Is God’s Benevolence Impartial?

In this paper I consider the intuitive idea that God is fair and does not play favorites. This belief appears to be held by many theists. I will call it the Principle of Impartial Benevolence (PIB) and put it as follows: As much as possible, for all persons, God equally promotes the good and equally prevents the bad. I begin with the conviction that there is a prima facie tension between PIB and the disparity of human suffering. My aim in what follows is to clarify this tension and show that it runs deep. More specifically, I will argue that PIB imposes stringent demands—including a patient-centered theodicy—on the sorts of reasons that would justify God in permitting suffering, and, that the historical disparity of suffering indicates that these demands are not met. I conclude that theists should disavow PIB or at least consider it sub judice

Telechelic polyisobutylene with unsaturated end groups and with anhydride end groups

Anhydride terminated polyisobutylene (PIB) oligomers were synthesized in a one- or two-step process from chlorine terminated oligomers. In the one-step process, chlorine functional oligomers were just heated in the presence of maleic anhydride (MA) for 12 h at 190°C without a catalyst. In the two-step process, the chlorine end functional groups were first converted by selective dehydrochlorination to isopropenylpoly-isobutylene end groups with t-BuOK in refluxing tetrahydrofuran during 16 h. In a second step, MA was coupled to the PIB with unsaturated end groups by reacting the oligomer with MA for 12 h at 190°C. These reactions could be followed by i.r. and n.m.r. The PIB-MA obtained had a functionality between 30% and 100%. In order to study the formation of amine functionalities, the PIB-MA was reacted with diamines. The coupling gave an imide bonding

Illustrating Electric Conductivity Using the Particle-in-a-Box Model: Quantum Superposition is the Key

Most of the textbooks explaining electric conductivity in the context of quantum mechanics provide either incomplete or semi-classical explanations that are not connected with the elementary concepts of quantum mechanics. We illustrate the conduction phenomena using the simplest model system in quantum dynamics, a particle in a box (PIB). To induce the particle dynamics, a linear potential tilting the bottom of the box is introduced, which is equivalent to imposing a constant electric field for a charged particle. Although the PIB model represents a closed system that cannot have a flow of electrons through the system, we consider the oscillatory dynamics of the particle probability density as the analogue of the electric current. Relating the amplitude and other parameters of the particle oscillatory dynamics with the gap between the ground and excited states of the PIB model allows us to demonstrate one of the most basic dependencies of electric conductivity on the valence-conduction band gap of the material

Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo.

Amyloid imaging represents a major advance in neuroscience, enabling the detection and quantification of pathologic protein aggregations in the brain. In this review we survey current amyloid imaging techniques, focusing on positron emission tomography (PET) with (11)carbon-labelled Pittsburgh Compound-B ((11)C-PIB), the most extensively studied and best validated tracer. PIB binds specifically to fibrillar beta-amyloid (Abeta) deposits, and is a sensitive marker for Abeta pathology in cognitively normal older individuals and patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD). PIB-PET provides us with a powerful tool to examine in vivo the relationship between amyloid deposition, clinical symptoms, and structural and functional brain changes in the continuum between normal aging and AD. Amyloid imaging studies support a model in which amyloid deposition is an early event on the path to dementia, beginning insidiously in cognitively normal individuals, and accompanied by subtle cognitive decline and functional and structural brain changes suggestive of incipient AD. As patients progress to dementia, clinical decline and neurodegeneration accelerate and proceed independently of amyloid accumulation. In the future, amyloid imaging is likely to supplement clinical evaluation in selecting patients for anti-amyloid therapies, while MRI and FDG-PET may be more appropriate markers of clinical progression

Investimento estrangeiro direto e crescimento econômico na Jordânia: uma pesquisa empírica que utiliza o teste de limites de cointegração

Este artículo investiga las elasticidades a largo y corto plazo entre el producto interno bruto y la IED en Jordania. El estudio utiliza datos anuales para analizar la relación entre la IED y el crecimiento económico para el periodo de 1992-2013. Los datos para las variables IED y PIB se obtuvieron de los Indicadores del Desarrollo Mundial y del Banco Mundial, y se utilizó el enfoque ARDL. Los resultados muestran elasticidades de largo y corto plazo en la IED y el PIB. En general, los responsables políticos de Jordania centran sus esfuerzos para atraer más IED a la economía jordana. Esto se debe a que se espera que más IED en la economía jordana conduzca a una disminución de los obstáculos económicos (por ejemplo, disminución de la tasa de desempleo y mayor nivel de inversión).Este artigo pesquisa sobre as elasticidades em curto e longo prazo entre o produto interno bruto (PIB) e o investimento estrangeiro direto (IED) na Jordânia. Este estudo utiliza dados anuais para analisar a relação entre a IED e o crescimento econômico para o período de 1992-2013. Os dados para as variáveis IED e PIB foram obtidos dos Indicadores do Desenvolvimento Mundial e do Banco Mundial, e foi utilizada a abordagem Autorregressiva com Defasagens Distribuídas (ARDL). Os resultados indicam elasticidades de curto e longo prazo no IED e no PIB. Em geral, os responsáveis políticos da Jordânia focam seus esforços para atrair mais IED à economia jordana. Isso se deve a que se espera que mais IED na economia jordana leve a uma diminuição dos obstáculos econômicos (por exemplo, diminuição da taxa de desemprego, maior nível de investimento).This paper investigates both long-run and short-run elasticities between gross domestic product and foreign direct investment (FDI) in Jordan. Annual data have been used in order to explore the relationship between foreign direct investments (FDI) with economic growth for the period 1992-2013. Data were collected for both variables (FDI and GDP) from the World Bank and World Development Indicators, and the Autoregressive Distributed Lag Model (ARDL) approach was used. The results show long-run and short-run elasticities in foreign direct investment (FDI) and GDP. The results indicate that Jordanian policy makers focus their efforts to attract more FDI to Jordanian economy. This is because more FDI is expected to lead to a decrease in economic obstacles in Jordan (e.g., increased level of investment, decreased unemployment rate)

Bioassay of the Nucleopolyhedrosis Virus of \u3ci\u3eNeodiprion Sertifer\u3c/i\u3e (Hymenoptera: Diprionidae)

Linear regression analysis of probit mortality versus several concentrations of nucleo- polyhedrosis virus of Neodiprion sertifer resulted in the equation Y = 2.170 + 0.872X. An LC50 was calculated at 1758 PIB/mL Also, the incubation time of the virus was dependent on Its concentration

Local and distributed PiB accumulation associated with development of preclinical Alzheimer\u27s disease

Amyloid-beta plaques are a hallmark of Alzheimer\u27s disease (AD) that can be assessed by amyloid imaging (e.g., Pittsburgh B compound [PiB]) and summarized as a scalar value. Summary values may have clinical utility but are an average over many regions of interest, potentially obscuring important topography. This study investigates the longitudinal evolution of amyloid topographies in cognitively normal older adults who had normal (N = 131) or abnormal (N = 26) PiB scans at baseline. At 3 years follow-up, 16 participants with a previously normal PiB scan had conversion to PiB scans consistent with preclinical AD. We investigated the multivariate relationship (canonical correlation) between baseline and follow-up PiB topographies. Furthermore, we used penalized regression to investigate the added information derived from PiB topography compared to summary measures. PiB accumulation can be local, that is, a topography predicting the same topography in the future, and/or distributed, that is, one topography predicting another. Both local and distributed PiB accumulation was associated with conversion of PiB status. Additionally, elements of the multivariate topography, and not the commonly used summary scalar, correlated with future PiB changes. Consideration of the entire multivariate PiB topography provides additional information regarding the development of amyloid-beta pathology in very early preclinical AD