The safe administration of medication within the electromagnetic scenarios of the Internet of Things (IoT): looking towards the future

This paper has focused on analyzing the impact of Information and Communication Technologies (ICTs) to prevent or reduce errors during therapeutic drug administration. The methodology used has included scientific literature and marketed appliances reviews and laboratory tests on radiant devices. The role of the patient has been analyzed, both in terms of compliance with the prescribed treatments and user of technical solutions designed for administering medication. In addition, it has taken into account, how a future characterized by multiple technologies designed to support our daily routines, including health care, might affect the current model of relationship between health professionals and patients. Particular attention has been given to safety risks of ICTs in environments characterized by concurrent electromagnetic emissions operating at different frequencies. Implications and new scenarios from Internet of Things or IoT, have been considered, in light of the approach taken jointly by the European Commission and the European Technology Platform on Intelligent Systems Integration – EPoSS, in their 2008 report Internet of Things in 2020: a roadmap for the future, and how the concept has evolved since then.Chapter 1. Adverse drug events. Chapter 2. ICTs in everyday life and healthcare. Chapter 3. the challenge of electromagnetic safety. Chapter 4. ICTs in health care and in the prevention of medication errors: IoT. Chapter 5. A more effective and safer alternative approach. Chapter 6. Technological proposal 7. Conclusions.N

A Systematic Framework for Radio Frequency Identification (RFID) Hazard Mitigation in the Blood Transfusion Supply Chain from Donation to Distribution

The RFID Consortium is developing what will be the first FDA-approved use of radio frequency identification (RFID) technology to identify, track, manage, and monitor blood throughout the entire blood transfusion supply chain. The iTraceTM is an innovative technological system designed to optimize the procedures currently employed when tracing blood from the donor to the recipient. With all novel technologies it is essential to consider not only the advantages, but also the potential harms that may come about from using the system. The deployment of the iTraceTM consists of two phases: 1) Phase One - application of the iTraceTM from the donor to blood center distribution, and 2) Phase Two - application of the iTraceTM from blood center distribution to transfusion. This dissertation seeks to identify the possible hazards that may occur when utilizing the iTraceTM during Phase One, and to assess the mitigation and correction processes to combat these hazards. A thorough examination of verification and validation tests, as well as of the system design, requirements, and standard operating procedures was performed to qualify and quantify each hazard into specific categories of severity and likelihood. A traceability matrix was also established to link each hazard with its associated tests and/or features. Furthermore, a series of analyses were conducted to determine whether the benefits of implementing the iTraceTM outweighed the risks and whether the mitigation and correction strategies of the hazards were effective. Ultimately, this dissertation serves as a usable, generalizable framework for the management of RFID-related hazards in the blood transfusion supply chain from donor to blood center distribution

Radio Frequency Identification (RFID) in health care: where are we? A scoping review

Purpose (RFID) is a technology that uses radio waves for data collection and transfer, so data is captured efficiently, automatically and in real time without human intervention. This technology, alone or in addition to other technologies has been considered as a possible solution to reduce problems that endanger public health or to improve its management. This scoping review aims to provide readers with an up-to-date picture of the use of this technology in health care settings. Methods This scoping review examines the state of RFID technology in the healthcare area for the period 2017-2022, specifically addressing RFID versatility and investigating how this technology can contribute to radically change the management of public health. The guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) have been followed. Literature reviews or surveys were excluded. Only articles describing technologies implemented on a real environment or on prototypes were included. Results The search returned 366 results. After screening, based on title and abstract, 58 articles were considered suitable for this work. 11 articles were reviewed because they met the qualifying requirements. The study of the selected articles highlighted six matters that can be profitably impacted by this technology Conclusion The selected papers show that this technology can improve patient safety by reducing medical errors, that can occur within operating rooms. It can also be the solution to overcome the problem of the black market in counterfeiting drugs, or as a prevention tool. Further research is needed, especially on data management, security, and privacy, given the sensitive nature of medical information

Radio Frequency Identification (RFID) in health care: where are we? A scoping review

Purpose: (RFID) is a technology that uses radio waves for data collection and transfer, so data is captured efficiently, automatically and in real time without human intervention. This technology, alone or in addition to other technologies has been considered as a possible solution to reduce problems that endanger public health or to improve its management. This scoping review aims to provide readers with an up-to-date picture of the use of this technology in health care settings. Methods: This scoping review examines the state of RFID technology in the healthcare area for the period 2017-2022, specifically addressing RFID versatility and investigating how this technology can contribute to radically change the management of public health. The guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) have been followed. Literature reviews or surveys were excluded. Only articles describing technologies implemented on a real environment or on prototypes were included. Results: The search returned 366 results. After screening, based on title and abstract, 58 articles were considered suitable for this work. 11 articles were reviewed because they met the qualifying requirements. The study of the selected articles highlighted six matters that can be profitably impacted by this technology Conclusion: The selected papers show that this technology can improve patient safety by reducing medical errors, that can occur within operating rooms. It can also be the solution to overcome the problem of the black market in counterfeiting drugs, or as a prevention tool. Further research is needed, especially on data management, security, and privacy, given the sensitive nature of medical information. Graphical Abstract: [Figure not available: see fulltext.

Enabling Hardware Green Internet of Things: A review of Substantial Issues

Between now and the near future, the Internet of Things (IoT) will redesign the socio-ecological morphology of the human terrain. The IoT ecosystem deploys diverse sensor platforms connecting millions of heterogeneous objects through the Internet. Irrespective of sensor functionality, most sensors are low energy consumption devices and are designed to transmit sporadically or continuously. However, when we consider the millions of connected sensors powering various user applications, their energy efficiency (EE) becomes a critical issue. Therefore, the importance of EE in IoT technology, as well as the development of EE solutions for sustainable IoT technology, cannot be overemphasised. Propelled by this need, EE proposals are expected to address the EE issues in the IoT context. Consequently, many developments continue to emerge, and the need to highlight them to provide clear insights to researchers on eco-sustainable and green IoT technologies becomes a crucial task. To pursue a clear vision of green IoT, this study aims to present the current state-of-the art insights into energy saving practices and strategies on green IoT. The major contribution of this study includes reviews and discussions of substantial issues in the enabling of hardware green IoT, such as green machine to machine, green wireless sensor networks, green radio frequency identification, green microcontroller units, integrated circuits and processors. This review will contribute significantly towards the future implementation of green and eco-sustainable IoT

Integrating the Supply Chain with RFID: A Technical and Business Analysis

This paper presents an in-depth analysis of the technical and business implications of adopting Radio Frequency Identification (RFID) in organizational settings. The year 2004 marked a significant shift toward adopting RFID because of mandates by large retailers and government organizations. The use of RFID technology is expected to increase rapidly in the next few years. At present, however, initial barriers against widespread adoption include standards, interoperability, costs, forward compatibility, and lack of familiarity. This paper describes basic components of an RFID system including tags, readers, and antennas and how they work together using an integrated supply chain model. Our analysis suggests that business needs to overcome human resource scarcity, security, legal and financial challenges and make informed decision regarding standards and process reengineering. The technology is not fully mature and suffers from issues of attenuation and interference. A laboratory experiment conducted by the authors\u27 shows that the middleware is not yet at a plug-and-play stage, which means that initial adopters need to spend considerable effort to integrate RFID into their existing business processes. Appendices contain a glossary of common RFID terms, a list of RFID vendors and detailed findings of the laboratory experiment. NOTE: BECAUSE OF THE ILLUSTRATIONS USED, THIS ARTICLE IS LONG; APPROXIMATELY 850KB IN BOTH JOURNAL AND ARTICLE VERSIO

Towards early hemolysis detection: a smartphone based approach

Os especialistas em diagnóstico in vitro (IVDs) têm confiado maioritariamente na inspeção visual (ótica) manual e, em segundo lugar, em sensores óticos ou câmaras embutidas ou dispositivos médicos incorporados que suportam o exame da qualidade da amostra na fase pré-analítica. Com o aumento dos volumes de amostras para serem processadas e dos respetivos dados complexos gerados por esse processamento, aquelas técnicas tornaram-se cada vez mais difíceis de utilizar, ou os respetivos resultados não ficam imediatamente disponíveis. Para superar as complexidades impostas por tais técnicas tradicionais, o aumento do uso de dispositivos móveis e algoritmos de processamento de imagem no setor de saúde abriu caminho para a constituição de novos casos de uso baseados em análises móveis de amostras, pois fornecem uma interação simples e intuitiva com objetos gráficos familiares que são mostrados no ecrã dos smartphones. As interfaces gráficas e as técnicas de interação suportadas por dispositivos móveis podem pois proporcionar ao especialista em IVD uma série de vantagens e valor agregado devido à maior familiaridade com estes dispositivos e à grande acessibilidade que evidenciam atualmente, tendo o potencial de facilitar as análises de amostras. No entanto, o uso sistemático de dispositivos móveis no setor da saúde encontra-se ainda numa fase muito incipiente, em particular na área de IVD. Nesta tese, propõe-se conceber e discutir a arquitetura, a conceção e a implementação de um protótipo de uma aplicação móvel para smartphone (designada por "HemoDetect") que implementa um conjunto sugerido de algoritmos, interfaces e técnicas de interação que foram desenvolvidos com o objetivo de contribuir para a compreensão de técnicas mais eficientes para ajudar a detetar a hemólise, um processo que designa a rotura de glóbulos vermelhos (eritrócitos) e libertação do respetivo conteúdo (citoplasma) para o fluído circundante (por exemplo, plasma sanguíneo), complementando-as com estatísticas e medições de laboratório, mostrando a utilização de um protótipo durante experiências, permitindo assim chegar-se a um conceito viável que permita apoiar eficazmente a deteção precoce de hemólise.In Vitro Diagnostics (IVDs) specialists have been firstly relying on manual visual (optical) inspection and, secondly, on optical sensors or cameras embedded or built-in medical devices which support the examination of sample quality in pre-analytical phase. With increasing sample processing volumes and their generated complex data, these techniques have become increasingly difficult or results are not readily available. In order to overcome the complexities posed by these traditional techniques, the increased usage of mobile devices and algorithms in the healthcare industry paves the way into shaping new use cases and discovery of mobile analysis of samples, as they provide a user-friendly and familiar interaction with objects displayed on their screens. The interfaces and interaction techniques rendered by mobile devices, bring, to the IVD specialist, a number of advantages and added value due to increased familiarity with the devices or their accessibility, which is made easier. However, they are at the beginning of their journey in the healthcare industry, in particular in the IVD and point-of-care areas. In this thesis, the proposal is to discover and discuss the architecture, design and implementation of a smartphone prototype app (called “HemoDetect”) with its algorithms, interfaces and interaction techniques which was developed to help detect hemolysis which represents the rupture of red blood cells (erythrocytes) and release of their contents (cytoplasm) into surrounding fluid (e.g. blood plasma), and complementing it with from-the-lab statistics and measurements showing its utilization during experiments, which ultimately may be a feasible concept that could support early hemolysis detection.Les spécialistes du diagnostic in vitro (DIV) se sont d'abord appuyés sur l'inspection visuelle (optique) manuelle et, ensuite, sur des capteurs optiques ou des caméras intégrées ou intégrées à des dispositifs médicaux qui facilitent l'examen de la qualité des échantillons en phase pré-analytique. Avec l'augmentation des volumes de traitement des échantillons et des données complexes générées, ces techniques sont devenues de plus en plus difficiles ou les résultats ne sont pas facilement disponibles. Afin de surmonter les complexités posées par ces techniques traditionnelles, l'utilisation croissante des appareils mobiles et des algorithmes dans le secteur de la santé ouvre la voie à la définition de nouveaux cas d'utilisation et à la découverte d'analyses d'échantillons mobiles, car ils fournissent une interaction conviviale et familière. avec des objets affichés sur leurs écrans. Les interfaces et les techniques d'interaction rendues par les appareils mobiles apportent au spécialiste des dispositifs de DIV un certain nombre d'avantages et de valeur ajoutée en raison d'une familiarisation accrue avec les appareils ou de leur accessibilité, ce qui est facilité. Cependant, ils sont au début de leur parcours dans le secteur de la santé, en particulier dans le domains des DIV et point-of-care. Dans cette thèse, la proposition est de découvrir et de discuter de l’architecture, de la conception et de la mise en oeuvre d’une application pour smartphone (appelée «HemoDetect») avec ses algorithmes, interfaces et techniques d’interaction, qui a été développée pour aider à détecter l’hémolyse qui représente une rupture des globules rouges (érythrocytes) et la libération de leur contenu (cytoplasme) dans le liquide environnant (par exemple, le plasma sanguin), en le complétant par des statistiques de laboratoire et des mesures montrant son utilisation au cours des expériences, ce qui pourrait finalement être un concept réalisable qui pourrait permettre une détection précoce de l'hémolyse

INVESTIGATING PRESENT AND FUTURE INTERACTIONS BETWEEN RADIO FREQUENCY IDENTIFICATION, ADDITIVE MANUFACTURING AND SUPPLY CHAIN MANAGEMENT

A screening experiment was paired with research observing the past, present and futures of additive manufacturing (a.k.a. rapid prototyping, 3D printing), radio frequency identification, and supply chain management. The experiment tested different properties of objects created with a desktop fused deposition modelling printer to observe if any single factors or interactions affected the read range of embedded passive UHF RFID inlay. The combination of material and infill percentage had a statistically significant effect on read range, however the analysis is weak since the data could not justify the normality assumption of ANOVA. Furthermore, the size of the effect was small enough to deny any practical difference. From the experiment and research, several presently capable interactions between AM and RFID were commented on. Future interactions between AM, RFID and SCM were also discussed, and a common relationship to physical objects was drawn

Characterization of Silicon Phosphorus Alloy for Device Applications

A new material of highly-phosphorus doped silicon for device applications was characterized and analyzed for new material properties. Devices such as NMOS transistors and other CMOS compatible devices may benefit from new materials that reduce external resistances and increase drive currents. Material characterization requires numerous techniques and technologies to determine electrical, optical, and physical characteristics. For this work, Hall measurement, X-ray Diffraction, Raman Spectroscopy, Photoluminescence Characterization, and Spectroscopic Ellipsometry were used to better understand this new material. The results may lead to new models for silicon phosphorus alloys