Design and analysis of short word length DSP systems for mobile communication

Recently, many general purpose DSP applications such as Least Mean Squares-Like single-bit adaptive filter algorithms have been developed using the Short Word Length (SWL) technique and have been shown to achieve similar performance as multi-bit systems. A key function in SWL systems is sigma delta modulation (ΣΔM) that operates at an over sampling ratio (OSR), in contrast to the Nyquist rate sampling typically used in conventional multi-bit systems. To date, the analysis of SWL (or single-bit) DSP systems has tended to be performed using high-level tools such as MATLAB, with little work reported relating to their hardware implementation, particularly in Field Programmable Gate Arrays (FPGAs). This thesis explores the hardware implementation of single-bit systems in FPGA using the design and implementation in VHDL of a single-bit ternary FIR-like filter as an illustrative example. The impact of varying OSR and bit-width of the SWL filter has been determined, and a comparison undertaken between the area-performance-power characteristics of the SWL FIR filter compared to its equivalent multi-bit filter. In these experiments, it was found that single-bit FIR-like filter consistently outperforms the multi-bit technique in terms of its area, performance and power except at the highest filter orders analysed in this work. At higher orders, the ΣΔ approach retains its power and performance advantages but exhibits slightly higher chip area. In the second stage of thesis, three encoding techniques called canonical signed digit (CSD), 2’s complement, and Redundant Binary Signed Digit (RBSD) were designed and investigated on the basis of area-performance in FPGA at varying OSR. Simulation results show that CSD encoding technique does not offer any significant improvement as compared to 2’s complement as in multi-bit domain. Whereas, RBSD occupies double the chip area than other two techniques and has poor performance. The stability of the single-bit FIR-like filter mainly depends upon IIR remodulator due to its recursive nature. Thus, we have investigated the stability IIR remodulator and propose a new model using linear analysis and root locus approach that takes into account the widely accepted second order sigma-delta modulator state variable upper bounds. Using proposed model we have found new feedback parameters limits that is a key parameter in single-bit IIR remodulator stability analysis. Further, an analysis of single-bit adaptive channel equalization in MATLAB has been performed, which is intended to support the design and development of efficient algorithm for single-bit channel equalization. A new mathematical model has been derived with all inputs, coefficients and outputs in single-bit domain. The model was simulated using narrowband signals in MATLAB and investigated on the basis of symbol error rate (SER), signal-to-noise ratio (SNR) and minimum mean squared error (MMSE). The results indicate that single-bit adaptive channel equalization is achievable with narrowband signals but that the harsh quantization noise has great impact in the convergence

Exploring the Multifaceted Roles of Glycosaminoglycans (GAGs) - New Advances and Further Challenges

Glycosaminoglycans are linear, anionic polysaccharides (GAGs) consisting of repeating disaccharides. GAGs are ubiquitously localized throughout the extracellular matrix (ECM) and to the cell membranes of cells in all tissues. They are either conjugated to protein cores in the form of proteoglycans, e.g., chondroitin/dermatan sulfate (CS/DS), heparin/heparan sulfate (Hep/HS) and keratan sulfate (KS), as well as non-sulfated hyaluronan (HA). By modulating biological signaling GAGs participate in the regulation of homeostasis and also participate in disease progression. The book, entitled “Exploring the multifaceted roles of glycosaminoglycans (GAGs)—new advances and further challenges”, features original research and review articles. These articles cover several GAG-related timely topics in structural biology and imaging; morphogenesis, cancer, and other disease therapy and drug developments; tissue engineering; and metabolic engineering. This book also includes an article illustrating how metabolic engineering can be used to create the novel chondroitin-like polysaccharide.A prerequisite for communicating in any discipline and across disciplines is familiarity with the appropriate terminology. Several nomenclature rules exist in the field of biochemistry. The historical description of GAGs follows IUPAC and IUB nomenclature. New structural depictions such as the structural nomenclature for glycan and their translation into machine-readable formats have opened the route for cross-references with popular bioinformatics resources and further connections with other exciting “omics” fields

XXIV congreso anual de la sociedad española de ingeniería biomédica (CASEIB2016)

En la presente edición, más de 150 trabajos de alto nivel científico van a ser presentados en 18 sesiones paralelas y 3 sesiones de póster, que se centrarán en áreas relevantes de la Ingeniería Biomédica. Entre las sesiones paralelas se pueden destacar la sesión plenaria Premio José María Ferrero Corral y la sesión de Competición de alumnos de Grado en Ingeniería Biomédica, con la participación de 16 alumnos de los Grados en Ingeniería Biomédica a nivel nacional. El programa científico se complementa con dos ponencias invitadas de científicos reconocidos internacionalmente, dos mesas redondas con una importante participación de sociedades científicas médicas y de profesionales de la industria de tecnología médica, y dos actos sociales que permitirán a los participantes acercarse a la historia y cultura valenciana. Por primera vez, en colaboración con FENIN, seJane Campos, R. (2017). XXIV congreso anual de la sociedad española de ingeniería biomédica (CASEIB2016). Editorial Universitat Politècnica de València. http://hdl.handle.net/10251/79277EDITORIA