52 research outputs found

    Folding tools for flat conductor cable harnesses

    Get PDF
    Vise grip pliers have detachable metal gripping plates which are changed to accommodate cables from 1 to 3 in. wide and to form any desired fold angle. A second tool squeezes cable along crease to complete the fold

    Seating tool for preparing molded-plug terminations on FCC

    Get PDF
    Hand-operated tool positions and seats window piece and conductor spacer onto conductors of two stripped cables during process of terminating cables with molded plug. Tool accommodates cables up to 3 in. wide and is used in conjunction with folding tools

    From RNA folding to inverse folding: a computational study: Folding and design of RNA molecules

    Get PDF
    Since the discovery of the structure of DNA in the early 1953s and its double-chained complement of information hinting at its means of replication, biologists have recognized the strong connection between molecular structure and function. In the past two decades, there has been a surge of research on an ever-growing class of RNA molecules that are non-coding but whose various folded structures allow a diverse array of vital functions. From the well-known splicing and modification of ribosomal RNA, non-coding RNAs (ncRNAs) are now known to be intimately involved in possibly every stage of DNA translation and protein transcription, as well as RNA signalling and gene regulation processes. Despite the rapid development and declining cost of modern molecular methods, they typically can only describe ncRNA's structural conformations in vitro, which differ from their in vivo counterparts. Moreover, it is estimated that only a tiny fraction of known ncRNAs has been documented experimentally, often at a high cost. There is thus a growing realization that computational methods must play a central role in the analysis of ncRNAs. Not only do computational approaches hold the promise of rapidly characterizing many ncRNAs yet to be described, but there is also the hope that by understanding the rules that determine their structure, we will gain better insight into their function and design. Many studies revealed that the ncRNA functions are performed by high-level structures that often depend on their low-level structures, such as the secondary structure. This thesis studies the computational folding mechanism and inverse folding of ncRNAs at the secondary level. In this thesis, we describe the development of two bioinformatic tools that have the potential to improve our understanding of RNA secondary structure. These tools are as follows: (1) RAFFT for efficient prediction of pseudoknot-free RNA folding pathways using the fast Fourier transform (FFT)}; (2) aRNAque, an evolutionary algorithm inspired by Lévy flights for RNA inverse folding with or without pseudoknot (A secondary structure that often poses difficulties for bio-computational detection). The first tool, RAFFT, implements a novel heuristic to predict RNA secondary structure formation pathways that has two components: (i) a folding algorithm and (ii) a kinetic ansatz. When considering the best prediction in the ensemble of 50 secondary structures predicted by RAFFT, its performance matches the recent deep-learning-based structure prediction methods. RAFFT also acts as a folding kinetic ansatz, which we tested on two RNAs: the CFSE and a classic bi-stable sequence. In both test cases, fewer structures were required to reproduce the full kinetics, whereas known methods (such as Treekin) required a sample of 20,000 structures and more. The second tool, aRNAque, implements an evolutionary algorithm (EA) inspired by the Lévy flight, allowing both local global search and which supports pseudoknotted target structures. The number of point mutations at every step of aRNAque's EA is drawn from a Zipf distribution. Therefore, our proposed method increases the diversity of designed RNA sequences and reduces the average number of evaluations of the evolutionary algorithm. The overall performance showed improved empirical results compared to existing tools through intensive benchmarks on both pseudoknotted and pseudoknot-free datasets. In conclusion, we highlight some promising extensions of the versatile RAFFT method to RNA-RNA interaction studies. We also provide an outlook on both tools' implications in studying evolutionary dynamics

    The urban commuter cyclist trousers design with a sustainable design approach

    Get PDF
    After the prolonged COVID-19 pandemic, we have entered the New Normal phase with all adjustments and adaptations to new post-pandemic habits. Throughout 2020 and 2021 cycling has become a trend for a healthy lifestyle that people are interested in. With the rise of people cycling, sales of bicycles and their supporting equipment such as apparel have also increased. Seeing the trend of cycling and commuter bike riders who use bicycles as the main mode of transportation for daily mobilization, this becomes a potential for designing cargo pants for commuter bike riders with a sustainable design approach. Cargo pants are versatile pants that prioritize utility with various compartments that can fit various user items. Exploration of the features and systems in the design product is expected to meet the needs of commuter bike users and provide alternative products to users.

    Manufacturing development of pultruded composite panels

    Get PDF
    The weight savings potential, of graphite-epoxy composites for secondary and medium primary aircraft structures, was demonstrated. One of the greatest challenges facing the aircraft industry is to reduce the acquisition costs for composite structures to a level below that of metal structures. The pultrusion process, wherein reinforcing fibers, after being passed through a resin bath are drawn through a die to form and cure the desired cross-section, is an automated low cost manufacturing process for composite structures. The Lockheed Aeronautical Systems Company (LASC) Composites Development Center designed, characterizated materials for, fabricated and tested a stiffened cover concept compatible with the continuous pultrusion process. The procedures used and the results obtained are presented

    Rancang Bangun Alat Pelipat Pakaian Otomatis Menggunakan Sensor Shield Berbasis Arduino Uno

    Get PDF
    Teknologi saat ini sangat berkembang dengan munculya peralatan-peralatan canggih. Teknologi tersebut banyak digunakan untuk memudahkan orang untuk berkarya membuat alat yang dapat digunakan untuk membantu manusia, salah satunya adalah menciptakan alat melipat pakaian otomatis  yang dapat digunakan di rumah atau di perusahaan yang bergerak dibidang usaha laundry. Upaya ini dilakukan  untuk membantu pekerjaan manusia, dimana dirancang suatu alat canggih yang berfungsi untuk melipat pakaian secara otomatis yang sebelumnya dilakukan secara manual. Dalam Rancang bangun alat pelipat kain otomatis ini, beberapa komponen perangkat keras  yang digunakan adalah Power Supply, Saklar On/Off, Sensor Ultrasonik, Motor Servo, Buzzer, Sensor Shield dan Arduino Uno. Perangkat lunak (software) yang digunakan untuk menjalankan rancangan alat tersebut ialah Arduino IDE, dimana Arduino IDE ini dapat membuat, mengedit dan mengupload instruksi-instruki program  kedalam Arduino Uno. Bahasa pemrograman yang dipakai dalam membuat atau menjalankan program pelipat pakaian otomatis ini adalah menggunakan bahasa pemrograman C. Metode  penelitian yang digunakan adalah pendeketan kualitatif yaitu dengan Research Development (RD), yaitu penelitian yang bisa dipahami dengan cara melihat, mengamati atau mencari, sehingga rangkaian kegiatan yang dilakukan mendapatkan pemahaman yang lebih komprehensif dari suatu hal yang diteliti. Dengan adanya alat pelipat pakaian otomatis tersebut diharapkan dapat   membantu dalam hal melipat pakaian dengan rapih, menghemat tenaga dan waktu

    Folding Clothes Tool Using Arduino Uno Microcontroller And Gear Servo

    Get PDF
    Folding clothes is one of the homework that is often done for housewives, from a survey conducted on 200 housewives in Pekanbaru, the problem is that many housewives choose to fold family clothes by hand, this takes time and the energy to do the job. Based on these problems, the authors designed a microcontroller with a servo motor as a practical medium in folding the clothes applied to the clothes folding tool, where the author uses the Hardware Programming Methodology in order to carry out this research smoothly, the materials needed in this research are Arduino Uno, Gear. Servo, Power Supply, and software components. The result of this research is the creation of an automatic clothes folding device that is useful for simplifying household chores. From the test results, it can be concluded that this tool can fold clothes with a duration of 2 seconds
    corecore