Severity classification for idiopathic pulmonary fibrosis by using fuzzy logic

OBJECTIVE: To set out a severity classification for idiopathic pulmonary fibrosis (IPF) based on the interaction of pulmonary function parameters with high resolution computed tomography (CT) findings. INTRODUCTION: Despite the contribution of functional and radiological methods in the study of IPF, there are few classification proposals for the disease based on these examinations. METHODS: A cross-sectional study was carried out, in which 41 non-smoking patients with IPF were evaluated. The following high resolution CT findings were quantified using a semi-quantitative scoring system: reticular abnormality, honeycombing and ground-glass opacity. The functional variables were measured by spirometry, forced oscillation technique, helium dilution method, as well as the single-breath method of diffusing capacity of carbon monoxide. With the interaction between functional indexes and high resolution CT scores through fuzzy logic, a classification for IPF has been built. RESULTS: Out of 41 patients studied, 26 were male and 15 female, with a mean age of 70.8 years. Volume measurements were the variables which showed the best interaction with the disease extension on high resolution CT, while the forced vital capacity showed the lowest estimative errors in comparison to total lung capacity. A classification for IPF was suggested based on the 95% confidence interval of the forced vital capacity %: mild group (>92.7); moderately mild (76.9-92.6); moderate (64.3-76.8%); moderately severe (47.1-64.2); severe (24.3-47.0); and very severe (<24.3). CONCLUSION: Through fuzzy logic, an IPF classification was built based on forced vital capacity measurement with a simple practical application

THE ROLE OF ARTIFICIAL NEURAL NETWORKS IN DETECTION OF PULMONARY FUNCTIONAL ABNORMALITIES

Umjetna neuronska mreža je sustav temeljen na radu biološke neuronske mreže, drugim riječima, ona predstavlja oponašanje biološke neuronske mreže. Cilj ovog rada je usporediti svojstva dviju različitih verzija neuronski mrežnih ART algoritama kao što su neizravne ART i ARTFC metode korištene za klasifikaciju plućnih funkcija, otkrivanje restriktivnih, opstruktivnih i normalinih uzoraka disajnih abnormalnosti putem svake neuronske mreže s podacima prikupljenim spirometrijom. Spirometrijski podaci su prikupljeni na 150 pacijenata standardnim postupkom prikupljanja, gdje se 100 ispitanika koristi za obuku i 50 za testiranje, respektivno. Rezultati su pokazali da standardi neizravni ART algoritam raste brže od ARTFC, koji uspješno rješava problem kategorizacije proliferacija.An artificial neural network is a system based on the operation of biological neural networks, in other words, it is an emulation of the biological neural system. The objective of this study is to compare the performance of two different versions of neural network ART algorithms such as Fuzzy ART vs. ARTFC methods used for classification of pulmonary function, detecting restrictive, obstructive and normal patterns of respiratory abnormalities by means of each of the neural networks, as well as the data gathered from spirometry. The spirometry data were obtained from 150 patients by standard acquisition protocol, 100 subjects used for training and 50 subjects for testing, respectively. The results showed that the standard Fuzzy ART grows faster than ARTFC, which successfully solves the category proliferation problem

Aerospace Medicine and Biology: A continuing bibliography, supplement 191

A bibliographical list of 182 reports, articles, and other documents introduced into the NASA scientific and technical information system in February 1979 is presented

Fuzzy logic: A “simple” solution for complexities in neurosciences?

Background: Fuzzy logic is a multi-valued logic which is similar to human thinking and interpretation. It has the potential of combining human heuristics into computer-assisted decision making, which is applicable to individual patients as it takes into account all the factors and complexities of individuals. Fuzzy logic has been applied in all disciplines of medicine in some form and recently its applicability in neurosciences has also gained momentum.Methods: This review focuses on the use of this concept in various branches of neurosciences including basic neuroscience, neurology, neurosurgery, psychiatry and psychology.Results: The applicability of fuzzy logic is not limited to research related to neuroanatomy, imaging nerve fibers and understanding neurophysiology, but it is also a sensitive and specific tool for interpretation of EEGs, EMGs and MRIs and an effective controller device in intensive care units. It has been used for risk stratification of stroke, diagnosis of different psychiatric illnesses and even planning neurosurgical procedures.Conclusions: In the future, fuzzy logic has the potential of becoming the basis of all clinical decision making and our understanding of neurosciences

Thrombophilia screening: An artificial neural network approach

Thrombotic disorders have severe consequences for the patients and for the society in general, being one of the main causes of death. These facts reveal that it is extremely important to be preventive; being aware of how probable is to have that kind of syndrome. Indeed, this work will focus on the development of a decision support system that will cater for an individual risk evaluation with respect to the surge of thrombotic complaints. The Knowledge Representation and Reasoning procedures used will be based on an extension to the Logic Programming language, allowing the handling of incomplete and/or default data. The computational framework in place will be centered on Artificial Neural Networks.This work is funded by National Funds through the FCT – Fundação para a Ciência e a Tecnologia (Portuguese Foundation for Science and Technology) within projects PEst-OE/EEI/UI0752/2014 and PEst-OE/QUI/UI0619/2012

Symptoms-Based Fuzzy-Logic Approach for COVID-19 Diagnosis

The coronavirus (COVID-19) pandemic has caused severe adverse effects on the human life and the global economy affecting all communities and individuals due to its rapid spreading, increase in the number of affected cases and creating severe health issues and death cases worldwide. Since no particular treatment has been acknowledged so far for this disease, prompt detection of COVID-19 is essential to control and halt its chain. In this paper, we introduce an intelligent fuzzy inference system for the primary diagnosis of COVID-19. The system infers the likelihood level of COVID-19 infection based on the symptoms that appear on the patient. This proposed inference system can assist physicians in identifying the disease and help individuals to perform self-diagnosis on their own cases

Expert System with an Embedded Imaging Module for Diagnosing Lung Diseases

Lung diseases are one of the major causes of suffering and death in the world. Improved survival rate could be obtained if the diseases can be detected at its early stage. Specialist doctors with the expertise and experience to interpret medical images and diagnose complex lung diseases are scarce. In this work, a rule-based expert system with an embedded imaging module is developed to assist the general physicians in hospitals and clinics to diagnose lung diseases whenever the services of specialist doctors are not available. The rule-based expert system contains a large knowledge base of data from various categories such as patient's personal and medical history, clinical symptoms, clinical test results and radiological information. An imaging module is integrated into the expert system for the enhancement of chest X-Ray images. The goal of this module is to enhance the chest X-Ray images so that it can provide details similar to more expensive methods such as MRl and CT scan. A new algorithm which is a modified morphological grayscale top hat transform is introduced to increase the visibility of lung nodules in chest X-Rays. Fuzzy inference technique is used to predict the probability of malignancy of the nodules. The output generated by the expert system was compared with the diagnosis made by the specialist doctors. The system is able to produce results\ud which are similar to the diagnosis made by the doctors and is acceptable by clinical standards

Analysis of Respiratory Sounds: State of the Art

Objective This paper describes state of the art, scientific publications and ongoing research related to the methods of analysis of respiratory sounds. Methods and material Review of the current medical and technological literature using Pubmed and personal experience. Results The study includes a description of the various techniques that are being used to collect auscultation sounds, a physical description of known pathologic sounds for which automatic detection tools were developed. Modern tools are based on artificial intelligence and on technics such as artificial neural networks, fuzzy systems, and genetic algorithms… Conclusion The next step will consist in finding new markers so as to increase the efficiency of decision aid algorithms and tools