An assembly oriented design framework for product structure engineering and assembly sequence planning

The paper describes a novel framework for an assembly-oriented design (AOD) approach as a new functional product lifecycle management (PLM) strategy, by considering product design and assembly sequence planning phases concurrently. Integration issues of product life cycle into the product development process have received much attention over the last two decades, especially at the detailed design stage. The main objective of the research is to define assembly sequence into preliminary design stages by introducing and applying assembly process knowledge in order to provide an assembly context knowledge to support life-oriented product development process, particularly for product structuring. The proposed framework highlights a novel algorithm based on a mathematical model integrating boundary conditions related to DFA rules, engineering decisions for assembly sequence and the product structure definition. This framework has been implemented in a new system called PEGASUS considered as an AOD module for a PLM system. A case study of applying the framework to a catalytic-converter and diesel particulate filter sub-system, belonging to an exhaust system from an industrial automotive supplier, is introduced to illustrate the efficiency of the proposed AOD methodology

Strategic perspectives on modularity

In this paper we argue that the debate on modularity has come to a point where a consensus is slowly emerging. However, we also contend that this consensus is clearly technology driven. In particular, no room is left for firm strategies. Typically, technology is considered as an exogenous variable to which firms have no choices but to adapt. Taking a slightly different perspective, our main objective is to offer a conceptual framework enabling to shed light on the role of corporate strategies in the process of modularization. From interviews with academic design engineers, we show that firms often consider product architecture as a critical variable to fit their strategic requirements. Based on design sciences, we build an original approach to product modularity. This approach, which leaves an important space for firms' strategic choices, proves also to seize a large part of the industrial reality of modularity. Our framework, which is a first step towards the consideration of strategies within the framework of modularity, gives an account for the diversity of industrial logics related to product modularization.product modularity ; corporate strategy ; technological determinism

Pathophysiology, histopathology and therapeutic of SARS-CoV-2

The rapid transmission of SARS-CoV-2 through the world has induced the scientist to understand the histopathology of the virus and then to find an effective drug. However, many of the point associated with the virus pathogenicity still unknown and need more studies. In this chapter the pathophysiology, histopathology and therapeutic of SARS-CoV-2 has been reviewed. It was appeared that pathogenicity of SARS-CoV-2 is belonging to the viral with genome structure which acting by blocking the host innate immune response. Both chloroquine and hydroxyl-chloroquine have similar structure and mechanism action and they are among the most effective antiviral for treating the patents with the SARS-CoV-2. Chloroquine works by inhibition the intracellular organism by increasing the pH

Competitive manufacturing strategies for the manufacturing industries in Turkey

In this study, results of the research into competitive manufacturing strategies of companies in four different sector studies covering 82 companies from the electronics, cement, automotive manufacturers, and appliances part and component suppliers in Turkey are presented. The data used in the study are gathered by conducting four sector surveys in 1997 and 1998 using a questionnaire supported by some follow-up interviews and site visits. A competitive manufacturing strategy is represented here by its components being the competitive priorities, the manufacturing objectives, and the action plans the companies plan to adopt in the near future. The results indicate that the manufacturing industry in Turkey bases its competition strategy mainly on low price, although there is a growing trend towards increasing emphasis on product differentiation. Quality and quality related issues constitute the top priority issues for the manufacturing industries in Turkey with Total Quality Management being the most preferred action plan

SmartUnit: Empirical Evaluations for Automated Unit Testing of Embedded Software in Industry

In this paper, we aim at the automated unit coverage-based testing for embedded software. To achieve the goal, by analyzing the industrial requirements and our previous work on automated unit testing tool CAUT, we rebuild a new tool, SmartUnit, to solve the engineering requirements that take place in our partner companies. SmartUnit is a dynamic symbolic execution implementation, which supports statement, branch, boundary value and MC/DC coverage. SmartUnit has been used to test more than one million lines of code in real projects. For confidentiality motives, we select three in-house real projects for the empirical evaluations. We also carry out our evaluations on two open source database projects, SQLite and PostgreSQL, to test the scalability of our tool since the scale of the embedded software project is mostly not large, 5K-50K lines of code on average. From our experimental results, in general, more than 90% of functions in commercial embedded software achieve 100% statement, branch, MC/DC coverage, more than 80% of functions in SQLite achieve 100% MC/DC coverage, and more than 60% of functions in PostgreSQL achieve 100% MC/DC coverage. Moreover, SmartUnit is able to find the runtime exceptions at the unit testing level. We also have reported exceptions like array index out of bounds and divided-by-zero in SQLite. Furthermore, we analyze the reasons of low coverage in automated unit testing in our setting and give a survey on the situation of manual unit testing with respect to automated unit testing in industry.Comment: In Proceedings of 40th International Conference on Software Engineering: Software Engineering in Practice Track, Gothenburg, Sweden, May 27-June 3, 2018 (ICSE-SEIP '18), 10 page