Localization and Spreading of Diseases in Complex Networks

Using the SIS model on unweighted and weighted networks, we consider the disease localizationphenomenon. In contrast to the well-recognized point of view that diseases infect a finite fractionof vertices right above the epidemic threshold, we show that diseases can be localized on a finitenumber of vertices, where hubs and edges with large weights are centers of localization. Our resultsfollow from the analysis of standard models of networks and empirical data for real-world networks

Disease Localization in Multilayer Networks

We present a continuous formulation of epidemic spreading on multilayer networks using a tensorial representation, extending the models of monoplex networks to this context. We derive analytical expressions for the epidemic threshold of the SIS and SIR dynamics, as well as upper and lower bounds for the disease prevalence in the steady state for the SIS scenario. Using the quasi-stationary state method we numerically show the existence of disease localization and the emergence of two or more susceptibility peaks, which are characterized analytically and numerically through the inverse participation ratio. Furthermore, when mapping the critical dynamics to an eigenvalue problem, we observe a characteristic transition in the eigenvalue spectra of the supra-contact tensor as a function of the ratio of two spreading rates: if the rate at which the disease spreads within a layer is comparable to the spreading rate across layers, the individual spectra of each layer merge with the coupling between layers. Finally, we verified the barrier effect, i.e., for three-layer configuration, when the layer with the largest eigenvalue is located at the center of the line, it can effectively act as a barrier to the disease. The formalism introduced here provides a unifying mathematical approach to disease contagion in multiplex systems opening new possibilities for the study of spreading processes.Comment: Revised version. 25 pages and 18 figure

Griffiths phases and localization in hierarchical modular networks

We study variants of hierarchical modular network models suggested by Kaiser and Hilgetag [Frontiers in Neuroinformatics, 4 (2010) 8] to model functional brain connectivity, using extensive simulations and quenched mean-field theory (QMF), focusing on structures with a connection probability that decays exponentially with the level index. Such networks can be embedded in two-dimensional Euclidean space. We explore the dynamic behavior of the contact process (CP) and threshold models on networks of this kind, including hierarchical trees. While in the small-world networks originally proposed to model brain connectivity, the topological heterogeneities are not strong enough to induce deviations from mean-field behavior, we show that a Griffiths phase can emerge under reduced connection probabilities, approaching the percolation threshold. In this case the topological dimension of the networks is finite, and extended regions of bursty, power-law dynamics are observed. Localization in the steady state is also shown via QMF. We investigate the effects of link asymmetry and coupling disorder, and show that localization can occur even in small-world networks with high connectivity in case of link disorder.Comment: 18 pages, 20 figures, accepted version in Scientific Report

Relating Topological Determinants of Complex Networks to Their Spectral Properties: Structural and Dynamical Effects

The largest eigenvalue of a network's adjacency matrix and its associated principal eigenvector are key elements for determining the topological structure and the properties of dynamical processes mediated by it. We present a physically grounded expression relating the value of the largest eigenvalue of a given network to the largest eigenvalue of two network subgraphs, considered as isolated: The hub with its immediate neighbors and the densely connected set of nodes with maximum $K$-core index. We validate this formula showing that it predicts with good accuracy the largest eigenvalue of a large set of synthetic and real-world topologies. We also present evidence of the consequences of these findings for broad classes of dynamics taking place on the networks. As a byproduct, we reveal that the spectral properties of heterogeneous networks built according to the linear preferential attachment model are qualitatively different from those of their static counterparts.Comment: 18 pages, 13 figure

A survey on Human Mobility and its applications

Human Mobility has attracted attentions from different fields of studies such as epidemic modeling, traffic engineering, traffic prediction and urban planning. In this survey we review major characteristics of human mobility studies including from trajectory-based studies to studies using graph and network theory. In trajectory-based studies statistical measures such as jump length distribution and radius of gyration are analyzed in order to investigate how people move in their daily life, and if it is possible to model this individual movements and make prediction based on them. Using graph in mobility studies, helps to investigate the dynamic behavior of the system, such as diffusion and flow in the network and makes it easier to estimate how much one part of the network influences another by using metrics like centrality measures. We aim to study population flow in transportation networks using mobility data to derive models and patterns, and to develop new applications in predicting phenomena such as congestion. Human Mobility studies with the new generation of mobility data provided by cellular phone networks, arise new challenges such as data storing, data representation, data analysis and computation complexity. A comparative review of different data types used in current tools and applications of Human Mobility studies leads us to new approaches for dealing with mentioned challenges

Network centrality: an introduction

Centrality is a key property of complex networks that influences the behavior of dynamical processes, like synchronization and epidemic spreading, and can bring important information about the organization of complex systems, like our brain and society. There are many metrics to quantify the node centrality in networks. Here, we review the main centrality measures and discuss their main features and limitations. The influence of network centrality on epidemic spreading and synchronization is also pointed out in this chapter. Moreover, we present the application of centrality measures to understand the function of complex systems, including biological and cortical networks. Finally, we discuss some perspectives and challenges to generalize centrality measures for multilayer and temporal networks.Comment: Book Chapter in "From nonlinear dynamics to complex systems: A Mathematical modeling approach" by Springe