14 research outputs found

    A Review of the Teaching and Learning on Power Electronics Course

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    —In this review, we describe various kinds of problem and solution related teaching and learning on power electronics course all around the world. The method was used the study of literature on journal articles and proceedings published by reputable international organizations. Thirtynine papers were obtained using Boolean operators, according to the specified criteria. The results of the problems generally established that student learning motivation was low, teaching approaches that are still teacher-centered, the scope of the curriculum extends, and the physical limitations of laboratory equipment. The solutions offered are very diverse ranging from models, strategies, methods and learning techniques supported by information and communication technology

    23.2 The Poetic Eye

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    Rampike Vol. 23 / No. 2 (The Poetic Eye issue): Jaap Blonk, Barrie Tullet , Gustave Morin, Gregory Betts, Gary Barwin, Melody Sumner-Carnahan, W.M. Sutherland, Dennis Tourbin, Michael Winkler, Fernando Aguiar, Carol Stetser, Marilyn Rosenberg, Stan Rogal, Keith Garebian, Wendell Mayo, Andrew M. Niss, Lucas Crawford, Richard Kostelanetz, Antoni Miro, Amin Rehman, Lorenzo Menoud, LeRoy Gorman, Reed Altemus, Dennis Cooley, Mac MacArthur, Jürgen Olbrich, Nico Vassilakis, Elke Grundman, Anti-Oedipus, Aditya Bahl, Barrie Walsh, Derek Beaulieu, John M. Bennett, Joseph A. Brown & Terry Trowbridge, Vittore Baroni, Karl Kempton, Sergio Monteiro de Almeida, Serse Luigetti, Aaron Daigle, Gerry Shikatani, tENTATIVELY a cONVENIENCE, Stephanie Strange, John Nyman, Helen Hajnoczky, Ken Hunt, John Massey, Andrew Topel, rob mclennan & derek beaulieu & Kit Dobson, & bpNichol, Karl Jirgens, Fausto Bedoya. Front Cover Art: Jaap Blonk. Back Cover Art: Gustave Morin

    John D. and Catherine T. MacArthur Foundation - 2006 Annual Report

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    Contains president's essay, grant summaries, profiles of MacArthur Fellows Program award recipients, timeline of the year in review, financial statements, and list of officers and staff

    PROGRAMMED TRANSLATIONAL RECODING SIGNALS AS A THERAPEUTIC TARGET AGAINST ALPHAVIRUSES

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    While infection from communicable diseases has posed a longstanding threat to human health throughout history, the modern realities of population expansion, global travel, and climate change have facilitated the rapid emergence and worldwide distribution of RNA viruses at an unprecedented scale. Of particular concern are the alphaviruses, mosquito borne viruses from the Togaviridae family. These viruses were previously relegated to rare outbreaks in isolated forested regions but have dramatically spread across the globe in the past decade. One of these viruses, Venezuelan equine encephalitis virus (VEEV), is a noted bioterror threat due to its ability for aerosol transmission and successful weaponization during the Cold War. While no FDA approved drugs exist against alphaviruses, their reliance on programmed translational recoding mechanisms to regulate gene expression presents a potential vulnerability for therapeutic exploitation. Two instances of translational recoding have been identified but poorly characterized in the alphavirus genome. The first is a termination codon readthrough (TCR) event required for expression of the alphavirus replicase. The second is a programmed -1 ribosomal frameshift (-1 PRF) that produces a C-terminally extended variant of viroporin 6K. In this work, the cis-acting RNA elements that mitigate alphavirus recoding were functionally and structurally characterized. The predicted TCR and -1 PRF sequences were cloned into dual luciferase reporter vectors and their ability to promote efficient recoding was verified in several mammalian cell lines. Chemical probing assays elucidated the presence of highly structured stemloop elements downstream of the alphavirus recoding sites, which function as a kinetic trap for elongating ribosomes. Notably, mutations that abrogate efficient -1 PRF not only attenuated pathogenesis of VEEV in mice, but also provided protective immunity to subsequent wild-type challenge. These findings suggest a novel approach to the development of a safe and effective live attenuated vaccine strategy against VEEV, closely related alphaviruses, and potentially all viruses that rely on translational recoding mechanisms for optimal gene expression

    Mathematical analysis of deception.

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    Safeguarding Employee Privacy in U.S.-Based Small and Midsized Businesses

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    AbstractEmployee privacy is a contentious concern between employees and employers in the United States. Terminating oversurveilled employees may result in sustained claim costs for a company. Grounded in complexity theory and complexity leadership theory, the purpose of this qualitative multiple case study was to explore strategies small business leaders/agents use to safeguard employee privacy. The participants included three privacy practitioners: one consultant, and two small business leaders/agents of small businesses in the Mid-Atlantic U.S. region who had successfully safeguarded employee privacy. A thematic analysis using primary and secondary sources identified three principal themes: (a) environmental privacy, (b) autonomy privacy, and (c) personal information privacy. A key recommendation is for business leaders to design a human-centric employee privacy program with defensive and offensive strategies that balance autonomy with accountability. This study has implications for positive social change in that it may inform efficacious strategy to promote employee privacy that catalyze employee innovation and improve business performance, enabling organizations to sustain their contributions to benefit the citizens of their local community
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