Etiology-based classification of brain white matter hyperintensity on magnetic resonance imaging

Brain white matter lesions found upon magnetic resonance imaging are often observed in psychiatric or neurological patients. Individuals with these lesions present a more significant cognitive impairment when compared with individuals without them. We propose a computerized method to distinguish tissue containing white matter lesions of different etiologies (e.g., demyelinating or ischemic) using texture-based classifiers. Texture attributes were extracted from manually selected regions of interest and used to train and test supervised classifiers. Experiments were conducted to evaluate texture attribute discrimination and classifiers' performances. The most discriminating texture attributes were obtained from the gray-level histogram and from the co-occurrence matrix. The best classifier was the support vector machine, which achieved an accuracy of 87.9% in distinguishing lesions with different etiologies and an accuracy of 99.29% in distinguishing normal white matter from white matter lesions. (c) 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)21COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPnão tem2012/21826-1; 2013/07559-

Computational Intelligence Methods for Medical Image Understanding, Visualization, and Interaction

Ph.DDOCTOR OF PHILOSOPH

Histopathological image analysis : a review

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe

3D Classification of Power Line Scene Using Airborne Lidar Data

Failure to adequately maintain vegetation within a power line corridor has been identified as a main cause of the August 14, 2003 electric power blackout. Such that, timely and accurate corridor mapping and monitoring are indispensible to mitigate such disaster. Moreover, airborne LiDAR (Light Detection And Ranging) has been recently introduced and widely utilized in industries and academies thanks to its potential to automate the data processing for scene analysis including power line corridor mapping. However, today’s corridor mapping practice using LiDAR in industries still remains an expensive manual process that is not suitable for the large-scale, rapid commercial compilation of corridor maps. Additionally, in academies only few studies have developed algorithms capable of recognizing corridor objects in the power line scene, which are mostly based on 2-dimensional classification. Thus, the objective of this dissertation is to develop a 3-dimensional classification system which is able to automatically identify key objects in the power line corridor from large-scale LiDAR data. This dissertation introduces new features for power structures, especially for the electric pylon, and existing features which are derived through diverse piecewise (i.e., point, line and plane) feature extraction, and then constructs a classification model pool by building individual models according to the piecewise feature sets and diverse voltage training samples using Random Forests. Finally, this dissertation proposes a Multiple Classifier System (MCS) which provides an optimal committee of models from the model pool for classification of new incoming power line scene. The proposed MCS has been tested on a power line corridor where medium voltage transmission lines (115 kV and 230 kV) pass. The classification results based on the MCS applied by optimally selecting the pre-built classification models according to the voltage type of the test corridor demonstrate a good accuracy (89.07%) and computationally effective time cost (approximately 4 hours/km) without additional training fees

From source to target and back: symmetric bi-directional adaptive GAN

The effectiveness of generative adversarial approaches in producing images according to a specific style or visual domain has recently opened new directions to solve the unsupervised domain adaptation problem. It has been shown that source labeled images can be modified to mimic target samples making it possible to train directly a classifier in the target domain, despite the original lack of annotated data. Inverse mappings from the target to the source domain have also been evaluated but only passing through adapted feature spaces, thus without new image generation. In this paper we propose to better exploit the potential of generative adversarial networks for adaptation by introducing a novel symmetric mapping among domains. We jointly optimize bi-directional image transformations combining them with target self-labeling. Moreover we define a new class consistency loss that aligns the generators in the two directions imposing to conserve the class identity of an image passing through both domain mappings. A detailed qualitative and quantitative analysis of the reconstructed images confirm the power of our approach. By integrating the two domain specific classifiers obtained with our bi-directional network we exceed previous state-of-the-art unsupervised adaptation results on four different benchmark datasets