1,342 research outputs found
Evaluation of machine-learning methods for ligand-based virtual screening
Machine-learning methods can be used for virtual screening by analysing the structural characteristics of molecules of known (in)activity, and we here discuss the use of kernel discrimination and naive Bayesian classifier (NBC) methods for this purpose. We report a kernel method that allows the processing of molecules represented by binary, integer and real-valued descriptors, and show that it is little different in screening performance from a previously described kernel that had been developed specifically for the analysis of binary fingerprint representations of molecular structure. We then evaluate the performance of an NBC when the training-set contains only a very few active molecules. In such cases, a simpler approach based on group fusion would appear to provide superior screening performance, especially when structurally heterogeneous datasets are to be processed
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Multimodal biometrics score level fusion using non-confidence information
Multimodal biometrics refers to automatic authentication methods that depend on multiple modalities of measurable physical characteristics. It alleviates most of the restrictions of single biometrics. To combine the multimodal biometrics scores, three different categories of fusion approaches including rule based, classification based and density based approaches are available. When choosing an approach, one has to consider not only the fusion performance, but also system requirements and other circumstances. In the context of verification, classification errors arise from samples in the overlapping region (or non- confidence region) between genuine users and impostors. In score space, a further separation of the samples outside the non-confidence region does not result in further verification improvements. Therefore, information contained in the non-confidence region might be useful for improving the fusion process. Up to this point, no attempts are reported in the literature that tries to enhance the fusion process using this additional information. In this work, the use of this information is explored in rule based and density based approaches mentioned above
An Evaluation of Score Level Fusion Approaches for Fingerprint and Finger-vein Biometrics
Biometric systems have to address many requirements, such as large population
coverage, demographic diversity, varied deployment environment, as well as
practical aspects like performance and spoofing attacks. Traditional unimodal
biometric systems do not fully meet the aforementioned requirements making them
vulnerable and susceptible to different types of attacks. In response to that,
modern biometric systems combine multiple biometric modalities at different
fusion levels. The fused score is decisive to classify an unknown user as a
genuine or impostor. In this paper, we evaluate combinations of score
normalization and fusion techniques using two modalities (fingerprint and
finger-vein) with the goal of identifying which one achieves better improvement
rate over traditional unimodal biometric systems. The individual scores
obtained from finger-veins and fingerprints are combined at score level using
three score normalization techniques (min-max, z-score, hyperbolic tangent) and
four score fusion approaches (minimum score, maximum score, simple sum, user
weighting). The experimental results proved that the combination of hyperbolic
tangent score normalization technique with the simple sum fusion approach
achieve the best improvement rate of 99.98%.Comment: 10 pages, 5 figures, 3 tables, conference, NISK 201
Strategies for exploiting independent cloud implementations of biometric experts in multibiometric scenarios
Cloud computing represents one of the fastest growing areas of technology and offers a new computing model for various applications and services. This model is particularly interesting for the area of biometric recognition, where scalability, processing power and storage requirements are becoming a bigger and bigger issue with each new generation of recognition technology. Next to the availability of computing resources, another important aspect of cloud computing with respect to biometrics is accessability. Since biometric cloud-services are easily accessible, it is possible to combine different existing implementations and design new multi-biometric services that next to almost unlimited resources also offer superior recognition performance and, consequently, ensure improved security to its client applications. Unfortunately, the literature on the best strategies of how to combine existing implementations of cloud-based biometric experts into a multi-biometric service is virtually non-existent. In this paper we try to close this gap and evaluate different strategies for combining existing biometric experts into a multi-biometric cloud-service. We analyze the (fusion) strategies from different perspectives such as performance gains, training complexity or resource consumption and present results and findings important to software developers and other researchers working in the areas of biometrics and cloud computing. The analysis is conducted based on two biometric cloud-services, which are also presented in the paper
Generic multimodal biometric fusion
Biometric systems utilize physiological or behavioral traits to automatically identify individuals. A unimodal biometric system utilizes only one source of biometric information and suffers from a variety of problems such as noisy data, intra-class variations, restricted degrees of freedom, non-universality, spoof attacks and unacceptable error rates. Multimodal biometrics refers to a system which utilizes multiple biometric information sources and can overcome some of the limitation of unimodal system. Biometric information can be combined at 4 different levels: (i) Raw data level; (ii) Feature level; (iii) Match-score level; and (iv) Decision level. Match score fusion and decision fusion have received significant attention due to convenient information representation and raw data fusion is extremely challenging due to large diversity of representation. Feature level fusion provides a good trade-off between fusion complexity and loss of information due to subsequent processing. This work presents generic feature information fusion techniques for fusion of most of the commonly used feature representation schemes. A novel concept of Local Distance Kernels is introduced to transform the available information into an arbitrary common distance space where they can be easily fused together. Also, a new dynamic learnable noise removal scheme based on thresholding is used to remove shot noise in the distance vectors. Finally we propose the use of AdaBoost and Support Vector Machines for learning the fusion rules to obtain highly reliable final matching scores from the transformed local distance vectors. The integration of the proposed methods leads to large performance improvement over match-score or decision level fusion
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