Methods for monitoring the human circadian rhythm in free-living

Our internal clock, the circadian clock, determines at which time we have our best cognitive abilities, are physically strongest, and when we are tired. Circadian clock phase is influenced primarily through exposure to light. A direct pathway from the eyes to the suprachiasmatic nucleus, where the circadian clock resides, is used to synchronise the circadian clock to external light-dark cycles. In modern society, with the ability to work anywhere at anytime and a full social agenda, many struggle to keep internal and external clocks synchronised. Living against our circadian clock makes us less efficient and poses serious health impact, especially when exercised over a long period of time, e.g. in shift workers. Assessing circadian clock phase is a cumbersome and uncomfortable task. A common method, dim light melatonin onset testing, requires a series of eight saliva samples taken in hourly intervals while the subject stays in dim light condition from 5 hours before until 2 hours past their habitual bedtime. At the same time, sensor-rich smartphones have become widely available and wearable computing is on the rise. The hypothesis of this thesis is that smartphones and wearables can be used to record sensor data to monitor human circadian rhythms in free-living. To test this hypothesis, we conducted research on specialised wearable hardware and smartphones to record relevant data, and developed algorithms to monitor circadian clock phase in free-living. We first introduce our smart eyeglasses concept, which can be personalised to the wearers head and 3D-printed. Furthermore, hardware was integrated into the eyewear to recognise typical activities of daily living (ADLs). A light sensor integrated into the eyeglasses bridge was used to detect screen use. In addition to wearables, we also investigate if sleep-wake patterns can be revealed from smartphone context information. We introduce novel methods to detect sleep opportunity, which incorporate expert knowledge to filter and fuse classifier outputs. Furthermore, we estimate light exposure from smartphone sensor and weather in- formation. We applied the Kronauer model to compare the phase shift resulting from head light measurements, wrist measurements, and smartphone estimations. We found it was possible to monitor circadian phase shift from light estimation based on smartphone sensor and weather information with a weekly error of 32±17min, which outperformed wrist measurements in 11 out of 12 participants. Sleep could be detected from smartphone use with an onset error of 40±48 min and wake error of 42±57 min. Screen use could be detected smart eyeglasses with 0.9 ROC AUC for ambient light intensities below 200lux. Nine clusters of ADLs were distinguished using Gaussian mixture models with an average accuracy of 77%. In conclusion, a combination of the proposed smartphones and smart eyeglasses applications could support users in synchronising their circadian clock to the external clocks, thus living a healthier lifestyle

Computational Personalization through Physical and Aesthetic Featured Digital Fabrication

Thesis (Master of Science in Informatics)--University of Tsukuba, no. 41269, 2019.3.2

Advanced Signal Processing in Wearable Sensors for Health Monitoring

Smart, wearables devices on a miniature scale are becoming increasingly widely available, typically in the form of smart watches and other connected devices. Consequently, devices to assist in measurements such as electroencephalography (EEG), electrocardiogram (ECG), electromyography (EMG), blood pressure (BP), photoplethysmography (PPG), heart rhythm, respiration rate, apnoea, and motion detection are becoming more available, and play a significant role in healthcare monitoring. The industry is placing great emphasis on making these devices and technologies available on smart devices such as phones and watches. Such measurements are clinically and scientifically useful for real-time monitoring, long-term care, and diagnosis and therapeutic techniques. However, a pertaining issue is that recorded data are usually noisy, contain many artefacts, and are affected by external factors such as movements and physical conditions. In order to obtain accurate and meaningful indicators, the signal has to be processed and conditioned such that the measurements are accurate and free from noise and disturbances. In this context, many researchers have utilized recent technological advances in wearable sensors and signal processing to develop smart and accurate wearable devices for clinical applications. The processing and analysis of physiological signals is a key issue for these smart wearable devices. Consequently, ongoing work in this field of study includes research on filtration, quality checking, signal transformation and decomposition, feature extraction and, most recently, machine learning-based methods

Display computers

A Display Computer (DC) is an everyday object: Display Computer = Display + Computer. The “Display” part is the standard viewing surface found on everyday objects that conveys information or art. The “Computer” is found on the same everyday object; but by its ubiquitous nature, it will be relatively unnoticeable by the DC user, as it is manufactured “in the margins”. A DC may be mobile, moving with us as part of the everyday object we are using. DCs will be ubiquitous: “effectively invisible”, available at a glance, and seamlessly integrated into the environment. A DC should be an example of Weiser’s calm technology: encalming to the user, providing peripheral awareness without information overload. A DC should provide unremarkable computing in support of our daily routines in life. The nbaCub (nightly bedtime ambient Cues utility buddy) prototype illustrates a sample application of how DCs can be useful in the everyday environment of the home of the future. Embedding a computer into a toy, such that the display is the only visible portion, can present many opportunities for seamless and nontraditional uses of computing technology for our youngest user community. A field study was conducted in the home environment of a five-year old child over ten consecutive weeks as an informal, proof of concept of what Display Computers for children can look like and be used for in the near future. The personalized nbaCub provided lightweight, ambient information during the necessary daily routines of preparing for bed (evening routine) and preparing to go to school (morning routine). To further understand the child’s progress towards learning abstract concepts of time passage and routines, a novel “test by design” activity was included. Here, the role of the subject changed to primary designer/director. Final post-testing showed the subject knew both morning and bedtime routines very well and correctly answered seven of eight questions based on abstract images of time passage. Thus, the subject was in the process of learning the more abstract concept of time passage, but was not totally comfortable with the idea at the end of the study

Data and the city – accessibility and openness. a cybersalon paper on open data

This paper showcases examples of bottom–up open data and smart city applications and identifies lessons for future such efforts. Examples include Changify, a neighbourhood-based platform for residents, businesses, and companies; Open Sensors, which provides APIs to help businesses, startups, and individuals develop applications for the Internet of Things; and Cybersalon’s Hackney Treasures. a location-based mobile app that uses Wikipedia entries geolocated in Hackney borough to map notable local residents. Other experiments with sensors and open data by Cybersalon members include Ilze Black and Nanda Khaorapapong's The Breather, a "breathing" balloon that uses high-end, sophisticated sensors to make air quality visible; and James Moulding's AirPublic, which measures pollution levels. Based on Cybersalon's experience to date, getting data to the people is difficult, circuitous, and slow, requiring an intricate process of leadership, public relations, and perseverance. Although there are myriad tools and initiatives, there is no one solution for the actual transfer of that data