Computing contrast ratio in medical images using local content information

Rationale Image quality assessment in medical applications is often based on quantifying the visibility between a structure of interest such as a vessel, termed foreground (F) and its surrounding anatomical background (B), i.e., the contrast ratio. A high quality image is the one that is able to make diagnostically relevant details distinguishable from the background. Therefore, the computation of contrast ratio is an important task in automatic medical image quality assessment. Methods We estimate the contrast ratio by using Weber’s law in local image patches. A small image patch can contain a flat area, a textured area or an edge. Regions with edges are characterized by bimodal histograms representing B and F, and the local contrast ratio can be estimated using the ratio between mean intensity values of each mode of the histogram. B and F are identified by computing the mid-value between the modes using the ISODATA algorithm. This process is performed over the entire image with a sliding window resulting in a contrast ratio per pixel. Results We have tested our measure on two general purpose databases (TID2013 [1] and CSIQ [2]) to demonstrate that the proposed measure agrees with human preferences of quality. Since our measure is specifically designed for measuring contrast, only images exhibiting contrast changes are used. The difference between the maximum of the contrast ratios corresponding to the reference and processed images is used as a quality predictor. Human quality scores and our proposed measure are compared with the Pearson correlation coefficient. Our experimental results show that our method is able to accurately predict changes of perceived quality due to contrast decrements (Pearson correlations higher than 90%). Additionally, this method can detect changes in contrast level in interventional x-ray images acquired with varying dose [3]. For instance, the resulting contrast maps demonstrate reduced contrast ratios for vessel edges on X-ray images acquired at lower dose settings, i.e., lower distinguishability from the background, compared to higher dose acquisitions. Conclusions We propose a measure to compute contrast ratio by using Weber’s law in local image patches. While the proposed contrast ratio is computationally simple, this approximation of local content has shown to be useful in measuring quality differences due to contrast decrements in images. Especially, changes in structures of interest due to low contrast ratio can be detected by using the contrast map making our method potentially useful in Xray imaging dose control. References [1] Ponomarenko N. et al., “A New Color Image Database TID2013: Innovations and Results,” Proceedings of ACIVS, 402-413 (2013). [2] Larson E. and Chandler D., "Most apparent distortion: full-reference image quality assessment and the role of strategy," Journal of Electronic Imaging, 19 (1), 2010. [3] Kumcu, A. et al., “Interventional x-ray image quality measure based on a psychovisual detectability model,” MIPS XVI, Ghent, Belgium, 2015

Full Reference Objective Quality Assessment for Reconstructed Background Images

With an increased interest in applications that require a clean background image, such as video surveillance, object tracking, street view imaging and location-based services on web-based maps, multiple algorithms have been developed to reconstruct a background image from cluttered scenes. Traditionally, statistical measures and existing image quality techniques have been applied for evaluating the quality of the reconstructed background images. Though these quality assessment methods have been widely used in the past, their performance in evaluating the perceived quality of the reconstructed background image has not been verified. In this work, we discuss the shortcomings in existing metrics and propose a full reference Reconstructed Background image Quality Index (RBQI) that combines color and structural information at multiple scales using a probability summation model to predict the perceived quality in the reconstructed background image given a reference image. To compare the performance of the proposed quality index with existing image quality assessment measures, we construct two different datasets consisting of reconstructed background images and corresponding subjective scores. The quality assessment measures are evaluated by correlating their objective scores with human subjective ratings. The correlation results show that the proposed RBQI outperforms all the existing approaches. Additionally, the constructed datasets and the corresponding subjective scores provide a benchmark to evaluate the performance of future metrics that are developed to evaluate the perceived quality of reconstructed background images.Comment: Associated source code: https://github.com/ashrotre/RBQI, Associated Database: https://drive.google.com/drive/folders/1bg8YRPIBcxpKIF9BIPisULPBPcA5x-Bk?usp=sharing (Email for permissions at: ashrotreasuedu

Enhancing retinal images by nonlinear registration

Being able to image the human retina in high resolution opens a new era in many important fields, such as pharmacological research for retinal diseases, researches in human cognition, nervous system, metabolism and blood stream, to name a few. In this paper, we propose to share the knowledge acquired in the fields of optics and imaging in solar astrophysics in order to improve the retinal imaging at very high spatial resolution in the perspective to perform a medical diagnosis. The main purpose would be to assist health care practitioners by enhancing retinal images and detect abnormal features. We apply a nonlinear registration method using local correlation tracking to increase the field of view and follow structure evolutions using correlation techniques borrowed from solar astronomy technique expertise. Another purpose is to define the tracer of movements after analyzing local correlations to follow the proper motions of an image from one moment to another, such as changes in optical flows that would be of high interest in a medical diagnosis.Comment: 21 pages, 7 figures, submitted to Optics Communication

No-reference image quality assessment through the von Mises distribution

An innovative way of calculating the von Mises distribution (VMD) of image entropy is introduced in this paper. The VMD's concentration parameter and some fitness parameter that will be later defined, have been analyzed in the experimental part for determining their suitability as a image quality assessment measure in some particular distortions such as Gaussian blur or additive Gaussian noise. To achieve such measure, the local R\'{e}nyi entropy is calculated in four equally spaced orientations and used to determine the parameters of the von Mises distribution of the image entropy. Considering contextual images, experimental results after applying this model show that the best-in-focus noise-free images are associated with the highest values for the von Mises distribution concentration parameter and the highest approximation of image data to the von Mises distribution model. Our defined von Misses fitness parameter experimentally appears also as a suitable no-reference image quality assessment indicator for no-contextual images.Comment: 29 pages, 11 figure