31,793 research outputs found
Sponsorship image and value creation in E-sports
.E-sports games can drive the sports industry forward and sponsorship is the best way to engage consumers of this new sport. The purpose of this study is to examine the effect of sponsorship image and consumer participation in co-creation consumption activities on fans’ sponsorship response (represented by the variables interest, purchase intention and word of mouth) in e-sports. Four antecedent variables build sponsorship image (i.e., ubiquity of sport, sincerity of sponsor, attitude to sponsor and team identification). A quantitative approach is used for the purposes of this study. Some 445 questionnaires were filled in by fans who watch e-sports in Spain; these are analyzed using partial least squares structural equation modeling (PLS-SEM). The outcomes show that sponsor antecedents are crucial factors if a sponsor wants to change their sponsorship image and influence sponsorship response, and that it is also possible to use participation to improve responsesS
The applied psychology of addictive orientations : studies in a 12-step treatment context.
The clinical data for the studies was collected at The PROMIS Recovery Centre, a Minnesota Model treatmentc entre for addictions,w hich encouragesth e membership and use of the 12 step Anonymous Fellowships, and is abstinence based. The area of addiction is contextualised in a review chapter which focuses on research relating to the phenomenon of cross addiction. A study examining the concept of "addictive orientations" in male and female addicts is described, which develops a study conductedb y StephensonM, aggi, Lefever, & Morojele (1995). This presents study found a four factor solution which appeared to be subdivisions of the previously found Hedonism and Nurturance factors. Self orientated nurturance (both food dimensions, shopping and caffeine), Other orientated nurturance (both compulsive helping dimensions and work), Sensation seeking hedonism (Drugs, prescription drugs, nicotine and marginally alcohol), and Power related hedonism (Both relationship dimensions, sex and gambling. This concept of "addictive orientations" is further explored in a non-clinical population, where again a four factor solution was found, very similar to that in the clinical population. This was thought to indicate that in terms of addictive orientation a pattern already exists in this non-clinical population and that consideration should be given to why this is the case. These orientations are examined in terms of gender differences. It is suggested that the differences between genders reflect power-related role relationships between the sexes. In order to further elaborate the significance and meaning behind these orientations, the next two chapters look at the contribution of personality variables and how addictive orientations relate to psychiatric symptomatology. Personality variables were differentially, and to a considerable extent predictably involved with the four factors for both males and females.Conscientiousness as positively associated with "Other orientated Nurturance" and negatively associated with "Sensation seeking hedonism" (particularly for men). Neuroticism had a particularly strong association with the "Self orientated Nurturance" factor in the female population. More than twice the symptomatology variance was explained by the factor scores for females than it was for males. The most important factorial predictors for psychiatric symptomatology were the "Power related hedonism" factor for males, and "Self oriented nurturance" for females. The results are discussed from theoretical and treatment perspectives
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Open-Source MUltiple Tests Corrections and FOrmatted Tables Software (MUFOS)
The p value statistic remains a ubiquitous indicator of the verisimilitude of experimental hypotheses. However, testing multiple hypotheses poses a problem as Type I error rate is inflated. Despite known solutions, this problem remains largely neglected for two reasons: 1) most data analysis tools offer limited multiple tests correction options; 2) the learning curve of existing tools requires hefty time investment. To address these concerns, we present a free, easy-to-use and convenient Software, built around established python libraries, that allows users to apply a MUltiple tests correction and get the results in a readily-understood, FOrmatted table (MUFOS) - https://github.com/nikbpetrov/mufos
Characterising within-hospital SARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves
Hospital outbreaks of COVID19 result in considerable mortality and disruption to healthcare services and yet little is known about transmission within this setting. We characterise within hospital transmission by combining viral genomic and epidemiological data using Bayesian modelling amongst 2181 patients and healthcare workers from a large UK NHS Trust. Transmission events were compared between Wave 1 (1st March to 25th July 2020) and Wave 2 (30th November 2020 to 24th January 2021). We show that staff-to-staff transmissions reduced from 31.6% to 12.9% of all infections. Patient-to-patient transmissions increased from 27.1% to 52.1%. 40%-50% of hospital-onset patient cases resulted in onward transmission compared to 4% of community-acquired cases. Control measures introduced during the pandemic likely reduced transmissions between healthcare workers but were insufficient to prevent increasing numbers of patient-to-patient transmissions. As hospital-acquired cases drive most onward transmission, earlier identification of nosocomial cases will be required to break hospital transmission chains
Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex disease that leads to motor neuron death. Despite heritability estimates of 52%, genome-wide association studies (GWASs) have discovered relatively few loci. We developed a machine learning approach called RefMap, which integrates functional genomics with GWAS summary statistics for gene discovery. With transcriptomic and epigenetic profiling of motor neurons derived from induced pluripotent stem cells (iPSCs), RefMap identified 690 ALS-associated genes that represent a 5-fold increase in recovered heritability. Extensive conservation, transcriptome, network, and rare variant analyses demonstrated the functional significance of candidate genes in healthy and diseased motor neurons and brain tissues. Genetic convergence between common and rare variation highlighted KANK1 as a new ALS gene. Reproducing KANK1 patient mutations in human neurons led to neurotoxicity and demonstrated that TDP-43 mislocalization, a hallmark pathology of ALS, is downstream of axonal dysfunction. RefMap can be readily applied to other complex diseases
Working in ministries or public organizations in Saudi Arabia : A study of career development and job satisfaction of the Saudi Arabian middle managers
Career development and job satisfaction studies carried out in developing countries are very limited in number. Saudi Arabia is one of those developing countries which appeared on the political scene quite recently, but striving hard to develop its human resources due to its heavy dependence on expatriate labour to initiate and execute its development plans. The genesis of the study began when General Civil Service Bureau officials noticed a large movement of employees from ministries to other sectors (i.e. public organizations and the private sector). The purpose of this dissertation is to examine and analyze the factors behind this movement and relate this to the studies of career development and job satisfaction. The position of government organizations in Saudi Arabia is rather unique. Most of their employees are drawn from Universities due to the regulations of the GCSB of compelling them to work in ministries for a period equivalent to that spent in their University education until graduation. This situation has prevented such graduates from choosing their own occupations and seem to hinder their career development. As a consequence, this study, not only analyzes career development and job satisfaction in Saudi Arabia, but (v) job satisfaction in Saudi Arabia, but also makes a comprehensive evaluation of economic, social and organisational environments which seem to have an effect of the occupational choice of the Saudis. We take the assumption that the ideology of free occupational choice is not properly applied in Saudi Arabia due to some cultural variables (e.g. nepotism and strong family ties). Hence, this thesis will develop a definition of the concept of occupational choice and career development and the process of personnel flow and the ways in which such movement can be influenced within the Saudi context. The study will be primarily concerned with middle managers in two types of organization - government ministries and public organizations. This will hopefully give a profile of the Saudi situation as far as occupational choice, career development and job satisfaction are concerned
In search of 'The people of La Manche': A comparative study of funerary practices in the Transmanche region during the late Neolithic and Early Bronze Age (250BC-1500BC)
This research project sets out to discover whether archaeological evidence dating between 2500 BC - 1500 BC from supposed funerary contexts in Kent, flanders and north-eastern Transmanche France is sufficient to make valid comparisons between social and cultural structures on either side of the short-sea Channel region. Evidence from the beginning of the period primarily comes in the form of the widespread Beaker phenomenon. Chapter 5 shows that this class of data is abundant in Kent but quite sparse in the Continental zones - most probably because it has not survived well. This problem also affects the human depositional evidence catalogued in Chapter 6, particularly in Fanders but also in north-eastern Transmanche France. This constricts comparative analysis, however, the abundant data from Kent means that general trends are still discernible. The quality and volume of data relating to the distribution, location, morphology and use of circular monuments in all three zones is far better - as demonstrated in Chapter 7 -mostly due to extensive aerial surveying over several decades. When the datasets are taken as a whole, it becomes possible to successfully apply various forms of comparative analyses. Most remarkably, this has revealed that some monuments apparently have encoded within them a sophisticated and potentially symbolically charged geometric shape. This, along with other less contentious evidence, demonstrates a level of conformity that strongly suggests a stratum of cultural homogeneity existed throughout the Transmanche region during the period 2500 BC - 1500 BC. The fact that such changes as are apparent seem to have developed simultaneously in each of the zones adds additional weight to the theory that contact throughout the Transmanche region was endemic. Even so, it may not have been continuous; there may actually have been times of relative isolation - the data is simply too course to eliminate such a possibility
Implementación de un algoritmo memético para resolver el problema de corte de materiales aplicado a la producción de barras de acero para hormigón
El país ha vivido durante los últimos años un aumento en el PBI que lo ha colocado como unos
de los principales países de la región. Este crecimiento se debe al aumento sostenido de la
producción en diversos sectores. Por cifras del Ministerio de Economía y Finanzas (MEF), el
sector de construcción, a cargo del Ministerio de Vivienda y Construcción representa uno de los
principales contribuyentes al PBI interno (MEF), con un aporte del 5% al indicador. Además, se
proyecta un crecimiento de 7% sostenido en los próximos años, por encima del promedio
nacional. Esto ayudará a impulsar los sectores primarios y secundarios relacionados. Así que se
vuelve prioritaria la elaboración de soluciones que aumenten la eficiencia en el consumo de
recursos a todo nivel.
En particular, este proyecto plantea abordar la producción de las barras de acero para hormigón
a nivel industrial. La actividad productiva por la cual el acero fundido es convertido en barras de
acero grandes, que serán a su vez cortadas en longitud para conseguir barras más pequeñas,
que son usadas en la manufactura y la construcción de edificios. Estas son las conocidas como
barras de acero para hormigón.
El proceso consta de dos partes principalmente:
● La elaboración de barras largas estándar por el proceso de colada y
● Una segunda fase de corte para obtener los productos finales, barras de acero para
hormigón, según el tamaño solicitado por los clientes.
Aunque la producción de la barra grande (primaria) se realiza en una línea de ensamblaje a partir
de acero fundido, lo que la vuelve virtualmente infinita y modificable en tamaño, las barras
pequeñas se elaboran a partir de un tamaño estándar que cada fábrica utiliza para la
manufactura.
Para elaborar la producción de barras estándar, se toman en cuenta las negociaciones entre los
ejecutivos de ventas y los clientes potenciales, obteniéndose requerimientos de producción.
Dichos requerimientos son luego incluidos en la programación del periodo tomando en cuenta la
disponibilidad de material (acero fundido). Debido a esto, aunque la primera etapa de corte es
limpia por la naturaleza de la fabricación, en la segunda se pueden producir desperdicios y
pérdidas, pues las barras grandes no siempre se utilizan al cien por ciento en la creación de
barras de acero para hormigón.
El problema entonces es de corte de materiales, el cual consiste en conseguir un número de
piezas de diferentes largos que deben ser cortadas de una fuente, de tal forma que se cumpla
con la demanda de largos y se produzcan optimizando una función objetivo. Por lo mencionado este trabajo de fin de carrera, plantea implementar un algoritmo memético
para resolver el problema de corte de materiales aplicado a la producción de barras de acero
para hormigón.
Objetivo General
Implementar un algoritmo memético para resolver el problema de corte de materiales aplicado a
la producción de barras de acero para hormigón.
Objetivos Específicos
O1. Definir la función objetivo a evaluar para los algoritmos genético y memético
O2. Diseñar un algoritmo memético como alternativa de solución para el problema de corte de
materiales unidimensional de barras de acero para hormigón
O3. Adaptar un algoritmo genético obtenido de la revisión de la literatura como alternativa de
solución para el problema de corte de materiales de barras de acero para hormigón
O4. Implementar los algoritmos propuestos en un módulo de ejecución de algoritmos
O5. Realizar experimentación mediante pruebas numéricas para comparar el desempeño entre
ambas alternativas de solución
Brain electrical traits of logical validity
p. 1-13Neuroscience has studied deductive reasoning over the last 20 years under the assumption that deductive inferences are not only de jure but also de facto distinct from other forms of inference. The objective of this research is to verify if logically valid deductions leave any cerebral electrical trait that is distinct from the trait left by non-valid deductions. 23 subjects with an average age of 20.35 years were registered with MEG and placed into a two conditions paradigm (100 trials for each condition) which each presented the exact same relational complexity (same variables and content) but had distinct logical complexity. Both conditions show the same electromagnetic components (P3, N4) in the early temporal window (250–525 ms) and P6 in the late temporal window (500–775 ms). The significant activity in both valid and invalid conditions is found in sensors from medial prefrontal regions, probably corresponding to the ACC or to the medial prefrontal cortex. The amplitude and intensity of valid deductions is significantly lower in both temporal windows (p = 0.0003). The reaction time was 54.37% slower in the valid condition. Validity leaves a minimal but measurable hypoactive electrical trait in brain processing. The minor electrical demand is attributable to the recursive and automatable character of valid deductions, suggesting a physical indicator of computational deductive properties. It is hypothesized that all valid deductions are recursive and hypoactive.S
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