M2U-net: Effective and efficient retinal vessel segmentation for real-world applications

In this paper, we present a novel neural network architecture for retinal vessel segmentation that improves over the state of the art on two benchmark datasets, is the first to run in real time on high resolution images, and its small memory and processing requirements make it deployable in mobile and embedded systems. The M2U-Net has a new encoder-decoder architecture that is inspired by the U-Net. It adds pretrained components of MobileNetV2 in the encoder part and novel contractive bottleneck blocks in the decoder part that, combined with bilinear upsampling, drastically reduce the parameter count to 0.55M compared to 31.03M in the original U-Net. We have evaluated its performance against a wide body of previously published results on three public datasets. On two of them, the M2U-Net achieves new state-of-the-art performance by a considerable margin. When implemented on a GPU, our method is the first to achieve real-time inference speeds on high-resolution fundus images. We also implemented our proposed network on an ARM-based embedded system where it segments images in between 0.6 and 15 sec, depending on the resolution. Thus, the M2U-Net enables a number of applications of retinal vessel structure extraction, such as early diagnosis of eye diseases, retinal biometric authentication systems, and robot assisted microsurgery

Body language, security and e-commerce

Security is becoming an increasingly more important concern both at the desktop level and at the network level. This article discusses several approaches to authenticating individuals through the use of biometric devices. While libraries might not implement such devices, they may appear in the near future of desktop computing, particularly for access to institutional computers or for access to sensitive information. Other approaches to computer security focus on protecting the contents of electronic transmissions and verification of individual users. After a brief overview of encryption technologies, the article examines public-key cryptography which is getting a lot of attention in the business world in what is called public key infrastructure. It also examines other efforts, such as IBM’s Cryptolope, the Secure Sockets Layer of Web browsers, and Digital Certificates and Signatures. Secure electronic transmissions are an important condition for conducting business on the Net. These business transactions are not limited to purchase orders, invoices, and contracts. This could become an important tool for information vendors and publishers to control access to the electronic resources they license. As license negotiators and contract administrators, librarians need to be aware of what is happening in these new technologies and the impact that will have on their operations

On the Use of XML in Medical Imaging Web-Based Applications

The rapid growth of digital technology in medical fields over recent years has increased the need for applications able to manage patient medical records, imaging data, and chart information. Web-based applications are implemented with the purpose to link digital databases, storage and transmission protocols, management of large volumes of data and security concepts, allowing the possibility to read, analyze, and even diagnose remotely from the medical center where the information was acquired. The objective of this paper is to analyze the use of the Extensible Markup Language (XML) language in web-based applications that aid in diagnosis or treatment of patients, considering how this protocol allows indexing and exchanging the huge amount of information associated with each medical case. The purpose of this paper is to point out the main advantages and drawbacks of the XML technology in order to provide key ideas for future web-based applicationsPeer ReviewedPostprint (author's final draft

Deep Neural Ensemble for Retinal Vessel Segmentation in Fundus Images towards Achieving Label-free Angiography

Automated segmentation of retinal blood vessels in label-free fundus images entails a pivotal role in computed aided diagnosis of ophthalmic pathologies, viz., diabetic retinopathy, hypertensive disorders and cardiovascular diseases. The challenge remains active in medical image analysis research due to varied distribution of blood vessels, which manifest variations in their dimensions of physical appearance against a noisy background. In this paper we formulate the segmentation challenge as a classification task. Specifically, we employ unsupervised hierarchical feature learning using ensemble of two level of sparsely trained denoised stacked autoencoder. First level training with bootstrap samples ensures decoupling and second level ensemble formed by different network architectures ensures architectural revision. We show that ensemble training of auto-encoders fosters diversity in learning dictionary of visual kernels for vessel segmentation. SoftMax classifier is used for fine tuning each member auto-encoder and multiple strategies are explored for 2-level fusion of ensemble members. On DRIVE dataset, we achieve maximum average accuracy of 95.33\% with an impressively low standard deviation of 0.003 and Kappa agreement coefficient of 0.708 . Comparison with other major algorithms substantiates the high efficacy of our model.Comment: Accepted as a conference paper at IEEE EMBC, 201

Image database system for glaucoma diagnosis support

Tato práce popisuje přehled standardních a pokročilých metod používaných k diagnose glaukomu v ranném stádiu. Na základě teoretických poznatků je implementován internetově orientovaný informační systém pro oční lékaře, který má tři hlavní cíle. Prvním cílem je možnost sdílení osobních dat konkrétního pacienta bez nutnosti posílat tato data internetem. Druhým cílem je vytvořit účet pacienta založený na kompletním očním vyšetření. Posledním cílem je aplikovat algoritmus pro registraci intenzitního a barevného fundus obrazu a na jeho základě vytvořit internetově orientovanou tři-dimenzionální vizualizaci optického disku. Tato práce je součásti DAAD spolupráce mezi Ústavem Biomedicínského Inženýrství, Vysokého Učení Technického v Brně, Oční klinikou v Erlangenu a Ústavem Informačních Technologií, Friedrich-Alexander University, Erlangen-Nurnberg.This master thesis describes a conception of standard and advanced eye examination methods used for glaucoma diagnosis in its early stage. According to the theoretical knowledge, a web based information system for ophthalmologists with three main aims is implemented. The first aim is the possibility to share medical data of a concrete patient without sending his personal data through the Internet. The second aim is to create a patient account based on a complete eye examination procedure. The last aim is to improve the HRT diagnostic method with an image registration algorithm for the fundus and intensity images and create an optic nerve head web based 3D visualization. This master thesis is a part of project based on DAAD co-operation between Department of Biomedical Engineering, Brno University of Technology, Eye Clinic in Erlangen and Department of Computer Science, Friedrich-Alexander University, Erlangen-Nurnberg.

Human Retina Based Identification System Using Gabor Filters and GDA Technique

A biometric authentication system provides an automatic person authentication based on some characteristic features possessed by the individual. Among all other biometrics, human retina is a secure and reliable source of person recognition as it is unique, universal, lies at the back of the eyeball and hence it is unforgeable. The process of authentication mainly includes pre-processing, feature extraction and then features matching and classification. Also authentication systems are mainly appointed in verification and identification mode according to the specific application. In this paper, preprocessing and image enhancement stages involve several steps to highlight interesting features in retinal images. The feature extraction stage is accomplished using a bank of Gabor filter with number of orientations and scales. Generalized Discriminant Analysis (GDA) technique has been used to reduce the size of feature vectors and enhance the performance of proposed algorithm. Finally, classification is accomplished using k-nearest neighbor (KNN) classifier to determine the identity of the genuine user or reject the forged one as the proposed method operates in identification mode. The main contribution in this paper is using Generalized Discriminant Analysis (GDA) technique to address ‘curse of dimensionality’ problem. GDA is a novel method used in the area of retina recognition

Privacy in Biometric Systems

Biometrics are physiological and/or behavioral characteristics of a person that have been used to provide an automatic proof of identity in a growing list of applications including crime/terrorism fighting, forensics, access and border control, securing e-/m-commerce transactions and service entitlements. In recent years, a great deal of research into a variety of new and traditional biometrics has widened the scope of investigations beyond improving accuracy into mechanisms that deal with serious concerns raised about the potential misuse of collected biometric data. Despite the long list of biometrics’ benefits, privacy concerns have become widely shared due to the fact that every time the biometric of a person is checked, a trace is left that could reveal personal and confidential information. In fact, biometric-based recognition has an inherent privacy problem as it relies on capturing, analyzing, and storing personal data about us as individuals. For example, biometric systems deal with data related to the way we look (face, iris), the way we walk (gait), the way we talk (speaker recognition), the way we write (handwriting), the way we type on a keyboard (keystroke), the way we read (eye movement), and many more. Privacy has become a serious concern for the public as biometric systems are increasingly deployed in many applications ranging from accessing our account on a Smartphone or computer to border control and national biometric cards on a very large scale. For example, the Unique Identification Authority of India (UIDAI) has issued 56 million biometric cards as of January 2014 [1], where each biometric card holds templates of the 10 fingers, the two irises and the face. An essential factor behind the growing popularity of biometrics in recent years is the fact that biometric sensors have become a lot cheaper as well as easier to install and handle. CCTV cameras are installed nearly everywhere and almost all Smartphones are equipped with a camera, microphone, fingerprint scanner, and probably very soon, an iris scanner

A Review: Person Identification using Retinal Fundus Images

In this paper a review on biometric person identification has been discussed using features from retinal fundus image. Retina recognition is claimed to be the best person identification method among the biometric recognition systems as the retina is practically impossible to forge. It is found to be most stable, reliable and most secure among all other biometric systems. Retina inherits the property of uniqueness and stability. The features used in the recognition process are either blood vessel features or non-blood vessel features. But the vascular pattern is the most prominent feature utilized by most of the researchers for retina based person identification. Processes involved in this authentication system include pre-processing, feature extraction and feature matching. Bifurcation and crossover points are widely used features among the blood vessel features. Non-blood vessel features include luminance, contrast, and corner points etc. This paper summarizes and compares the different retina based authentication system. Researchers have used publicly available databases such as DRIVE, STARE, VARIA, RIDB, ARIA, AFIO, DRIDB, and SiMES for testing their methods. Various quantitative measures such as accuracy, recognition rate, false rejection rate, false acceptance rate, and equal error rate are used to evaluate the performance of different algorithms. DRIVE database provides 100\% recognition for most of the methods. Rest of the database the accuracy of recognition is more than 90\%