses are designed to replace the functions and form of the missing biological anatomy. These functions are hypothesized to improve user outcome measures which are negatively affected by receiving an amputation – such as metabolic cost of transport, preferred walking speed, and perceived discomfort during walking. However, the effect of these design functions on the targeted outcome measures is highly variable, suggesting that these relationships are not fully understood. Biomechanics simulation and modeling tools are increasingly capable of analyzing the effects of a design on the resulting user gait. In this work, prothesis-aided gait is optimized in simulation to reduce both muscle effort and peak loads on the residual limb using a generalized prosthesis model. Compared to a traditional revolute powered ankle joint model, a two degree-of freedom generalized model reduced muscle activations by 50% and peak loads by 15%. Simulated prosthesis behaviors corresponding to the optimal gait patterns were translated into a two degree-of-freedom ankle-foot prosthesis design with powered bidirectional linear translation and plantarflexion. The prototype is capable of delivering up to 171 N-m of plantarflexion torque and 499 N of translation force, with 15° dorsi-/35° plantarflexion and 10 cm translation range of motion. The mass and height of the ankle-foot are 2.29 kg and 19.5 cm, respectively. The mass of the entire system including the wearable offboard system is 8.58 kg. This platform is designed to emulate the behavior of the simulated prosthesis, as well as be configurable to emulate alternate behaviors obtained from simulations with different optimization objectives. The prototype is controlled to replicate simulated walking patterns using a high level finite state controller, mid-level stiffness controller, and low level load controller. Closed loop load control has bandwidth of 15 Hz in translation and 7.2 Hz in flexion. Load tracking during walking with a single able-bodied human subject ranges from 93 to 159 N in translation and 4.6 to 21.3 N-m in flexion. The contribution of this work is to provide a framework for predictive simulation-based prosthesis design, evidence of its practical implementation, and the experimental tools to validate future predictive simulation studies
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A Lower Limb Prosthesis with Active Alignment for Reduced Limb Loading
Over the past decade, the growing field of robotics has created new possibilities in lower limb prostheses. The focus of these new prostheses has been replicating the dynamics of the lost limb in order to restore gait of individuals with lower limb amputations to healthy norms. This places demanding loads on the residual limb. Compensation by the rest of body is high, causes overloading of intact joints and can lead to deterioration of mobility and overall health. Abnormalities remain present in the person’s gait, stemming from the loading of soft tissue and the altered anatomy of the affected limb. In this dissertation, an experimental prosthesis is developed with systematic, simulation based techniques. Kinematics and kinetics of the prosthesis design are altered in order to actively realign the limb in relation to the center of pressure during stance, allowing positive power to be generated by the prosthesis while actively reducing the magnitude of the sagittal moment transferred to the residual limb. Initial findings show that during walking with the experimental device compared to a daily use prosthesis, peak pressures on the residual limb are lowered by over 10% while maintaining walking speed
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