Effectively Quantifying the Performance of Lower-Limb Exoskeletons Over a Range of Walking Conditions

Exoskeletons and other wearable robotic devices have a wide range of potential applications, including assisting patients with walking pathologies, acting as tools for rehabilitation, and enhancing the capabilities of healthy humans. However, applying these devices effectively in a real-world setting can be challenging, as the optimal design features and control commands for an exoskeleton are highly dependent on the current user, task and environment. Consequently, robust metrics and methods for quantifying exoskeleton performance are required. This work presents an analysis of walking data collected for healthy subjects walking with an active pelvis exoskeleton over three assistance scenarios and five walking contexts. Spatial and temporal, kinematic, kinetic and other novel dynamic gait metrics were compared to identify which metrics exhibit desirable invariance properties, and so are good candidates for use as a stability metric over varying walking conditions. Additionally, using a model-based approach, the average metabolic power consumption was calculated for a subset of muscles crossing the hip, knee and ankle joints, and used to analyse how the energy-reducing properties of an exoskeleton are affected by changes in walking context. The results demonstrated that medio-lateral centre of pressure displacement and medio-lateral margin of stability exhibit strong invariance to changes in walking conditions. This suggests that these dynamic gait metrics are optimised in human gait and are potentially suitable metrics for optimising in an exoskeleton control paradigm. The effectiveness of the exoskeleton at reducing human energy expenditure was observed to increase when walking on an incline, where muscles aiding in hip flexion were assisted, but decrease when walking at a slow speed. These results underline the need for adaptive control algorithms for exoskeletons if they are to be used in varied environments

Exoskeleton-assisted locomotion: design, control and evaluation of wearable robotic devices

Assistive robotic devices such as exoskeletons and prosthetic limbs have great potential as tools for both augmentation and rehabilitation. However, due to the complexity of controlling these devices, especially in unstructured environments where factors such as walking speed and incline can vary rapidly, it is uncommon to see exoskeletons outside of a clinical or research setting. Prostheses, whilst more common, are typically passive, which limits their ability to match the push off forces associated with healthy gait. Motivated by modern techniques for controlling legged robots, this thesis motivates the pursuit of an optimisation-based approach to the control and design of exoskeletons. We identify a number of open problems within the field, namely (1) how to model the dynamic interaction between a human subject and an attached exoskeleton; (2) identifying the appropriate metric or combination of metrics to optimise for in exoskeleton-assisted locomotion; and (3) how to account for changes in human walking style induced by the presence of external assistive forces. This thesis details attempts to solve each of these problems. We present a methodology for expressing human-exoskeleton system models as a combination of musculoskeletal models, exoskeleton inertial parameters and constraint forces. A specific human-exoskeleton model is detailed, along with a range of methods for modelling the interaction forces which occur at the attachment points between the human and exoskeleton agents. Experimental motion data is analysed using musculoskeletal modelling software (OpenSim) to quantify the effect that each of these interaction models, which represent various degrees of approximation, have on the resulting humanexoskeleton dynamics. Applying exoskeleton assistance is inherently a shared control problem. The overall goal is not to achieve a prescribed motion at any cost, or to do so while minimising exoskeleton joint torques, but rather to enhance aspects of the assisted humans motions; for example, increasing energy efficiency or stability. Therefore, in order to optimise exoskeleton control patterns we must first consider what it means for the resultant gait patterns to be optimal, or even good. We present a detailed analysis of exoskeleton-assisted walking in healthy subjects, with a particular focus on identifying those metrics which are invariant to changes in walking condition (e.g. walking speed or incline). We posit that such metrics, which exhibit strong invariance properties, are good candidates for the objective function of an optimisation-based controller. Human walking strategies are unique and complex, and the problem of predicting the effect of exoskeleton assistance on a subjects gait pattern is a challenging one. In recent years, success has been had by methods which aim to learn suitable assistance strategies directly from a subject, via a process known as human-in-the-loop optimisation. We present a novel humanin- the-loop framework which utilises musculoskeletal modelling to make the learning process more time-efficient. Our method is evaluated on a number of subjects walking on a treadmill with exoskeleton assistance. In addition, we also explore how human-in-the-loop optimisation can be used to inform the design of exoskeletons to enhance their assistive capabilities. Overall, these contributions represent a step towards enabling the wider usage of exoskeletons and other assistive robotic devices, which could lead to significant improvements to quality of life for many

Human Activity Recognition and Control of Wearable Robots

abstract: Wearable robotics has gained huge popularity in recent years due to its wide applications in rehabilitation, military, and industrial fields. The weakness of the skeletal muscles in the aging population and neurological injuries such as stroke and spinal cord injuries seriously limit the abilities of these individuals to perform daily activities. Therefore, there is an increasing attention in the development of wearable robots to assist the elderly and patients with disabilities for motion assistance and rehabilitation. In military and industrial sectors, wearable robots can increase the productivity of workers and soldiers. It is important for the wearable robots to maintain smooth interaction with the user while evolving in complex environments with minimum effort from the user. Therefore, the recognition of the user's activities such as walking or jogging in real time becomes essential to provide appropriate assistance based on the activity. This dissertation proposes two real-time human activity recognition algorithms intelligent fuzzy inference (IFI) algorithm and Amplitude omega ($A \omega$) algorithm to identify the human activities, i.e., stationary and locomotion activities. The IFI algorithm uses knee angle and ground contact forces (GCFs) measurements from four inertial measurement units (IMUs) and a pair of smart shoes. Whereas, the $A \omega$ algorithm is based on thigh angle measurements from a single IMU. This dissertation also attempts to address the problem of online tuning of virtual impedance for an assistive robot based on real-time gait and activity measurement data to personalize the assistance for different users. An automatic impedance tuning (AIT) approach is presented for a knee assistive device (KAD) in which the IFI algorithm is used for real-time activity measurements. This dissertation also proposes an adaptive oscillator method known as amplitude omega adaptive oscillator ($A\omega AO$) method for HeSA (hip exoskeleton for superior augmentation) to provide bilateral hip assistance during human locomotion activities. The $A \omega$ algorithm is integrated into the adaptive oscillator method to make the approach robust for different locomotion activities. Experiments are performed on healthy subjects to validate the efficacy of the human activities recognition algorithms and control strategies proposed in this dissertation. Both the activity recognition algorithms exhibited higher classification accuracy with less update time. The results of AIT demonstrated that the KAD assistive torque was smoother and EMG signal of Vastus Medialis is reduced, compared to constant impedance and finite state machine approaches. The $A\omega AO$ method showed real-time learning of the locomotion activities signals for three healthy subjects while wearing HeSA. To understand the influence of the assistive devices on the inherent dynamic gait stability of the human, stability analysis is performed. For this, the stability metrics derived from dynamical systems theory are used to evaluate unilateral knee assistance applied to the healthy participants.Dissertation/ThesisDoctoral Dissertation Aerospace Engineering 201

Effects of a soft robotic exosuit on the quality and speed of overground walking depends on walking ability after stroke

\ua9 2023, BioMed Central Ltd., part of Springer Nature.Background: Soft robotic exosuits can provide partial dorsiflexor and plantarflexor support in parallel with paretic muscles to improve poststroke walking capacity. Previous results indicate that baseline walking ability may impact a user’s ability to leverage the exosuit assistance, while the effects on continuous walking, walking stability, and muscle slacking have not been evaluated. Here we evaluated the effects of a portable ankle exosuit during continuous comfortable overground walking in 19 individuals with chronic hemiparesis. We also compared two speed-based subgroups (threshold: 0.93 m/s) to address poststroke heterogeneity. Methods: We refined a previously developed portable lightweight soft exosuit to support continuous overground walking. We compared five minutes of continuous walking in a laboratory with the exosuit to walking without the exosuit in terms of ground clearance, foot landing and propulsion, as well as the energy cost of transport, walking stability and plantarflexor muscle slacking. Results: Exosuit assistance was associated with improvements in the targeted gait impairments: 22% increase in ground clearance during swing, 5\ub0 increase in foot-to-floor angle at initial contact, and 22% increase in the center-of-mass propulsion during push-off. The improvements in propulsion and foot landing contributed to a 6.7% (0.04 m/s) increase in walking speed (R 2 = 0.82). This enhancement in gait function was achieved without deterioration in muscle effort, stability or cost of transport. Subgroup analyses revealed that all individuals profited from ground clearance support, but slower individuals leveraged plantarflexor assistance to improve propulsion by 35% to walk 13% faster, while faster individuals did not change either. Conclusions: The immediate restorative benefits of the exosuit presented here underline its promise for rehabilitative gait training in poststroke individuals

System Identification of Bipedal Locomotion in Robots and Humans

The ability to perform a healthy walking gait can be altered in numerous cases due to gait disorder related pathologies. The latter could lead to partial or complete mobility loss, which affects the patients’ quality of life. Wearable exoskeletons and active prosthetics have been considered as a key component to remedy this mobility loss. The control of such devices knows numerous challenges that are yet to be addressed. As opposed to fixed trajectories control, real-time adaptive reference generation control is likely to provide the wearer with more intent control over the powered device. We propose a novel gait pattern generator for the control of such devices, taking advantage of the inter-joint coordination in the human gait. Our proposed method puts the user in the control loop as it maps the motion of healthy limbs to that of the affected one. To design such control strategy, it is critical to understand the dynamics behind bipedal walking. We begin by studying the simple compass gait walker. We examine the well-known Virtual Constraints method of controlling bipedal robots in the image of the compass gait. In addition, we provide both the mechanical and control design of an affordable research platform for bipedal dynamic walking. We then extend the concept of virtual constraints to human locomotion, where we investigate the accuracy of predicting lower limb joints angular position and velocity from the motion of the other limbs. Data from nine healthy subjects performing specific locomotion tasks were collected and are made available online. A successful prediction of the hip, knee, and ankle joints was achieved in different scenarios. It was also found that the motion of the cane alone has sufficient information to help predict good trajectories for the lower limb in stairs ascent. Better estimates were obtained using additional information from arm joints. We also explored the prediction of knee and ankle trajectories from the motion of the hip joints

Gait Cycle-Inspired Learning Strategy for Continuous Prediction of Knee Joint Trajectory from sEMG

Predicting lower limb motion intent is vital for controlling exoskeleton robots and prosthetic limbs. Surface electromyography (sEMG) attracts increasing attention in recent years as it enables ahead-of-time prediction of motion intentions before actual movement. However, the estimation performance of human joint trajectory remains a challenging problem due to the inter- and intra-subject variations. The former is related to physiological differences (such as height and weight) and preferred walking patterns of individuals, while the latter is mainly caused by irregular and gait-irrelevant muscle activity. This paper proposes a model integrating two gait cycle-inspired learning strategies to mitigate the challenge for predicting human knee joint trajectory. The first strategy is to decouple knee joint angles into motion patterns and amplitudes former exhibit low variability while latter show high variability among individuals. By learning through separate network entities, the model manages to capture both the common and personalized gait features. In the second, muscle principal activation masks are extracted from gait cycles in a prolonged walk. These masks are used to filter out components unrelated to walking from raw sEMG and provide auxiliary guidance to capture more gait-related features. Experimental results indicate that our model could predict knee angles with the average root mean square error (RMSE) of 3.03(0.49) degrees and 50ms ahead of time. To our knowledge this is the best performance in relevant literatures that has been reported, with reduced RMSE by at least 9.5%

Biomechatronics: Harmonizing Mechatronic Systems with Human Beings

This eBook provides a comprehensive treatise on modern biomechatronic systems centred around human applications. A particular emphasis is given to exoskeleton designs for assistance and training with advanced interfaces in human-machine interaction. Some of these designs are validated with experimental results which the reader will find very informative as building-blocks for designing such systems. This eBook will be ideally suited to those researching in biomechatronic area with bio-feedback applications or those who are involved in high-end research on manmachine interfaces. This may also serve as a textbook for biomechatronic design at post-graduate level

Adaptive Controllers for Assistive Robotic Devices

Lower extremity assistive robotic devices, such as exoskeletons and prostheses, have the potential to improve mobility for millions of individuals, both healthy and disabled. These devices are designed to work in conjunction with the user to enhance or replace lost functionality of a limb. Given the large variability in walking dynamics from person to person, it is still an open research question of how to optimally control such devices to maximize their benefit for each individual user. In this context, it is becoming more and more evident that there exists no "one size fits all" solution, but that each device needs to be tuned on a subject-specific basis to best account for each user's unique gait characteristics. However, the controllers that run in the background of these devices to dictate when and what type of actuation to deliver often have up to a hundred different parameters that can be tuned on a subject-specific basis. To hand tune each parameter can be an extremely tedious and time consuming process. Additionally, current tuning practices often rely on subjective measures to inform the fitting process. To address the current obstacles associated with device control and tuning, I have developed novel tools that overcome some of these issues through the design of control architectures that autonomously adapt to the user based upon real-time physiological measures. This approach frames the tuning process of a device as a real-time optimization and allows for the device to co-adapt with the wearer during use. As an outcome of these approaches, I have been able to investigate what qualities of a device controller are beneficial to users through the analysis of whole body kinematics, dynamics, and energetics. The framework of my research has been broken down into four major projects. First, I investigated how current standards of processing and analyzing physiological measures could be improved upon. Specifically, I focused on how to analyze non-steady-state measures of metabolic work rate in real time and how the noise content of theses measures can inform confidence analyses. Second, I applied the techniques I developed for analyzing non-steady-state measures of metabolic work rate to conduct a real-time optimization of powered bilateral ankle exoskeletons. For this study I employed a gradient descent optimization to tune and optimize an actuation timing parameter of these simple exoskeletons on a subject-specific basis. Third, I investigated how users may use an adaptive controller where they had a more direct impact on the adaptation via their own muscle recruitment. In this study, I designed and tested an adaptive gain proportional myoelectric controller with healthy subjects walking in bilateral ankle exoskeletons. Through this work I showed that subjects adapted to using increased levels of total ankle power compared to unpowered walking in the devices. As a result, subjects decreased power at their hip and were able to achieve large decreases in their metabolic work rate compared to unpowered walking. Fourth, I compared how subjects may use a controller driven by neural signals differently than one driven by mechanically intrinsic signals. The results of this project suggest that control based on neural signals may be better suited for therapeutic rehabilitation than control based on mechanically intrinsic signals. Together, these four projects have drastically improved upon subject-specific control of assistive devices in both a research and clinical setting.PHDMechanical EngineeringUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttps://deepblue.lib.umich.edu/bitstream/2027.42/144029/1/jrkoller_1.pd