5,597 research outputs found

    Endogenous measures for contextualising large-scale social phenomena: a corpus-based method for mediated public discourse

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    This work presents an interdisciplinary methodology for developing endogenous measures of group membership through analysis of pervasive linguistic patterns in public discourse. Focusing on political discourse, this work critiques the conventional approach to the study of political participation, which is premised on decontextualised, exogenous measures to characterise groups. Considering the theoretical and empirical weaknesses of decontextualised approaches to large-scale social phenomena, this work suggests that contextualisation using endogenous measures might provide a complementary perspective to mitigate such weaknesses. This work develops a sociomaterial perspective on political participation in mediated discourse as affiliatory action performed through language. While the affiliatory function of language is often performed consciously (such as statements of identity), this work is concerned with unconscious features (such as patterns in lexis and grammar). This work argues that pervasive patterns in such features that emerge through socialisation are resistant to change and manipulation, and thus might serve as endogenous measures of sociopolitical contexts, and thus of groups. In terms of method, the work takes a corpus-based approach to the analysis of data from the Twitter messaging service whereby patterns in users’ speech are examined statistically in order to trace potential community membership. The method is applied in the US state of Michigan during the second half of 2018—6 November having been the date of midterm (i.e. non-Presidential) elections in the United States. The corpus is assembled from the original posts of 5,889 users, who are nominally geolocalised to 417 municipalities. These users are clustered according to pervasive language features. Comparing the linguistic clusters according to the municipalities they represent finds that there are regular sociodemographic differentials across clusters. This is understood as an indication of social structure, suggesting that endogenous measures derived from pervasive patterns in language may indeed offer a complementary, contextualised perspective on large-scale social phenomena

    Scaling up integrated photonic reservoirs towards low-power high-bandwidth computing

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    Grasping nothing: a study of minimal ontologies and the sense of music

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    If music were to have a proper sense – one in which it is truly given – one might reasonably place this in sound and aurality. I contend, however, that no such sense exists; rather, the sense of music takes place, and it does so with the impossible. To this end, this thesis – which is a work of philosophy and music – advances an ontology of the impossible (i.e., it thinks the being of what, properly speaking, can have no being) and considers its implications for music, articulating how ontological aporias – of the event, of thinking the absolute, and of sovereignty’s dismemberment – imply senses of music that are anterior to sound. John Cage’s Silent Prayer, a nonwork he never composed, compels a rerethinking of silence on the basis of its contradictory status of existence; Florian Hecker et al.’s Speculative Solution offers a basis for thinking absolute music anew to the precise extent that it is a discourse of meaninglessness; and Manfred Werder’s [yearn] pieces exhibit exemplarily that music’s sense depends on the possibility of its counterfeiting. Inso-much as these accounts produce musical senses that take the place of sound, they are also understood to be performances of these pieces. Here, then, thought is music’s organon and its instrument

    Composable code generation for high order, compatible finite element methods

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    It has been widely recognised in the HPC communities across the world, that exploiting modern computer architectures, including exascale machines, to a full extent requires software commu- nities to adapt their algorithms. Computational methods with a high ratio of floating point op- erations to bandwidth are favorable. For solving partial differential equations, which can model many physical problems, high order finite element methods can calculate approximations with a high efficiency when a good solver is employed. Matrix-free algorithms solve the corresponding equations with a high arithmetic intensity. Vectorisation speeds up the operations by calculating one instruction on multiple data elements. Another recent development for solving partial differential are compatible (mimetic) finite ele- ment methods. In particular with application to geophysical flows, compatible discretisations ex- hibit desired numerical properties required for accurate approximations. Among others, this has been recognised by the UK Met office and their new dynamical core for weather and climate fore- casting is built on a compatible discretisation. Hybridisation has been proven to be an efficient solver for the corresponding equation systems, because it removes some inter-elemental coupling and localises expensive operations. This thesis combines the recent advances on vectorised, matrix-free, high order finite element methods in the HPC community on the one hand and hybridised, compatible discretisations in the geophysical community on the other. In previous work, a code generation framework has been developed to support the localised linear algebra required for hybridisation. First, the framework is adapted to support vectorisation and further, extended so that the equations can be solved fully matrix-free. Promising performance results are completing the thesis.Open Acces

    Investigation of microparticle behavior in Newtonian, viscoelastic, and shear-thickening flows in straight microchannels

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    Sorting and separation of small substances such as cells, microorganisms, and micro- and nano-particles from a heterogeneous mixture is a common sample preparation step in many areas of biology, biotechnology, and medicine. Portability and inexpensive design of microfluidic-based sorting systems have benefited many of these biomedical applications. Accordingly, we have investigated microparticle hydrodynamics in fluids with various rheological behaviors (i.e., Newtonian, shear-thinning viscoelastic and shear-thickening non-Newtonian) flowing in straight microchannels. Numerical models were developed to simulate particles trajectories in Newtonian water and shear-thinning polyethylene oxide (PEO) solutions. The validated models were then used to perform numerical parametric studies and non-dimensional analysis on the Newtonian inertia-magnetic and shear-thinning elasto-inertal focusing regimes. Finally, the straight microfluidic device that was tested for Newtonian water and shear-thinning viscoelastic PEO solution, were adopted to experimentally study microparticle behavior in SiO2/Water shear-thickening nanofluid

    FiabilitĂ© de l’underfill et estimation de la durĂ©e de vie d’assemblages microĂ©lectroniques

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    Abstract : In order to protect the interconnections in flip-chip packages, an underfill material layer is used to fill the volumes and provide mechanical support between the silicon chip and the substrate. Due to the chip corner geometry and the mismatch of coefficient of thermal expansion (CTE), the underfill suffers from a stress concentration at the chip corners when the temperature is lower than the curing temperature. This stress concentration leads to subsequent mechanical failures in flip-chip packages, such as chip-underfill interfacial delamination and underfill cracking. Local stresses and strains are the most important parameters for understanding the mechanism of underfill failures. As a result, the industry currently relies on the finite element method (FEM) to calculate the stress components, but the FEM may not be accurate enough compared to the actual stresses in underfill. FEM simulations require a careful consideration of important geometrical details and material properties. This thesis proposes a modeling approach that can accurately estimate the underfill delamination areas and crack trajectories, with the following three objectives. The first objective was to develop an experimental technique capable of measuring underfill deformations around the chip corner region. This technique combined confocal microscopy and the digital image correlation (DIC) method to enable tri-dimensional strain measurements at different temperatures, and was named the confocal-DIC technique. This techique was first validated by a theoretical analysis on thermal strains. In a test component similar to a flip-chip package, the strain distribution obtained by the FEM model was in good agreement with the results measured by the confocal-DIC technique, with relative errors less than 20% at chip corners. Then, the second objective was to measure the strain near a crack in underfills. Artificial cracks with lengths of 160 ÎŒm and 640 ÎŒm were fabricated from the chip corner along the 45° diagonal direction. The confocal-DIC-measured maximum hoop strains and first principal strains were located at the crack front area for both the 160 ÎŒm and 640 ÎŒm cracks. A crack model was developed using the extended finite element method (XFEM), and the strain distribution in the simulation had the same trend as the experimental results. The distribution of hoop strains were in good agreement with the measured values, when the model element size was smaller than 22 ÎŒm to capture the strong strain gradient near the crack tip. The third objective was to propose a modeling approach for underfill delamination and cracking with the effects of manufacturing variables. A deep thermal cycling test was performed on 13 test cells to obtain the reference chip-underfill delamination areas and crack profiles. An artificial neural network (ANN) was trained to relate the effects of manufacturing variables and the number of cycles to first delamination of each cell. The predicted numbers of cycles for all 6 cells in the test dataset were located in the intervals of experimental observations. The growth of delamination was carried out on FEM by evaluating the strain energy amplitude at the interface elements between the chip and underfill. For 5 out of 6 cells in validation, the delamination growth model was consistent with the experimental observations. The cracks in bulk underfill were modelled by XFEM without predefined paths. The directions of edge cracks were in good agreement with the experimental observations, with an error of less than 2.5°. This approach met the goal of the thesis of estimating the underfill initial delamination, areas of delamination and crack paths in actual industrial flip-chip assemblies.Afin de protĂ©ger les interconnexions dans les assemblages, une couche de matĂ©riau d’underfill est utilisĂ©e pour remplir le volume et fournir un support mĂ©canique entre la puce de silicium et le substrat. En raison de la gĂ©omĂ©trie du coin de puce et de l’écart du coefficient de dilatation thermique (CTE), l’underfill souffre d’une concentration de contraintes dans les coins lorsque la tempĂ©rature est infĂ©rieure Ă  la tempĂ©rature de cuisson. Cette concentration de contraintes conduit Ă  des dĂ©faillances mĂ©caniques dans les encapsulations de flip-chip, telles que la dĂ©lamination interfaciale puce-underfill et la fissuration d’underfill. Les contraintes et dĂ©formations locales sont les paramĂštres les plus importants pour comprendre le mĂ©canisme des ruptures de l’underfill. En consĂ©quent, l’industrie utilise actuellement la mĂ©thode des Ă©lĂ©ments finis (EF) pour calculer les composantes de la contrainte, qui ne sont pas assez prĂ©cises par rapport aux contraintes actuelles dans l’underfill. Ces simulations nĂ©cessitent un examen minutieux de dĂ©tails gĂ©omĂ©triques importants et des propriĂ©tĂ©s des matĂ©riaux. Cette thĂšse vise Ă  proposer une approche de modĂ©lisation permettant d’estimer avec prĂ©cision les zones de dĂ©lamination et les trajectoires des fissures dans l’underfill, avec les trois objectifs suivants. Le premier objectif est de mettre au point une technique expĂ©rimentale capable de mesurer la dĂ©formation de l’underfill dans la rĂ©gion du coin de puce. Cette technique, combine la microscopie confocale et la mĂ©thode de corrĂ©lation des images numĂ©riques (DIC) pour permettre des mesures tridimensionnelles des dĂ©formations Ă  diffĂ©rentes tempĂ©ratures, et a Ă©tĂ© nommĂ©e le technique confocale-DIC. Cette technique a d’abord Ă©tĂ© validĂ©e par une analyse thĂ©orique en dĂ©formation thermique. Dans un Ă©chantillon similaire Ă  un flip-chip, la distribution de la dĂ©formation obtenues par le modĂšle EF Ă©tait en bon accord avec les rĂ©sultats de la technique confocal-DIC, avec des erreurs relatives infĂ©rieures Ă  20% au coin de puce. Ensuite, le second objectif est de mesurer la dĂ©formation autour d’une fissure dans l’underfill. Des fissures artificielles d’une longueuer de 160 ÎŒm et 640 ÎŒm ont Ă©tĂ© fabriquĂ©es dans l’underfill vers la direction diagonale de 45°. Les dĂ©formations circonfĂ©rentielles maximales et principale maximale Ă©taient situĂ©es aux pointes des fissures correspondantes. Un modĂšle de fissure a Ă©tĂ© dĂ©veloppĂ© en utilisant la mĂ©thode des Ă©lĂ©ments finis Ă©tendue (XFEM), et la distribution des contraintes dans la simuation a montrĂ© la mĂȘme tendance que les rĂ©sultats expĂ©rimentaux. La distribution des dĂ©formations circonfĂ©rentielles maximales Ă©tait en bon accord avec les valeurs mesurĂ©es lorsque la taille des Ă©lĂ©ments Ă©tait plus petite que 22 ÎŒm, assez petit pour capturer le grand gradient de dĂ©formation prĂšs de la pointe de fissure. Le troisiĂšme objectif Ă©tait d’apporter une approche de modĂ©lisation de la dĂ©lamination et de la fissuration de l’underfill avec les effets des variables de fabrication. Un test de cyclage thermique a d’abord Ă©tĂ© effectuĂ© sur 13 cellules pour obtenir les zones dĂ©laminĂ©es entre la puce et l’underfill, et les profils de fissures dans l’underfill, comme rĂ©fĂ©rence. Un rĂ©seau neuronal artificiel (ANN) a Ă©tĂ© formĂ© pour Ă©tablir une liaison entre les effets des variables de fabrication et le nombre de cycles Ă  la dĂ©lamination pour chaque cellule. Les nombres de cycles prĂ©dits pour les 6 cellules de l’ensemble de test Ă©taient situĂ©s dans les intervalles d’observations expĂ©rimentaux. La croissance de la dĂ©lamination a Ă©tĂ© rĂ©alisĂ©e par l’EF en Ă©valuant l’énergie de la dĂ©formation au niveau des Ă©lĂ©ments interfaciaux entre la puce et l’underfill. Pour 5 des 6 cellules de la validation, le modĂšle de croissance du dĂ©laminage Ă©tait conforme aux observations expĂ©rimentales. Les fissures dans l’underfill ont Ă©tĂ© modĂ©lisĂ©es par XFEM sans chemins prĂ©dĂ©finis. Les directions des fissures de bord Ă©taient en bon accord avec les observations expĂ©rimentales, avec une erreur infĂ©rieure Ă  2,5°. Cette approche a rĂ©pondu Ă  la problĂ©matique qui consiste Ă  estimer l’initiation des dĂ©lamination, les zones de dĂ©lamination et les trajectoires de fissures dans l’underfill pour des flip-chips industriels

    Machine learning for managing structured and semi-structured data

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    As the digitalization of private, commercial, and public sectors advances rapidly, an increasing amount of data is becoming available. In order to gain insights or knowledge from these enormous amounts of raw data, a deep analysis is essential. The immense volume requires highly automated processes with minimal manual interaction. In recent years, machine learning methods have taken on a central role in this task. In addition to the individual data points, their interrelationships often play a decisive role, e.g. whether two patients are related to each other or whether they are treated by the same physician. Hence, relational learning is an important branch of research, which studies how to harness this explicitly available structural information between different data points. Recently, graph neural networks have gained importance. These can be considered an extension of convolutional neural networks from regular grids to general (irregular) graphs. Knowledge graphs play an essential role in representing facts about entities in a machine-readable way. While great efforts are made to store as many facts as possible in these graphs, they often remain incomplete, i.e., true facts are missing. Manual verification and expansion of the graphs is becoming increasingly difficult due to the large volume of data and must therefore be assisted or substituted by automated procedures which predict missing facts. The field of knowledge graph completion can be roughly divided into two categories: Link Prediction and Entity Alignment. In Link Prediction, machine learning models are trained to predict unknown facts between entities based on the known facts. Entity Alignment aims at identifying shared entities between graphs in order to link several such knowledge graphs based on some provided seed alignment pairs. In this thesis, we present important advances in the field of knowledge graph completion. For Entity Alignment, we show how to reduce the number of required seed alignments while maintaining performance by novel active learning techniques. We also discuss the power of textual features and show that graph-neural-network-based methods have difficulties with noisy alignment data. For Link Prediction, we demonstrate how to improve the prediction for unknown entities at training time by exploiting additional metadata on individual statements, often available in modern graphs. Supported with results from a large-scale experimental study, we present an analysis of the effect of individual components of machine learning models, e.g., the interaction function or loss criterion, on the task of link prediction. We also introduce a software library that simplifies the implementation and study of such components and makes them accessible to a wide research community, ranging from relational learning researchers to applied fields, such as life sciences. Finally, we propose a novel metric for evaluating ranking results, as used for both completion tasks. It allows for easier interpretation and comparison, especially in cases with different numbers of ranking candidates, as encountered in the de-facto standard evaluation protocols for both tasks.Mit der rasant fortschreitenden Digitalisierung des privaten, kommerziellen und öffentlichen Sektors werden immer grĂ¶ĂŸere Datenmengen verfĂŒgbar. Um aus diesen enormen Mengen an Rohdaten Erkenntnisse oder Wissen zu gewinnen, ist eine tiefgehende Analyse unerlĂ€sslich. Das immense Volumen erfordert hochautomatisierte Prozesse mit minimaler manueller Interaktion. In den letzten Jahren haben Methoden des maschinellen Lernens eine zentrale Rolle bei dieser Aufgabe eingenommen. Neben den einzelnen Datenpunkten spielen oft auch deren ZusammenhĂ€nge eine entscheidende Rolle, z.B. ob zwei Patienten miteinander verwandt sind oder ob sie vom selben Arzt behandelt werden. Daher ist das relationale Lernen ein wichtiger Forschungszweig, der untersucht, wie diese explizit verfĂŒgbaren strukturellen Informationen zwischen verschiedenen Datenpunkten nutzbar gemacht werden können. In letzter Zeit haben Graph Neural Networks an Bedeutung gewonnen. Diese können als eine Erweiterung von CNNs von regelmĂ€ĂŸigen Gittern auf allgemeine (unregelmĂ€ĂŸige) Graphen betrachtet werden. Wissensgraphen spielen eine wesentliche Rolle bei der Darstellung von Fakten ĂŒber EntitĂ€ten in maschinenlesbaren Form. Obwohl große Anstrengungen unternommen werden, so viele Fakten wie möglich in diesen Graphen zu speichern, bleiben sie oft unvollstĂ€ndig, d. h. es fehlen Fakten. Die manuelle ÜberprĂŒfung und Erweiterung der Graphen wird aufgrund der großen Datenmengen immer schwieriger und muss daher durch automatisierte Verfahren unterstĂŒtzt oder ersetzt werden, die fehlende Fakten vorhersagen. Das Gebiet der WissensgraphenvervollstĂ€ndigung lĂ€sst sich grob in zwei Kategorien einteilen: Link Prediction und Entity Alignment. Bei der Link Prediction werden maschinelle Lernmodelle trainiert, um unbekannte Fakten zwischen EntitĂ€ten auf der Grundlage der bekannten Fakten vorherzusagen. Entity Alignment zielt darauf ab, gemeinsame EntitĂ€ten zwischen Graphen zu identifizieren, um mehrere solcher Wissensgraphen auf der Grundlage einiger vorgegebener Paare zu verknĂŒpfen. In dieser Arbeit stellen wir wichtige Fortschritte auf dem Gebiet der VervollstĂ€ndigung von Wissensgraphen vor. FĂŒr das Entity Alignment zeigen wir, wie die Anzahl der benötigten Paare reduziert werden kann, wĂ€hrend die Leistung durch neuartige aktive Lerntechniken erhalten bleibt. Wir erörtern auch die LeistungsfĂ€higkeit von Textmerkmalen und zeigen, dass auf Graph-Neural-Networks basierende Methoden Schwierigkeiten mit verrauschten Paar-Daten haben. FĂŒr die Link Prediction demonstrieren wir, wie die Vorhersage fĂŒr unbekannte EntitĂ€ten zur Trainingszeit verbessert werden kann, indem zusĂ€tzliche Metadaten zu einzelnen Aussagen genutzt werden, die oft in modernen Graphen verfĂŒgbar sind. GestĂŒtzt auf Ergebnisse einer groß angelegten experimentellen Studie prĂ€sentieren wir eine Analyse der Auswirkungen einzelner Komponenten von Modellen des maschinellen Lernens, z. B. der Interaktionsfunktion oder des Verlustkriteriums, auf die Aufgabe der Link Prediction. Außerdem stellen wir eine Softwarebibliothek vor, die die Implementierung und Untersuchung solcher Komponenten vereinfacht und sie einer breiten Forschungsgemeinschaft zugĂ€nglich macht, die von Forschern im Bereich des relationalen Lernens bis hin zu angewandten Bereichen wie den Biowissenschaften reicht. Schließlich schlagen wir eine neuartige Metrik fĂŒr die Bewertung von Ranking-Ergebnissen vor, wie sie fĂŒr beide Aufgaben verwendet wird. Sie ermöglicht eine einfachere Interpretation und einen leichteren Vergleich, insbesondere in FĂ€llen mit einer unterschiedlichen Anzahl von Kandidaten, wie sie in den de-facto Standardbewertungsprotokollen fĂŒr beide Aufgaben vorkommen

    Unraveling the effect of sex on human genetic architecture

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    Sex is arguably the most important differentiating characteristic in most mammalian species, separating populations into different groups, with varying behaviors, morphologies, and physiologies based on their complement of sex chromosomes, amongst other factors. In humans, despite males and females sharing nearly identical genomes, there are differences between the sexes in complex traits and in the risk of a wide array of diseases. Sex provides the genome with a distinct hormonal milieu, differential gene expression, and environmental pressures arising from gender societal roles. This thus poses the possibility of observing gene by sex (GxS) interactions between the sexes that may contribute to some of the phenotypic differences observed. In recent years, there has been growing evidence of GxS, with common genetic variation presenting different effects on males and females. These studies have however been limited in regards to the number of traits studied and/or statistical power. Understanding sex differences in genetic architecture is of great importance as this could lead to improved understanding of potential differences in underlying biological pathways and disease etiology between the sexes and in turn help inform personalised treatments and precision medicine. In this thesis we provide insights into both the scope and mechanism of GxS across the genome of circa 450,000 individuals of European ancestry and 530 complex traits in the UK Biobank. We found small yet widespread differences in genetic architecture across traits through the calculation of sex-specific heritability, genetic correlations, and sex-stratified genome-wide association studies (GWAS). We further investigated whether sex-agnostic (non-stratified) efforts could potentially be missing information of interest, including sex-specific trait-relevant loci and increased phenotype prediction accuracies. Finally, we studied the potential functional role of sex differences in genetic architecture through sex biased expression quantitative trait loci (eQTL) and gene-level analyses. Overall, this study marks a broad examination of the genetics of sex differences. Our findings parallel previous reports, suggesting the presence of sexual genetic heterogeneity across complex traits of generally modest magnitude. Furthermore, our results suggest the need to consider sex-stratified analyses in future studies in order to shed light into possible sex-specific molecular mechanisms
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