3,948,364 research outputs found

    Numerical Investigations on the Effect of Blade Angles of a Vertical Axis Wind Turbine on its Performance Output

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    There are many social, political and environmental issues associated with the use of fossil fuels. For this reason, there are numerous investigations currently being carried out to develop newer and renewable sources of energy to alleviate energy demand. Wind is one source of energy that can be harnessed using wind turbines. In this study, numerical investigations using Computational Fluid Dynamics (CFD) solver have been carried out to determine the optimum blade angles of a wind turbine used in urban environment. The effect of these blade angles have been considered to be within the normal operating range (α from 1.689⁰ to 21.689⁰, ϒ from 18.2⁰ to 38.2⁰ and ÎŽ from 22.357⁰ to 42.357⁰) while ÎČ was kept constant at 90⁰ due to design requirements. The results show that as α increases average torque output increases to a certain point after which it remains constant. On the contrary, as ϒ and ÎŽ increase, average torque output decreases. From the results, it can be concluded that the ideal blade angles, for optimal torque output, are α=11.689⁰, ϒ=18.2⁰ and ÎŽ=22.357⁰

    Front Park\u27s Past and Future

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    Front Park is a 26-acre urban park in Buffalo, New York. The park entrance is located on Porter Avenue. The park is bounded on the west by interstate 190, on the north by the Peace Bridge truck plaza and on the north by Busti Avenue and the adjacent Columbus Park-Prospect Hill neighborhood. Front Park is part of Buffalo’s Olmsted park system. The park system takes its name from its most prominent original designer, Frederick Law Olmsted Sr., a nationally renowned landscape architect who along with his partner, Calvert Vaux, designed parks and park systems across the country, including New York City’s Central Park. Olmsted’s work in New York City garnered the attention of prominent Buffalonians, who hired him to design a park system in 1868. Buffalo’s Olmsted park system was designed over a nearly 50-year period, from 1869 to 1915

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    Edith Macpherson Park: Testament to a Pioneering Biodynamic Farmer

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    A public park is a fitting testament to a pioneer biodynamic and organic farmer. Edith Macpherson Park is a public park, located in Namur Street, Noble Park, a south-east suburb of Melbourne, Victoria, Australia). Edith Macpherson Park offers visitors a quiet, green, grassy, leafy refuge in suburban Melbourne. The park has a nicely appointed and maintained children’s playground, as well as a public barbeque. Edith Ileen Macpherson (1898-1984) bequeathed the park land to the Dandenong City Council. In life, she was always known as ‘Ileen’, her middle name. Her modest weatherboard house had been purpose-designed and built to accommodate her own special needs. This disability-access house served her for three decades, but in her will she specified that it be razed to the ground leaving no trace - and so it was. The playground of Edith Macpherson Park occupies the site of the demolished house. Ileen Macpherson and Ernesto Genoni’s Demeter Farm operated for two decades (1934-1954). Ernesto and Ileen were both members of the Rudolf Steiner’s Experimental Circle of Anthroposophic Farmers and Gardeners which was headquartered in Dornach, Switzerland. An imperative is to correct the name of the park from ‘Edith Macpherson Park’ to ‘Ileen Macpherson Park’. The Park ought to bear the name which the donor bore all of her life - rather than a name by which she was never known, albeit that ‘Edith Ileen Macpherson’ appears on her birth certificate, death certificate, and her will. This simple name rectification would properly honour the life and generosity of the donor who pioneered of biodynamic and organic farming in Australia

    The impacts of tourism on two communities adjacent to the Kruger National Park, South Africa

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    This paper explores the socioeconomic impacts of tourism associated with the Kruger National Park, South Africa's flagship national park, on the neighbouring villages of Cork and Belfast. Case study research, where the study area was characterised as a social-ecological system, was used to investigate the impacts of Park tourism on these communities. The findings offer a micro-scale, local community perspective of these impacts and indicate that the enclave nature of Park tourism keeps local communities separate from the Park and makes it hard for them to benefit from it. The paper concludes with reflections on this perceived separation, and suggests the need to make the Park boundaries more 'permeable' so as to improve relationships with adjacent communities, while also pragmatically managing community expectation

    Excerpts from the Novel, Bear War-den

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    A woman park warden who works in Rocky Mountain National Park spends her time on such tasks as bear patrol, locating tourists who are lost or in other physical danger, and policing park rules. She has a particular affinity for grizzly bears, largely stemming from an experience she had in a Neolithic cave in Spain. During her work and her travels, she observes various ways in which bears are mistreated in parks, sometimes even by researchers with seemingly good intentions. While an out-of-control fire rages through the national park, the woman park warden, with two grizzly bear skulls in hand, begins a difficult and dream-like journey to the park boundary—where wild animals can seem like ghosts and trauma can strike as suddenly as lightning

    Counting conjugacy classes of cyclic subgroups for fusion systems

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    We give another proof of an observation of Th\'evenaz \cite{T1989} and present a fusion system version of it. Namely, for a saturated fusion system \CF on a finite pp-group SS, we show that the number of the \CF-conjugacy classes of cyclic subgroups of SS is equal to the rank of certain square matrices of numbers of orbits, coming from characteristic bisets, the characteristic idempotent and finite groups realizing the fusion system \CF as in our previous work \cite{P2010}.Comment: 5 page

    Data-driven multivariate and multiscale methods for brain computer interface

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    This thesis focuses on the development of data-driven multivariate and multiscale methods for brain computer interface (BCI) systems. The electroencephalogram (EEG), the most convenient means to measure neurophysiological activity due to its noninvasive nature, is mainly considered. The nonlinearity and nonstationarity inherent in EEG and its multichannel recording nature require a new set of data-driven multivariate techniques to estimate more accurately features for enhanced BCI operation. Also, a long term goal is to enable an alternative EEG recording strategy for achieving long-term and portable monitoring. Empirical mode decomposition (EMD) and local mean decomposition (LMD), fully data-driven adaptive tools, are considered to decompose the nonlinear and nonstationary EEG signal into a set of components which are highly localised in time and frequency. It is shown that the complex and multivariate extensions of EMD, which can exploit common oscillatory modes within multivariate (multichannel) data, can be used to accurately estimate and compare the amplitude and phase information among multiple sources, a key for the feature extraction of BCI system. A complex extension of local mean decomposition is also introduced and its operation is illustrated on two channel neuronal spike streams. Common spatial pattern (CSP), a standard feature extraction technique for BCI application, is also extended to complex domain using the augmented complex statistics. Depending on the circularity/noncircularity of a complex signal, one of the complex CSP algorithms can be chosen to produce the best classification performance between two different EEG classes. Using these complex and multivariate algorithms, two cognitive brain studies are investigated for more natural and intuitive design of advanced BCI systems. Firstly, a Yarbus-style auditory selective attention experiment is introduced to measure the user attention to a sound source among a mixture of sound stimuli, which is aimed at improving the usefulness of hearing instruments such as hearing aid. Secondly, emotion experiments elicited by taste and taste recall are examined to determine the pleasure and displeasure of a food for the implementation of affective computing. The separation between two emotional responses is examined using real and complex-valued common spatial pattern methods. Finally, we introduce a novel approach to brain monitoring based on EEG recordings from within the ear canal, embedded on a custom made hearing aid earplug. The new platform promises the possibility of both short- and long-term continuous use for standard brain monitoring and interfacing applications

    Decitabine, a DNA-demethylating agent, promotes differentiation via NOTCH1 signaling and alters immune-related pathways in muscle-invasive bladder cancer

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    Aberrant DNA methylation observed in cancer can provide survival benefits to cells by silencing genes essential for anti-tumor activity. DNA-demethylating agents such as Decitabine (DAC)/Azacitidine (AZA) activate otherwise silenced tumor suppressor genes, alter immune response and epigenetically reprogram tumor cells. In this study, we show that non-cytotoxic nanomolar DAC concentrations modify the bladder cancer transcriptome to activate NOTCH1 at the mRNA and protein level, increase double-stranded RNA sensors and CK5-dependent differentiation. Importantly, DAC treatment increases ICN1 expression (the active intracellular domain of NOTCH1) significantly inhibiting cell proliferation and causing changes in cell size inducing morphological alterations reminiscent of senescence. These changes were not associated with ÎČ-galactosidase activity or increased p16 levels, but instead were associated with substantial IL-6 release. Increased IL-6 release was observed in both DAC-treated and ICN1 overexpressing cells as compared to control cells. Exogenous IL-6 expression was associated with a similar enlarged cell morphology that was rescued by the addition of a monoclonal antibody against IL-6. Treatment with DAC, overexpression with ICN1 or addition of exogenous IL-6 showed CK5 reduction, a surrogate marker of differentiation. Overall this study suggests that in MIBC cells, DNA hypomethylation increases NOTCH1 expression and IL-6 release to induce CK5-related differentiation.Fil: Ramakrishnan, Swathi. Roswell Park Cancer Institute; Estados UnidosFil: Hu, Qiang. Roswell Park Cancer Institute; Estados UnidosFil: Krishnan, Nithya. Roswell Park Cancer Institute; Estados UnidosFil: Wang, Dan. Roswell Park Cancer Institute; Estados UnidosFil: Smit, Evelyn. Roswell Park Cancer Institute; Estados UnidosFil: Granger, Victoria. Roswell Park Cancer Institute; Estados UnidosFil: Rak, Monika. Jagiellonian University; PoloniaFil: Attwood, Kristopher. Roswell Park Cancer Institute; Estados UnidosFil: Johnson, Candace. Roswell Park Cancer Institute; Estados UnidosFil: Morrison, Carl. Roswell Park Cancer Institute; Estados UnidosFil: Pili, Roberto. Indiana University; Estados UnidosFil: Chatta, Gurkamal. Roswell Park Cancer Institute; Estados UnidosFil: Guru, Khurshid. Roswell Park Cancer Institute; Estados UnidosFil: Gueron, Geraldine. Consejo Nacional de Investigaciones CientĂ­ficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Ciudad Universitaria. Instituto de QuĂ­mica BiolĂłgica de la Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de QuĂ­mica BiolĂłgica de la Facultad de Ciencias Exactas y Naturales; ArgentinaFil: McNally, Lacey. University of Louisville; Estados UnidosFil: Wang, Jianmin. Roswell Park Cancer Institute; Estados UnidosFil: Woloszynska-Read, Anna. Roswell Park Cancer Institute; Estados Unido
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