Medical data processing and analysis for remote health and activities monitoring

Recent developments in sensor technology, wearable computing, Internet of Things (IoT), and wireless communication have given rise to research in ubiquitous healthcare and remote monitoring of human\u2019s health and activities. Health monitoring systems involve processing and analysis of data retrieved from smartphones, smart watches, smart bracelets, as well as various sensors and wearable devices. Such systems enable continuous monitoring of patients psychological and health conditions by sensing and transmitting measurements such as heart rate, electrocardiogram, body temperature, respiratory rate, chest sounds, or blood pressure. Pervasive healthcare, as a relevant application domain in this context, aims at revolutionizing the delivery of medical services through a medical assistive environment and facilitates the independent living of patients. In this chapter, we discuss (1) data collection, fusion, ownership and privacy issues; (2) models, technologies and solutions for medical data processing and analysis; (3) big medical data analytics for remote health monitoring; (4) research challenges and opportunities in medical data analytics; (5) examples of case studies and practical solutions

Unsupervised monitoring of an elderly person\u27s activities of daily living using Kinect sensors and a power meter

The need for greater independence amongst the growing population of elderly people has made the concept of “ageing in place” an important area of research. Remote home monitoring strategies help the elderly deal with challenges involved in ageing in place and performing the activities of daily living (ADLs) independently. These monitoring approaches typically involve the use of several sensors, attached to the environment or person, in order to acquire data about the ADLs of the occupant being monitored. Some key drawbacks associated with many of the ADL monitoring approaches proposed for the elderly living alone need to be addressed. These include the need to label a training dataset of activities, use wearable devices or equip the house with many sensors. These approaches are also unable to concurrently monitor physical ADLs to detect emergency situations, such as falls, and instrumental ADLs to detect deviations from the daily routine. These are all indicative of deteriorating health in the elderly. To address these drawbacks, this research aimed to investigate the feasibility of unsupervised monitoring of both physical and instrumental ADLs of elderly people living alone via inexpensive minimally intrusive sensors. A hybrid framework was presented which combined two approaches for monitoring an elderly occupant’s physical and instrumental ADLs. Both approaches were trained based on unlabelled sensor data from the occupant’s normal behaviours. The data related to physical ADLs were captured from Kinect sensors and those related to instrumental ADLs were obtained using a combination of Kinect sensors and a power meter. Kinect sensors were employed in functional areas of the monitored environment to capture the occupant’s locations and 3D structures of their physical activities. The power meter measured the power consumption of home electrical appliances (HEAs) from the electricity panel. A novel unsupervised fuzzy approach was presented to monitor physical ADLs based on depth maps obtained from Kinect sensors. Epochs of activities associated with each monitored location were automatically identified, and the occupant’s behaviour patterns during each epoch were represented through the combinations of fuzzy attributes. A novel membership function generation technique was presented to elicit membership functions for attributes by analysing the data distribution of attributes while excluding noise and outliers in the data. The occupant’s behaviour patterns during each epoch of activity were then classified into frequent and infrequent categories using a data mining technique. Fuzzy rules were learned to model frequent behaviour patterns. An alarm was raised when the occupant’s behaviour in new data was recognised as frequent with a longer than usual duration or infrequent with a duration exceeding a data-driven value. Another novel unsupervised fuzzy approach to monitor instrumental ADLs took unlabelled training data from Kinect sensors and a power meter to model the key features of instrumental ADLs. Instrumental ADLs in the training dataset were identified based on associating the occupant’s locations with specific power signatures on the power line. A set of fuzzy rules was then developed to model the frequency and regularity of the instrumental activities tailored to the occupant. This set was subsequently used to monitor new data and to generate reports on deviations from normal behaviour patterns. As a proof of concept, the proposed monitoring approaches were evaluated using a dataset collected from a real-life setting. An evaluation of the results verified the high accuracy of the proposed technique to identify the epochs of activities over alternative techniques. The approach adopted for monitoring physical ADLs was found to improve elderly monitoring. It generated fuzzy rules that could represent the person’s physical ADLs and exclude noise and outliers in the data more efficiently than alternative approaches. The performance of different membership function generation techniques was compared. The fuzzy rule set obtained from the output of the proposed technique could accurately classify more scenarios of normal and abnormal behaviours. The approach for monitoring instrumental ADLs was also found to reliably distinguish power signatures generated automatically by self-regulated devices from those generated as a result of an elderly person’s instrumental ADLs. The evaluations also showed the effectiveness of the approach in correctly identifying elderly people’s interactions with specific HEAs and tracking simulated upward and downward deviations from normal behaviours. The fuzzy inference system in this approach was found to be robust in regards to errors when identifying instrumental ADLs as it could effectively classify normal and abnormal behaviour patterns despite errors in the list of the used HEAs

Machine learning methods for detecting urinary tract infection and analysing daily living activities in people with dementia

Dementia is a neurological and cognitive condition that affects millions of people around the world. At any given time in the United Kingdom, 1 in 4 hospital beds are occupied by a person with dementia, while about 22% of these hospital admissions are due to preventable causes. In this paper we discuss using Internet of Things (IoT) technologies and in-home sensory devices in combination with machine learning techniques to monitor health and well-being of people with dementia. This will allow us to provide more effective and preventative care and reduce preventable hospital admissions. One of the unique aspects of this work is combining environmental data with physiological data collected via low cost in-home sensory devices to extract actionable information regarding the health and well-being of people with dementia in their own home environment. We have worked with clinicians to design our machine learning algorithms where we focused on developing solutions for real-world settings. In our solutions, we avoid generating too many alerts/alarms to prevent increasing the monitoring and support workload. We have designed an algorithm to detect Urinary Tract Infections (UTI) which is one of the top five reasons of hospital admissions for people with dementia (around 9% of hospital admissions for people with dementia in the UK). To develop the UTI detection algorithm, we have used a Non-negative Matrix Factorisation (NMF) technique to extract latent factors from raw observation and use them for clustering and identifying the possible UTI cases. In addition, we have designed an algorithm for detecting changes in activity patterns to identify early symptoms of cognitive decline or health decline in order to provide personalised and preventative care services. For this purpose, we have used an Isolation Forest (iForest) technique to create a holistic view of the daily activity patterns. This paper describes the algorithms and discusses the evaluation of the work using a large set of real-world data collected from a trial with people with dementia and their caregivers

Earthquake Arrival Association with Backprojection and Graph Theory

The association of seismic wave arrivals with causative earthquakes becomes progressively more challenging as arrival detection methods become more sensitive, and particularly when earthquake rates are high. For instance, seismic waves arriving across a monitoring network from several sources may overlap in time, false arrivals may be detected, and some arrivals may be of unknown phase (e.g., P- or S-waves). We propose an automated method to associate arrivals with earthquake sources and obtain source locations applicable to such situations. To do so we use a pattern detection metric based on the principle of backprojection to reveal candidate sources, followed by graph-theory-based clustering and an integer linear optimization routine to associate arrivals with the minimum number of sources necessary to explain the data. This method solves for all sources and phase assignments simultaneously, rather than in a sequential greedy procedure as is common in other association routines. We demonstrate our method on both synthetic and real data from the Integrated Plate Boundary Observatory Chile (IPOC) seismic network of northern Chile. For the synthetic tests we report results for cases with varying complexity, including rates of 500 earthquakes/day and 500 false arrivals/station/day, for which we measure true positive detection accuracy of > 95%. For the real data we develop a new catalog between January 1, 2010 - December 31, 2017 containing 817,548 earthquakes, with detection rates on average 279 earthquakes/day, and a magnitude-of-completion of ~M1.8. A subset of detections are identified as sources related to quarry and industrial site activity, and we also detect thousands of foreshocks and aftershocks of the April 1, 2014 Mw 8.2 Iquique earthquake. During the highest rates of aftershock activity, > 600 earthquakes/day are detected in the vicinity of the Iquique earthquake rupture zone

Anomaly Detection from Low-dimensional Latent Manifolds with Home Environmental Sensors

Human Activity Recognition poses a significant challenge within Active and Assisted Living (AAL) systems, relying extensively on ubiquitous environmental sensor-based acquisition devices to detect user situations in their daily living. Environmental measurement systems deployed indoors yield multiparametric data in heterogeneous formats, which presents a challenge for developing Machine Learning-based AAL models. We hypothesized that anomaly detection algorithms could be effectively employed to create data-driven models for monitoring home environments and that the complex multiparametric indoor measurements can often be represented by a relatively small number of latent variables generated through Manifold Learning (MnL) techniques. We examined both linear (Principal Component Analysis) and non-linear (AutoEncoders) techniques for generating these latent spaces and the utility of core domain detection techniques for identifying anomalies within the resulting low-dimensional manifolds. We benchmarked this approach using three publicly available datasets (hh105, Aruba, and Tulum) and one proprietary dataset (Elioth) for home environmental monitoring. Our results demonstrated the following key findings: (a) Nonlinear manifold estimation techniques offer significant advantages in retrieving latent variables when compared to linear techniques; (b) The quality of the reconstruction of the original multidimensional recordings serves as an acceptable indicator of the quality of the generated latent spaces; (c) Domain detection identifies regions of normality consistent with typical individual activities in these spaces; And (d) the system effectively detects deviations from typical activity patterns and labels anomalies. This study lays the groundwork for further exploration of enhanced methods for extracting information from MnL data models and their application within the AAL and possibly other sectors