WebChem Viewer: a tool for the easy dissemination of chemical and structural data sets.

BackgroundSharing sets of chemical data (e.g., chemical properties, docking scores, etc.) among collaborators with diverse skill sets is a common task in computer-aided drug design and medicinal chemistry. The ability to associate this data with images of the relevant molecular structures greatly facilitates scientific communication. There is a need for a simple, free, open-source program that can automatically export aggregated reports of entire chemical data sets to files viewable on any computer, regardless of the operating system and without requiring the installation of additional software.ResultsWe here present a program called WebChem Viewer that automatically generates these types of highly portable reports. Furthermore, in designing WebChem Viewer we have also created a useful online web application for remotely generating molecular structures from SMILES strings. We encourage the direct use of this online application as well as its incorporation into other software packages.ConclusionsWith these features, WebChem Viewer enables interdisciplinary collaborations that require the sharing and visualization of small molecule structures and associated sets of heterogeneous chemical data. The program is released under the FreeBSD license and can be downloaded from http://nbcr.ucsd.edu/WebChemViewer. The associated web application (called "Smiley2png 1.0") can be accessed through freely available web services provided by the National Biomedical Computation Resource at http://nbcr.ucsd.edu

Accessible user interface support for multi-device ubiquitous applications: architectural modifiability considerations

The market for personal computing devices is rapidly expanding from PC, to mobile, home entertainment systems, and even the automotive industry. When developing software targeting such ubiquitous devices, the balance between development costs and market coverage has turned out to be a challenging issue. With the rise of Web technology and the Internet of things, ubiquitous applications have become a reality. Nonetheless, the diversity of presentation and interaction modalities still drastically limit the number of targetable devices and the accessibility toward end users. This paper presents webinos, a multi-device application middleware platform founded on the Future Internet infrastructure. Hereto, the platform's architectural modifiability considerations are described and evaluated as a generic enabler for supporting applications, which are executed in ubiquitous computing environments

Integration of blockchains with management information systems

In the era of the fourth industrial revolution (Industry 4.0), many Management Information Systems (MIS) integrate real-time data collection and use technologies such as big data, machine learning, and cloud computing, to foster a wide range of creative innovations, business improvements, and new business models and processes. However, the integration of blockchain with MIS offers the blockchain trilemma of security, decentralisation and scalability. MIS are usually Web 2.0 clientserver applications that include the front end web systems and back end databases; while blockchain systems are Web 3.0 decentralised applications. MIS are usually private systems that a single party controls and manages; while blockchain systems are usually public, and any party can join and participate. This paper clarifies the key concepts and illustrates with figures, the implementation of public, private and consortium blockchains on the Ethereum platform. Ultimately, the paper presents a framework for building a private blockchain system on the public Ethereum blockchain. Then,integrating the Web 2.0 client-server applications that are commonly used in MIS with Web 3.0 decentralised blockchain applications

Staging Transformations for Multimodal Web Interaction Management

Multimodal interfaces are becoming increasingly ubiquitous with the advent of mobile devices, accessibility considerations, and novel software technologies that combine diverse interaction media. In addition to improving access and delivery capabilities, such interfaces enable flexible and personalized dialogs with websites, much like a conversation between humans. In this paper, we present a software framework for multimodal web interaction management that supports mixed-initiative dialogs between users and websites. A mixed-initiative dialog is one where the user and the website take turns changing the flow of interaction. The framework supports the functional specification and realization of such dialogs using staging transformations -- a theory for representing and reasoning about dialogs based on partial input. It supports multiple interaction interfaces, and offers sessioning, caching, and co-ordination functions through the use of an interaction manager. Two case studies are presented to illustrate the promise of this approach.Comment: Describes framework and software architecture for multimodal web interaction managemen

Designing and evaluating the usability of a machine learning API for rapid prototyping music technology

To better support creative software developers and music technologists' needs, and to empower them as machine learning users and innovators, the usability of and developer experience with machine learning tools must be considered and better understood. We review background research on the design and evaluation of application programming interfaces (APIs), with a focus on the domain of machine learning for music technology software development. We present the design rationale for the RAPID-MIX API, an easy-to-use API for rapid prototyping with interactive machine learning, and a usability evaluation study with software developers of music technology. A cognitive dimensions questionnaire was designed and delivered to a group of 12 participants who used the RAPID-MIX API in their software projects, including people who developed systems for personal use and professionals developing software products for music and creative technology companies. The results from the questionnaire indicate that participants found the RAPID-MIX API a machine learning API which is easy to learn and use, fun, and good for rapid prototyping with interactive machine learning. Based on these findings, we present an analysis and characterization of the RAPID-MIX API based on the cognitive dimensions framework, and discuss its design trade-offs and usability issues. We use these insights and our design experience to provide design recommendations for ML APIs for rapid prototyping of music technology. We conclude with a summary of the main insights, a discussion of the merits and challenges of the application of the CDs framework to the evaluation of machine learning APIs, and directions to future work which our research deems valuable

Accessibility of E-Commerce Websites for Vision Impaired Persons

In this thesis accessibility problems with websites for vision-impaired persons are discussed in detail. General accessibility problems and those specific to e-commerce websites,especially on-line shopping websites are discussed. Accessibility problems are analyzed from the perspective of a screen reader user. As a solution for the accessibility problems identified, the WCAG 2.0 guidelines are reviewed and new changes are proposed to improve the existing guidelines. Enhanced solutions using tactile media capable of providing a better web browsing experience for vision-impaired persons are also discussed