The drug logistics process: an innovation experience

Purpose - The purpose of this paper is to present the latest innovations in the drug distribution processes of hospital companies, which are currently dealing with high inventory and storage costs and fragmented organizational responsibilities. Design/methodology/approach - The literature review and the in-depth analysis of a case study support the understanding of the unit dose drug distribution system and the subsequent definition of the practical implications for hospital companies. Findings - Starting from the insights offered by the case study, the analysis shows that the unit dose system allows hospitals to improve the patient care quality and reduce costs. Research limitations/implications - The limitations of the research are those related to the theoretical and exploratory nature of the study, but from a practical point of view, the work provides important indications to the management of healthcare companies, which have to innovate their drug distribution systems. Originality/value - This paper analyzes a new and highly topical issue and provides several insights for the competitive development of a fundamental sector

The End of a Myth: Distributed Transactions Can Scale

The common wisdom is that distributed transactions do not scale. But what if distributed transactions could be made scalable using the next generation of networks and a redesign of distributed databases? There would be no need for developers anymore to worry about co-partitioning schemes to achieve decent performance. Application development would become easier as data placement would no longer determine how scalable an application is. Hardware provisioning would be simplified as the system administrator can expect a linear scale-out when adding more machines rather than some complex sub-linear function, which is highly application specific. In this paper, we present the design of our novel scalable database system NAM-DB and show that distributed transactions with the very common Snapshot Isolation guarantee can indeed scale using the next generation of RDMA-enabled network technology without any inherent bottlenecks. Our experiments with the TPC-C benchmark show that our system scales linearly to over 6.5 million new-order (14.5 million total) distributed transactions per second on 56 machines.Comment: 12 page

GPUs as Storage System Accelerators

Massively multicore processors, such as Graphics Processing Units (GPUs), provide, at a comparable price, a one order of magnitude higher peak performance than traditional CPUs. This drop in the cost of computation, as any order-of-magnitude drop in the cost per unit of performance for a class of system components, triggers the opportunity to redesign systems and to explore new ways to engineer them to recalibrate the cost-to-performance relation. This project explores the feasibility of harnessing GPUs' computational power to improve the performance, reliability, or security of distributed storage systems. In this context, we present the design of a storage system prototype that uses GPU offloading to accelerate a number of computationally intensive primitives based on hashing, and introduce techniques to efficiently leverage the processing power of GPUs. We evaluate the performance of this prototype under two configurations: as a content addressable storage system that facilitates online similarity detection between successive versions of the same file and as a traditional system that uses hashing to preserve data integrity. Further, we evaluate the impact of offloading to the GPU on competing applications' performance. Our results show that this technique can bring tangible performance gains without negatively impacting the performance of concurrently running applications.Comment: IEEE Transactions on Parallel and Distributed Systems, 201

Kernel arquitecture for CAD/CAM in shipbuilding enviroments

The capabilities of complex software products such as CAD/CAM systems are strongly supported by basic information technologies related with data management, visualization, communication, geometry modeling and others related with the development process. These basic information technologies are involved in a continuous evolution process, but over recent years this evolution has been dramatic. The main reason for this has been that new hardware capabilities (including graphic cards) are available at very low cost, but also a contributing factor has been the evolution of the prices of basic software. To take advantage of these new features, the existing CAD/CAM systems must undergo a complete and drastic redesign. This process is complicated but strategic for the future evolution of a system. There are several examples in the market of how a bad decision has lead to a cul-de-sac (both technically and commercially). This paper describes what the authors consider are the basic architectural components of a kernel for a CAD/CAM system oriented to shipbuilding. The proposed solution is a combination of in-house developed frameworks together with commercial products that are accepted as standard components. The proportion of in-house frameworks within this combination of products is a key factor, especially when considering CAD/CAM systems oriented to shipbuilding. General-purpose CAD/CAM systems are mainly oriented to the mechanical CAD market. For this reason several basic products exist devoted to geometry modelling in this context. But these basic products are not well suited to deal with the very specific geometry modelling requirements of a CAD/CAM system oriented to shipbuilding. The complexity of the ship model, the different model requirements through its short and changing life cycle and the many different disciplines involved in the process are reasons for this inadequacy. Apart from these basic frameworks, specific shipbuilding frameworks are also required. This second layer is built over the basic technology components mentioned above. This paper describes in detail the technological frameworks which have been used to develop the latest FORAN version.Postprint (published version

The knowledge domain of chain and network science

This editorial paper aims to provide a framework to categorise and evaluate the domain of Chain and Network Science (CNS), and to provide an envelope for the research and management agenda. The authors strongly feel that although considerable progress has been made over the past couple of years in the development of the CNS domain, a number of important and exciting challenges are still waiting to be tackled. This paper provides a definition of the object of study of CNS, its central problem area, the organisation and governance of chain and network co-operation, and the relationships between chain organisation and technology development, market dynamics, and the economy and society at large. It indicates relevant sources of knowledge among the various academic disciplines. It touches upon CNS problem solving by identifying areas for knowledge development and CNS tool construction

MODELS AND SOLUTIONS FOR THE IMPLEMENTATION OF DISTRIBUTED SYSTEMS

Software applications may have different degrees of complexity depending on the problems they try to solve and can integrate very complex elements that bring together functionality that sometimes are competing or conflicting. We can take for example a mobile communications system. Functionalities of such a system are difficult to understand, and they add to the non-functional requirements such as the use in practice, performance, cost, durability and security. The transition from local computer networks to cover large networks that allow millions of machines around the world at speeds exceeding one gigabit per second allowed universal access to data and design of applications that require simultaneous use of computing power of several interconnected systems. The result of these technologies has enabled the evolution from centralized to distributed systems that connect a large number of computers. To enable the exploitation of the advantages of distributed systems one had developed software and communications tools that have enabled the implementation of distributed processing of complex solutions. The objective of this document is to present all the hardware, software and communication tools, closely related to the possibility of their application in integrated social and economic level as a result of globalization and the evolution of e-society. These objectives and national priorities are based on current needs and realities of Romanian society, while being consistent with the requirements of Romania's European orientation towards the knowledge society, strengthening the information society, the target goal representing the accomplishment of e-Romania, with its strategic e-government component. Achieving this objective repositions Romania and gives an advantage for sustainable growth, positive international image, rapid convergence in Europe, inclusion and strengthening areas of high competence, in line with Europe 2020, launched by the European Council in June 2010.information society, databases, distributed systems, e-society, implementation of distributed systems

A Configurable Transport Layer for CAF

The message-driven nature of actors lays a foundation for developing scalable and distributed software. While the actor itself has been thoroughly modeled, the message passing layer lacks a common definition. Properties and guarantees of message exchange often shift with implementations and contexts. This adds complexity to the development process, limits portability, and removes transparency from distributed actor systems. In this work, we examine actor communication, focusing on the implementation and runtime costs of reliable and ordered delivery. Both guarantees are often based on TCP for remote messaging, which mixes network transport with the semantics of messaging. However, the choice of transport may follow different constraints and is often governed by deployment. As a first step towards re-architecting actor-to-actor communication, we decouple the messaging guarantees from the transport protocol. We validate our approach by redesigning the network stack of the C++ Actor Framework (CAF) so that it allows to combine an arbitrary transport protocol with additional functions for remote messaging. An evaluation quantifies the cost of composability and the impact of individual layers on the entire stack

DIDET: Digital libraries for distributed, innovative design education and teamwork. Final project report

The central goal of the DIDET Project was to enhance student learning opportunities by enabling them to partake in global, team based design engineering projects, in which they directly experience different cultural contexts and access a variety of digital information sources via a range of appropriate technology. To achieve this overall project goal, the project delivered on the following objectives: 1. Teach engineering information retrieval, manipulation, and archiving skills to students studying on engineering degree programs. 2. Measure the use of those skills in design projects in all years of an undergraduate degree program. 3. Measure the learning performance in engineering design courses affected by the provision of access to information that would have been otherwise difficult to access. 4. Measure student learning performance in different cultural contexts that influence the use of alternative sources of information and varying forms of Information and Communications Technology. 5. Develop and provide workshops for staff development. 6. Use the measurement results to annually redesign course content and the digital libraries technology. The overall DIDET Project approach was to develop, implement, use and evaluate a testbed to improve the teaching and learning of students partaking in global team based design projects. The use of digital libraries and virtual design studios was used to fundamentally change the way design engineering is taught at the collaborating institutions. This was done by implementing a digital library at the partner institutions to improve learning in the field of Design Engineering and by developing a Global Team Design Project run as part of assessed classes at Strathclyde, Stanford and Olin. Evaluation was carried out on an ongoing basis and fed back into project development, both on the class teaching model and the LauLima system developed at Strathclyde to support teaching and learning. Major findings include the requirement to overcome technological, pedagogical and cultural issues for successful elearning implementations. A need for strong leadership has been identified, particularly to exploit the benefits of cross-discipline team working. One major project output still being developed is a DIDET Project Framework for Distributed Innovative Design, Education and Teamwork to encapsulate all project findings and outputs. The project achieved its goal of embedding major change to the teaching of Design Engineering and Strathclyde's new Global Design class has been both successful and popular with students