Analysis of Vocal Disorders in a Feature Space

This paper provides a way to classify vocal disorders for clinical applications. This goal is achieved by means of geometric signal separation in a feature space. Typical quantities from chaos theory (like entropy, correlation dimension and first lyapunov exponent) and some conventional ones (like autocorrelation and spectral factor) are analysed and evaluated, in order to provide entries for the feature vectors. A way of quantifying the amount of disorder is proposed by means of an healthy index that measures the distance of a voice sample from the centre of mass of both healthy and sick clusters in the feature space. A successful application of the geometrical signal separation is reported, concerning distinction between normal and disordered phonation.Comment: 12 pages, 3 figures, accepted for publication in Medical Engineering & Physic

Empowering and assisting natural human mobility: The simbiosis walker

This paper presents the complete development of the Simbiosis Smart Walker. The device is equipped with a set of sensor subsystems to acquire user-machine interaction forces and the temporal evolution of user's feet during gait. The authors present an adaptive filtering technique used for the identification and separation of different components found on the human-machine interaction forces. This technique allowed isolating the components related with the navigational commands and developing a Fuzzy logic controller to guide the device. The Smart Walker was clinically validated at the Spinal Cord Injury Hospital of Toledo - Spain, presenting great acceptability by spinal chord injury patients and clinical staf

Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection

Background: Voice disorders affect patients profoundly, and acoustic tools can potentially measure voice function objectively. Disordered sustained vowels exhibit wide-ranging phenomena, from nearly periodic to highly complex, aperiodic vibrations, and increased "breathiness". Modelling and surrogate data studies have shown significant nonlinear and non-Gaussian random properties in these sounds. Nonetheless, existing tools are limited to analysing voices displaying near periodicity, and do not account for this inherent biophysical nonlinearity and non-Gaussian randomness, often using linear signal processing methods insensitive to these properties. They do not directly measure the two main biophysical symptoms of disorder: complex nonlinear aperiodicity, and turbulent, aeroacoustic, non-Gaussian randomness. Often these tools cannot be applied to more severe disordered voices, limiting their clinical usefulness.

Methods: This paper introduces two new tools to speech analysis: recurrence and fractal scaling, which overcome the range limitations of existing tools by addressing directly these two symptoms of disorder, together reproducing a "hoarseness" diagram. A simple bootstrapped classifier then uses these two features to distinguish normal from disordered voices.

Results: On a large database of subjects with a wide variety of voice disorders, these new techniques can distinguish normal from disordered cases, using quadratic discriminant analysis, to overall correct classification performance of 91.8% plus or minus 2.0%. The true positive classification performance is 95.4% plus or minus 3.2%, and the true negative performance is 91.5% plus or minus 2.3% (95% confidence). This is shown to outperform all combinations of the most popular classical tools.

Conclusions: Given the very large number of arbitrary parameters and computational complexity of existing techniques, these new techniques are far simpler and yet achieve clinically useful classification performance using only a basic classification technique. They do so by exploiting the inherent nonlinearity and turbulent randomness in disordered voice signals. They are widely applicable to the whole range of disordered voice phenomena by design. These new measures could therefore be used for a variety of practical clinical purposes.
&#xa

Dysphagia Management and Research in an Acute-Care Military Treatment Facility: The Role of Applied Informatics

Purpose: This report describes the development and preliminary analysis of a database for traumatically injured military service members with dysphagia. Methods: A multidimensional database was developed to capture clinical variables related to swallowing. Data were derived from clinical records and instrumental swallow studies, and ranged from demographics, injury characteristics, swallowing biomechanics, medications, and standardized tools (e.g.. Glasgow Coma Scale, Penetration-Aspiration Scale). Bayesian Belief Network modeling was used to analyze the data at intermediate points, guide data collection, and predict outcomes. Predictive models were validated with independent data via receiver operating characteristic curves. Results: The first iteration of the model (n = 48) revealed variables that could be collapsed for the second model (n = 96). The ability to predict recovery from dysphagia improved from the second to third models (area under the curve = 0.68 to 0.86). The third model, based on 161 cases, revealed “initial diet restrictions” as first-degree, and “Glasgow Coma Scale, intubation history, and diet change” as second-degree associates for diet restrictions at discharge. Conclusion: This project demonstrates the potential for bioinformatics to advance understanding of dysphagia. This database in concert with Bayesian Belief Network modeling makes it possible to explore predictive relationships between injuries and swallowing function, individual variability in recovery, and appropriate treatment options

Work-related Musculoskeletal Disorders

Work-related musculoskeletal disorders (WRMSDs) refer to a wide range of inflammatory and degenerative conditions that occur in the workplace or are caused by work activities. WRMSDs affect the muscles, tendons, ligaments, joints, peripheral nerves, and supporting blood vessels. These conditions can cause pain and functional impairment and they often result in direct economic costs to both the workplace and the worker. Injuries sustained at work can negatively affect a person's physical and mental health as well as a company's bottom line. This book describes the human musculoskeletal system, including such topics as anthropometry and posture, as it relates to accidents and injuries in the workplace. Chapters discuss such subjects as job standards; risk assessment; direct and indirect costs of WRMSDs; epidemiology, etiology, and pathology of WRMSDs; engineering and administrative controls; risk factor identification; injury management; and education and training. It presents a holistic approach to identifying, intervening, and preventing WRMSDs

A Methodology for Detecting Musculoskeletal Disorders in Industrial Workplaces Using a Mapping Representation of Risk

A correct identification of ergonomic risks and their physical location in production areas becomes vital for the prevention of work-related illnesses. The method proposed for detecting musculoskeletal disorders (MSDs) in industrial workplaces has the objective of identifying the relationship between the workplace design and the nonergonomic task content. A mapping of work conditions was implemented to develop a diagnosis about hazards and ergonomic risk factors present in the work system. The information collected was organized in an ergonomic risk map with the following structure: inputs, information about risks and hazards, process, information about how the risk exposure leads to MSDs and outputs, and information about the consequences of risk factor exposure. The mapping results allowed determining the causes of work-related illnesses in activities of polishing and screening metals, establishing as a main cause of risk the barrel height (1.70 m) that forces the material handling above the shoulders. Force demands required to perform the task (around 277 N in each lifting) were determined. The work-related illnesses identified were low back injuries and rotator cuff injures. The information contained in the map improves the understanding of employers and workers about the origin of ergonomic problems and supports the decision-making about improvement projects focused on risk elimination

Fitting a biomechanical model of the folds to high-speed video data through bayesian estimation

High-speed video recording of the vocal folds during sustained phonation has become a widespread diagnostic tool, and the development of imaging techniques able to perform automated tracking and analysis of relevant glottal cues, such as folds edge position or glottal area, is an active research field. In this paper, a vocal folds vibration analysis method based on the processing of visual data through a biomechanical model of the layngeal dynamics is proposed. The procedure relies on a Bayesian non-stationary estimation of the biomechanical model parameters and state, to fit the folds edge position extracted from the high-speed video endoscopic data. This finely tuned dynamical model is then used as a state transition model in a Bayesian setting, and it allows to obtain a physiologically motivated estimation of upper and lower vocal folds edge position. Based on model prediction, an hypothesis on the lower fold position can be made even in complete fold occlusion conditions occurring during the end of the closed phase and the beginning of the open phase of the glottal cycle. To demonstrate the suitability of the procedure, the method is assessed on a set of audiovisual recordings featuring high-speed video endoscopic data from healthy subjects producing sustained voiced phonation with different laryngeal settings

Models and Analysis of Vocal Emissions for Biomedical Applications

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies