Positive allosteric binding behavior of pyrene-appended triazole-modified thiacalix[4]arene-based fluorescent receptors

The novel heteroditopic receptors 5a∼c have been synthesized, which bear a thiacalix[4]arene in the 1,3-alternate conformation. Two urea moieties possessing various aryl groups with either electron-donating or -withdrawing groups at their p-positions function as anion-binding sites. At the opposite side of the cavity are two pyrene-appended triazole rings, which act as cation-binding sites. The binding property of receptor 5c was investigated by means of 1H NMR and UV–vis spectroscopy and by fluorescence titration experiments in the presence of various transition metal cations and anions in CH2Cl2–DMSO (10:1, v/v) solution. Interestingly, it was found that receptor 5c possessing two p-nitrophenyl ureido moieties, most efficiently complexes in the urea cavity or bistriazoles; the plausible allosteric effect of receptor 5c was also investigated

1º Congresso Internacional de Geologia de Timor-Leste.

Congresso Internacional de Geologia de Timor-Lest

The Sir Anthony Mamo Oncology Centre

In 2009, the development of a medical brief, effectively detailing the specifications for a purpose-built oncology hospital and including the medical equipment and human resources required, was commenced. Robust engagement by the relevant stakeholders, many of which hailed from the extant Sir Paul Boffa Hospital, ensured a very relevant proposal. The project (ERDF 196), led by the Foundation for Medical Sciences, was subsequently approved for partial funding through European Regional Development Funds. The new Sir Anthony Mamo Oncology Centre, as it came to be named, first opened its doors for service in December 2014 when the Out-patients Department received the first oncology patients. In April 2015, this was extended to include haematology and paediatric oncology patients. Full migration of services, including in-patient care, took place in September 2015. The distribution of services within the new Centre includes five clinical areas for in-patients made up of two oncology wards, one radioisotope unit, one haematology ward and one palliative care ward, with a total of 88 beds, an out-patient unit with 12 clinic rooms, a day area for day-treatment with a total of 21 couches and eight beds, a clinical support services unit and a radiotherapy department.peer-reviewe

Rigid Origami Vertices: Conditions and Forcing Sets

We develop an intrinsic necessary and sufficient condition for single-vertex origami crease patterns to be able to fold rigidly. We classify such patterns in the case where the creases are pre-assigned to be mountains and valleys as well as in the unassigned case. We also illustrate the utility of this result by applying it to the new concept of minimal forcing sets for rigid origami models, which are the smallest collection of creases that, when folded, will force all the other creases to fold in a prescribed way

Guest editorial special issue on Electrical discharges in vacuum

The 27 papers in this special issue are expanded versions of selected papers presented at the 23rd International Symposium on Discharges and Electrical Insulation in Vacuum (ISDEIV), held in Bucharest, Romania, on September 15-19, 2008

Playing with the future: social irrealism and the politics of aesthetics

In this paper we wish to explore the political possibilities of video games. Numerous scholars now take seriously the place of popular culture in the remaking of our geographies, but video games still lag behind. For us, this tendency reflects a general response to them as imaginary spaces that are separate from everyday life and 'real' politics. It is this disconnect between abstraction and lived experience that we complicate by defining play as an event of what Brian Massumi calls lived abstraction. We wish to short-circuit the barriers that prevent the aesthetic resonating with the political and argue that through their enactment, video games can animate fantastical futures that require the player to make, and reflect upon, profound ethical decisions that can be antagonistic to prevailing political imaginations. We refer to this as social irrealism to demonstrate that reality can be understood through the impossible and the imagined

Boston University Chamber Ensemble, November 5, 2009

This is the concert program of the Boston University Chamber Ensemble performance on Thurday, November 5, 2009 at 7:30 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts. Works performed were Chacony in G minor by Henry Purcell, Cello Concerto in C minor, RV 401 by Antonio Vivaldi, Fantasia on Greensleeves by Ralph Vaughan Williams, and Symphony No. 21 in A major, K. 134 by Wolfgang Amadeus Mozart. Digitization for Boston University Concert Programs was supported by the Boston University Center for the Humanities Library Endowed Fund

Impact Factor: outdated artefact or stepping-stone to journal certification?

A review of Garfield's journal impact factor and its specific implementation as the Thomson Reuters Impact Factor reveals several weaknesses in this commonly-used indicator of journal standing. Key limitations include the mismatch between citing and cited documents, the deceptive display of three decimals that belies the real precision, and the absence of confidence intervals. These are minor issues that are easily amended and should be corrected, but more substantive improvements are needed. There are indications that the scientific community seeks and needs better certification of journal procedures to improve the quality of published science. Comprehensive certification of editorial and review procedures could help ensure adequate procedures to detect duplicate and fraudulent submissions.Comment: 25 pages, 12 figures, 6 table

Guest Editorial Disruptive Beam-Steering Antenna Technologies for Emerging and Future Satellite Services

The papers in this special section focus on the state-of-the-art of applied and analytical research, including the latest technological advancements and the use of innovative materials and methods to disrupt the way beam-steering antennas are designed and to reveal novel approaches for the design and analysis of antennas for the next generation of satellite communication systems