Artificial neural network-statistical approach for PET volume analysis and classification

Copyright © 2012 The Authors. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.This article has been made available through the Brunel Open Access Publishing Fund.The increasing number of imaging studies and the prevailing application of positron emission tomography (PET) in clinical oncology have led to a real need for efficient PET volume handling and the development of new volume analysis approaches to aid the clinicians in the clinical diagnosis, planning of treatment, and assessment of response to therapy. A novel automated system for oncological PET volume analysis is proposed in this work. The proposed intelligent system deploys two types of artificial neural networks (ANNs) for classifying PET volumes. The first methodology is a competitive neural network (CNN), whereas the second one is based on learning vector quantisation neural network (LVQNN). Furthermore, Bayesian information criterion (BIC) is used in this system to assess the optimal number of classes for each PET data set and assist the ANN blocks to achieve accurate analysis by providing the best number of classes. The system evaluation was carried out using experimental phantom studies (NEMA IEC image quality body phantom), simulated PET studies using the Zubal phantom, and clinical studies representative of nonsmall cell lung cancer and pharyngolaryngeal squamous cell carcinoma. The proposed analysis methodology of clinical oncological PET data has shown promising results and can successfully classify and quantify malignant lesions.This study was supported by the Swiss National Science Foundation under Grant SNSF 31003A-125246, Geneva Cancer League, and the Indo Swiss Joint Research Programme ISJRP 138866. This article is made available through the Brunel Open Access Publishing Fund

Performance characterization of clustering algorithms for colour image segmentation

This paper details the implementation of three traditional clustering techniques (K-Means clustering, Fuzzy C-Means clustering and Adaptive K-Means clustering) that are applied to extract the colour information that is used in the image segmentation process. The aim of this paper is to evaluate the performance of the analysed colour clustering techniques for the extraction of optimal features from colour spaces and investigate which method returns the most consistent results when applied on a large suite of mosaic images

Markov mezők a képmodellezésben, alkalmazásuk az automatikus képszegmentálás területén = Markovian Image Models: Applications in Unsupervised Image Segmentation

1) Kifejlesztettünk egy olyan szín és textúra alapú szegmentáló MRF algoritmust, amely alkalmas egy kép automatikus szegmentálását elvégezni. Az eredményeinket az Image and Vision Computing folyóiratban publikáltuk. 2) Kifejlesztettünk egy Reversible Jump Markov Chain Monte Carlo technikán alapuló automatikus képszegmentáló eljárást, melyet sikeresen alkalmaztunk színes képek teljesen automatikus szegmentálására. Az eredményeinket a BMVC 2004 konferencián és az Image and Vision Computing folyóiratban publikáltuk. 3) A modell többrétegű továbbfejlesztését alkalmaztuk video objektumok szín és mozgás alapú szegmentálására, melynek eredményeit a HACIPPR 2005 illetve az ACCV 2006 nemzetközi konferenciákon publikáltuk. Szintén ehhez az alapproblémához kapcsolódik Horváth Péter hallgatómmal az optic flow szamításával illetve szín, textúra és mozgás alapú GVF aktív kontúrral kapcsoltos munkáink. TDK dolgozata első helyezést ért el a 2004-es helyi versenyen, az eredményeinket pedig a KEPAF 2004 konferencián publikáltuk. 4) Horváth Péter PhD hallgatómmal illetve az franciaországi INRIA Ariana csoportjával, kidolgoztunk egy olyan képszegmentáló eljárást, amely a szegmentálandó objektum alakját is figyelembe veszi. Az eredményeinket az ICPR 2006 illetve az ICCVGIP 2006 konferencián foglaltuk össze. A modell előzményeként kidolgoztunk továbbá egy alakzat-momemntumokon alapuló aktív kontúr modellt, amelyet a HACIPPR 2005 konferencián publikáltunk. | 1) We have proposed a monogrid MRF model which is able to combine color and texture features in order to improve the quality of segmentation results. We have also solved the estimation of model parameters. This work has been published in the Image and Vision Computing journal. 2) We have proposed an RJMCMC sampling method which is able to identify multi-dimensional Gaussian mixtures. Using this technique, we have developed a fully automatic color image segmentation algorithm. Our results have been published at BMVC 2004 international conference and in the Image and Vision Computing journal. 3) A new multilayer MRF model has been proposed which is able to segment an image based on multiple cues (such as color, texture, or motion). This work has been published at HACIPPR 2005 and ACCV 2006 international conferences. The work on optic flow computation and color-, texture-, and motion-based GVF active contours doen with my student, Mr. Peter Horvath, won a first price at the local Student Research Competition in 2004. Results have been presented at KEPAF 2004 conference. 4) A new shape prior, called 'gas of circles' has been introduced using active contour models. This work is done in collaboration with the Ariana group of INRIA, France and my PhD student, Mr. Peter Horvath. Results are published at the ICPR 2006 and ICCVGIP 2006 conferences. A preliminary study on active contour models using shape-moments has also been done, these results are published at HACIPPR 2005

Semi-supervised cross-entropy clustering with information bottleneck constraint

In this paper, we propose a semi-supervised clustering method, CEC-IB, that models data with a set of Gaussian distributions and that retrieves clusters based on a partial labeling provided by the user (partition-level side information). By combining the ideas from cross-entropy clustering (CEC) with those from the information bottleneck method (IB), our method trades between three conflicting goals: the accuracy with which the data set is modeled, the simplicity of the model, and the consistency of the clustering with side information. Experiments demonstrate that CEC-IB has a performance comparable to Gaussian mixture models (GMM) in a classical semi-supervised scenario, but is faster, more robust to noisy labels, automatically determines the optimal number of clusters, and performs well when not all classes are present in the side information. Moreover, in contrast to other semi-supervised models, it can be successfully applied in discovering natural subgroups if the partition-level side information is derived from the top levels of a hierarchical clustering