883 research outputs found

    Ideal Reasoners don’t Believe in Zombies

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    The negative zombie argument concludes that physicalism is false from the premises that p ∧q is ideally negatively conceivable and that what is ideally negatively conceivable is possible, where p is the conjunction of the fundamental physical truths and laws and q is a phenomenal truth (Chalmers 2002; 2010). A sentence φ is ideally negatively conceivable iff φ is not ruled out a priori on ideal rational reflection. In this paper, I argue that the negative zombie argument is neither a priori nor conclusive. First, I argue that the premises of the argument are true only if there exists an adequate finite ideal reasoner R that believes ◊(p ∧ ÂŹq) on the basis of not believing p→q on a priori basis. Roughly, a finite reasoner is a reasoner with cognitive limitations (e.g. finite memory). I argue that R is finite only if R reasons nonmonotonically and only approach ideal reflection at the limit of a reasoning sequence. This would render the argument nonconclusive. Finally, I argue that, for some q, R does not believe ◊(p ∧ ÂŹq) on the basis of not believing p→q on a priori basis (e.g. for q =‘something is conscious’). This would render the choice of an adequate q dependent on empirical information (and the argument a posteriori). I conclude that the negative zombie argument (and, maybe, all zombie arguments) is neither a priori nor conclusive

    Some resonances between Eastern thought and Integral Biomathics in the framework of the WLIMES formalism for modelling living systems

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    Forty-two years ago, Capra published “The Tao of Physics” (Capra, 1975). In this book (page 17) he writes: “The exploration of the atomic and subatomic world in the twentieth century has 
. necessitated a radical revision of many of our basic concepts” and that, unlike ‘classical’ physics, the sub-atomic and quantum “modern physics” shows resonances with Eastern thoughts and “leads us to a view of the world which is very similar to the views held by mystics of all ages and traditions.“ This article stresses an analogous situation in biology with respect to a new theoretical approach for studying living systems, Integral Biomathics (IB), which also exhibits some resonances with Eastern thought. Stepping on earlier research in cybernetics1 and theoretical biology,2 IB has been developed since 2011 by over 100 scientists from a number of disciplines who have been exploring a substantial set of theoretical frameworks. From that effort, the need for a robust core model utilizing advanced mathematics and computation adequate for understanding the behavior of organisms as dynamic wholes was identified. At this end, the authors of this article have proposed WLIMES (Ehresmann and Simeonov, 2012), a formal theory for modeling living systems integrating both the Memory Evolutive Systems (Ehresmann and Vanbremeersch, 2007) and the Wandering Logic Intelligence (Simeonov, 2002b). Its principles will be recalled here with respect to their resonances to Eastern thought

    Transitivity vs. Intransitivity in decision making process. (An example in quantum game theory)

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    We compare two different ways of quantization a simple sequential game Cat's Dilemma in the context of the debate on intransitive and transitive preferences. This kind of analysis can have essential meaning for the research on the artificial intelligence (some possibilities are discussed). Nature has both properties transitive and intransitive and maybe quantum models can be more able to capture this dualism than classical one. We also present electoral interpretation of the game.Comment: 18 pages, 3 figure

    Endogenous preferences in games with type indeterminate players

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    The Type Indeterminacy model is a theoretical framework that uses some elements of quantum formalism to model the constructive preference perspective suggested by Kahneman and Tversky. In this paper we extend the TI-model from simple to strategic decision-making and show that TI-games open a new field of strategic interaction. We first establish an equivalence result between static games of incomplete information and static TI-games. We next develop a new solution concept for non-commuting dynamic TI-games. The updating rule captures the novelty brought about by Type Indeterminacy namely that in addition to affecting information and payoffs, the action of a player impacts on the profile of types. We provide an example showing that TI-game predictions cannot be obtained as Bayes Nash equilibrium of the corresponding classical game.type indeterminacy ; games ; endogeneous preferences

    Classification of Approaches to Technological Resurrection

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    Abstract. Death seems to be a permanent event, but there is no actual proof of its irreversibility. Here we list all known ways to resurrect the dead that do not contradict our current scientific understanding of the world. While no method is currently possible, many of those listed here may become feasible with future technological development, and it may even be possible to act now to increase their probability. The most well-known such approach to technological resurrection is cryonics. Another method is indirect mind uploading, or digital immortality, namely the preservation of data about a person to allow for future reconstruction by powerful AI. More speculative ways to immortality include combinations of future superintelligence on a galactic scale, which could use simulation to resurrect all possible people, and new physical laws, which may include time-travel or obtaining information from the past. Acausal trade with parallel worlds could help combine random resurrection and reconstruction based on known data without loss of share of worlds where I exist (known as existence measure). Quantum immortality could help to increase the probability of success for cryonics and digital immortality. There many possible approaches to technological resurrection and thus if large-scale future technological development occurs, some form of resurrection is inevitable

    The tip of the iceberg: placebo, experimenter expectation and interference phenomena in subconscious information flow

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    A multi-disciplinary dialogue on the experimental evidence for nonlocal bio-communication, its emergent characteristics, impact on mainstream sciences and future research directions.

    In silico Drug Repurposing for COVID-19: Targeting SARS-CoV-2 Proteins through Docking and Quantum Mechanical Scoring

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    In December 2019, an infectious disease caused by the coronavirus SARS-CoV-2 appeared in Wuhan, China. This disease (COVID-19) spread rapidly worldwide, and on March 2020 was declared a pandemic by the World Health Organization (WHO). Today, almost 1,5 million people have been infected, with more than 85,000 casualties. Today, no vaccine nor antiviral drug is available. While the development of a vaccine might take at least a year, and for a novel drug, even longer; finding a new use to an old drug (drug repurposing) could be the most effective strategy. We present a docking-based screening using a quantum mechanical scoring of a library built from approved drugs and compounds undergoing clinical trials, against three SARS-CoV-2 target proteins: the spike or S-protein, and two proteases, the main protease and the papain-like protease. The S-protein binds directly to the Angiotensin Converting Enzyme 2 receptor of the human host cell surface, while the two proteases process viral polyproteins. Following the anaylysis of our structure-based compound screening, we propose several structurally diverse compounds (either FDA-approved or in clinical trials) that could display antiviral activity against SARS-CoV-2. Clearly, these compounds should be further evaluated in experimental assays and clinical trials to confirm their actual activity against the disease. We hope that these findings may contribute to the rational drug design against COVID-19.Fil: Cavasotto, Claudio Norberto. Universidad Austral. Facultad de Ciencias Biomédicas; Argentina. Universidad Austral. Facultad de Ciencias Biomédicas. Instituto de Investigaciones en Medicina Traslacional. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones en Medicina Traslacional; ArgentinaFil: Di Filippo, Juan Ignacio. Universidad Austral. Facultad de Ciencias Biomédicas. Instituto de Investigaciones en Medicina Traslacional. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Instituto de Investigaciones en Medicina Traslacional; Argentin
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