37 research outputs found

    A Novel Framework for Interactive Visualization and Analysis of Hyperspectral Image Data

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    Edge detection in multispectral images using the n-dimensional self-organizing map

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    We propose a new method for performing edge detection in multi-spectral images based on the self-organizing map (SOM) concept. Previously, 1-dimensional or 2-dimensional SOMs were trained to provide a linear mapping of high-dimensional multispectral vectors. Then, edge detection was applied on that mapping. However, the 1-dimensional SOM may not converge on a suitable global order for images with rich content. Likewise, the 2-dimensional SOM intro-duces false edges due to linearization artifacts. Our method feeds the edge detector without linearization. Instead, it exploits directly the distances of SOM neurons. This avoids the aforementioned draw-backs and is more general, as a SOM of arbitrary dimensionality can be used. We show that our method achieves significantly bet-ter edge detection results than previous work on a high-resolution multispectral image database. Index Terms — Multispectral imaging, Image edge detection, Self organizing feature maps, Machine Visio

    Community-driven approaches to open source archaeological imaging

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    Optical Methods in Sensing and Imaging for Medical and Biological Applications

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    The recent advances in optical sources and detectors have opened up new opportunities for sensing and imaging techniques which can be successfully used in biomedical and healthcare applications. This book, entitled ‘Optical Methods in Sensing and Imaging for Medical and Biological Applications’, focuses on various aspects of the research and development related to these areas. The book will be a valuable source of information presenting the recent advances in optical methods and novel techniques, as well as their applications in the fields of biomedicine and healthcare, to anyone interested in this subject

    OCM 2013 - 1st International Conference on Optical Characterization of Materials: March 6th - 7th, 2013, Karlsruhe, Germany

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    The state of the art in optical characterization of materials is advancing rapidly. New insights into the theoretical foundations of this research field have been gained and exciting practical developments have taken place, both driven by novel applications that are constantly emerging. This book presents latest research results in the domain of Characterization of Materials by spectral characteristics of UV (240 nm) to IR (14 µm), multispectral image analysis, X-Ray, polarimetry and microscopy

    OCM 2013 - Optical Characterization of Materials - conference proceedings

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    The state of the art in optical characterization of materials is advancing rapidly. New insights into the theoretical foundations of this research field have been gained and exciting practical developments have taken place, both driven by novel applications that are constantly emerging. This book presents latest research results in the domain of Characterization of Materials by spectral characteristics of UV (240 nm) to IR (14 µm), multispectral image analysis, X-Ray, polarimetry and microscopy

    Hyperspectral Image Unmixing Incorporating Adjacency Information

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    While the spectral information contained in hyperspectral images is rich, the spatial resolution of such images is in many cases very low. Many pixel spectra are mixtures of pure materials’ spectra and therefore need to be decomposed into their constituents. This work investigates new decomposition methods taking into account spectral, spatial and global 3D adjacency information. This allows for faster and more accurate decomposition results

    Methods and algorithms for quantitative analysis of metallomic images to assess traumatic brain injury

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    The primary aim of this thesis is to develop image processing algorithms to quantitatively determine the link between traumatic brain injury (TBI) severity and chronic traumatic encephalopathy (CTE) neuropathology, specifically looking into the role of blood-brain barrier disruption following TBI. In order to causally investigate the relationship between the tau protein neurodegenerative disease CTE and TBI, mouse models of blast neurotrauma (BNT) and impact neurotrauma (INT) are investigated. First, a high-speed video tracking algorithm is developed based on K-means clustering, active contours and Kalman filtering to comparatively study the head kinematics in blast and impact experiments. Then, to compare BNT and INT neuropathology, methods for quantitative analysis of macroscopic optical images and fluorescent images are described. The secondary aim of this thesis focuses on developing methods for a novel application of metallomic imaging mass spectrometry (MIMS) to biological tissue. Unlike traditional modalities used to assess neuropathology, that suffer from limited sensitivity and analytical capacity, MIMS uses a mass spectrometer -- an analytical instrument for measuring elements and isotopes with high dynamic range, sensitivity and specificity -- as the imaging sensor to generate spatial maps with spectral (vector-valued) data per pixel. Given the vector nature of MIMS data, a unique end-to-end processing pipeline is designed to support data acquisition, visualization and interpretation. A novel multi-modal and multi-channel image registration (MMMCIR) method using multi-variate mutual information as a similarity metric is developed in order to establish correspondence between two images of arbitrary modality. The MMMCIR method is then used to automatically segment MIMS images of the mouse brain and systematically evaluate the levels of relevant elements and isotopes after experimental closed-head impact injury on the impact side (ipsilateral) and opposing side (contralateral) of the brain. This method quantifiably confirms observed differences in gadolinium levels for a cohort of images. Finally, MIMS images of human lacrimal sac biopsy samples are used for preliminary clinicopathological assessments, supporting the utility of the unique insights MIMS provides by correlating areas of inflammation to areas of elevated toxic metals. The image processing methods developed in this work demonstrate the significant capabilities of MIMS and its role in enhancing our understanding of the underlying pathological mechanisms of TBI and other medical conditions.2019-07-09T00:00:00
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