178 research outputs found

    Global solutions for a hyperbolic-parabolic system of chemotaxis

    Full text link
    We study a hyperbolic-parabolic model of chemotaxis in dimensions one and two. In particular, we prove the global existence of classical solutions in certain dissipation regimes

    Mathematical description of bacterial traveling pulses

    Get PDF
    The Keller-Segel system has been widely proposed as a model for bacterial waves driven by chemotactic processes. Current experiments on {\em E. coli} have shown precise structure of traveling pulses. We present here an alternative mathematical description of traveling pulses at a macroscopic scale. This modeling task is complemented with numerical simulations in accordance with the experimental observations. Our model is derived from an accurate kinetic description of the mesoscopic run-and-tumble process performed by bacteria. This model can account for recent experimental observations with {\em E. coli}. Qualitative agreements include the asymmetry of the pulse and transition in the collective behaviour (clustered motion versus dispersion). In addition we can capture quantitatively the main characteristics of the pulse such as the speed and the relative size of tails. This work opens several experimental and theoretical perspectives. Coefficients at the macroscopic level are derived from considerations at the cellular scale. For instance the stiffness of the signal integration process turns out to have a strong effect on collective motion. Furthermore the bottom-up scaling allows to perform preliminary mathematical analysis and write efficient numerical schemes. This model is intended as a predictive tool for the investigation of bacterial collective motion

    On the fractional Fisher information with applications to a hyperbolic-parabolic system of chemotaxis

    Get PDF
    We introduce new lower bounds for the fractional Fisher information. Equipped with these bounds we study a hyperbolic-parabolic model of chemotaxis and prove the global existence of solutions in certain dissipation regimes

    Boundedness and homogeneous asymptotics for a fractional logistic Keller-Segel equations

    Full text link
    In this paper we consider a dd-dimensional (d=1,2d=1,2) parabolic-elliptic Keller-Segel equation with a logistic forcing and a fractional diffusion of order α∈(0,2)\alpha \in (0,2). We prove uniform in time boundedness of its solution in the supercritical range α>d(1−c)\alpha>d\left(1-c\right), where cc is an explicit constant depending on parameters of our problem. Furthermore, we establish sufficient conditions for ∥u(t)−u∞∥L∞→0\|u(t)-u_\infty\|_{L^\infty}\rightarrow0, where u∞≡1u_\infty\equiv 1 is the only nontrivial homogeneous solution. Finally, we provide a uniqueness result

    Travelling waves in hyperbolic chemotaxis equations

    Get PDF
    Mathematical models of bacterial populations are often written as systems of partial differential equations for the densities of bacteria and concentrations of extracellular (signal) chemicals. This approach has been employed since the seminal work of Keller and Segel in the 1970s [Keller and Segel, J. Theor. Biol., 1971]. The system has been shown to permit travelling wave solutions which correspond to travelling band formation in bacterial colonies, yet only under specific criteria, such as a singularity in the chemotactic sensitivity function as the signal approaches zero. Such a singularity generates infinite macroscopic velocities which are biologically unrealistic. In this paper, we formulate a model that takes into consideration relevant details of the intracellular processes while avoiding the singularity in the chemotactic sensitivity. We prove the global existence of solutions and then show the existence of travelling wave solutions both numerically and analytically
    • …
    corecore