4,209 research outputs found
Neurophysiological Assessment of Affective Experience
In the field of Affective Computing the affective experience (AX) of the user during the interaction with computers is of great interest. The automatic recognition of the affective state, or emotion, of the user is one of the big challenges. In this proposal I focus on the affect recognition via physiological and neurophysiological signals. Long‐standing evidence from psychophysiological research and more recently from research in affective neuroscience suggests that both, body and brain physiology, are able to indicate the current affective state of a subject. However, regarding the classification of AX several questions are still unanswered. The principal possibility of AX classification was repeatedly shown, but its generalisation over different task contexts, elicitating stimuli modalities, subjects or time is seldom addressed. In this proposal I will discuss a possible agenda for the further exploration of physiological and neurophysiological correlates of AX over different elicitation modalities and task contexts
Leak localization in water distribution networks using a mixed model-based/data-driven approach
“The final publication is available at Springer via http://dx.doi.org/10.1016/j.conengprac.2016.07.006”This paper proposes a new method for leak localization in water distribution networks (WDNs). In a first stage, residuals are obtained by comparing pressure measurements with the estimations provided by a WDN model. In a second stage, a classifier is applied to the residuals with the aim of determining the leak location. The classifier is trained with data generated by simulation of the WDN under different leak scenarios and uncertainty conditions. The proposed method is tested both by using synthetic and experimental data with real WDNs of different sizes. The comparison with the current existing approaches shows a performance improvement.Peer ReviewedPostprint (author's final draft
Cloud cover determination in polar regions from satellite imagery
A definition is undertaken of the spectral and spatial characteristics of clouds and surface conditions in the polar regions, and to the creation of calibrated, geometrically correct data sets suitable for quantitative analysis. Ways are explored in which this information can be applied to cloud classifications as new methods or as extensions to existing classification schemes. A methodology is developed that uses automated techniques to merge Advanced Very High Resolution Radiometer (AVHRR) and Scanning Multichannel Microwave Radiometer (SMMR) data, and to apply first-order calibration and zenith angle corrections to the AVHRR imagery. Cloud cover and surface types are manually interpreted, and manual methods are used to define relatively pure training areas to describe the textural and multispectral characteristics of clouds over several surface conditions. The effects of viewing angle and bidirectional reflectance differences are studied for several classes, and the effectiveness of some key components of existing classification schemes is tested
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DNA methylation-based classification of central nervous system tumours.
Accurate pathological diagnosis is crucial for optimal management of patients with cancer. For the approximately 100 known tumour types of the central nervous system, standardization of the diagnostic process has been shown to be particularly challenging-with substantial inter-observer variability in the histopathological diagnosis of many tumour types. Here we present a comprehensive approach for the DNA methylation-based classification of central nervous system tumours across all entities and age groups, and demonstrate its application in a routine diagnostic setting. We show that the availability of this method may have a substantial impact on diagnostic precision compared to standard methods, resulting in a change of diagnosis in up to 12% of prospective cases. For broader accessibility, we have designed a free online classifier tool, the use of which does not require any additional onsite data processing. Our results provide a blueprint for the generation of machine-learning-based tumour classifiers across other cancer entities, with the potential to fundamentally transform tumour pathology
Predicting Native Language from Gaze
A fundamental question in language learning concerns the role of a speaker's
first language in second language acquisition. We present a novel methodology
for studying this question: analysis of eye-movement patterns in second
language reading of free-form text. Using this methodology, we demonstrate for
the first time that the native language of English learners can be predicted
from their gaze fixations when reading English. We provide analysis of
classifier uncertainty and learned features, which indicates that differences
in English reading are likely to be rooted in linguistic divergences across
native languages. The presented framework complements production studies and
offers new ground for advancing research on multilingualism.Comment: ACL 201
Quantitative Intensity Harmonization of Dopamine Transporter SPECT Images Using Gamma Mixture Models
PURPOSE:
Differences in site, device, and/or settings may cause large variations in the intensity profile of dopamine transporter (DAT) single-photon emission computed tomography (SPECT) images. However, the current standard to evaluate these images, the striatal binding ratio (SBR), does not efficiently account for this heterogeneity and the assessment can be unequivalent across distinct acquisition pipelines. In this work, we present a voxel-based automated approach to intensity normalize such type of data that improves on cross-session interpretation.
PROCEDURES:
The normalization method consists of a reparametrization of the voxel values based on the cumulative density function (CDF) of a Gamma distribution modeling the specific region intensity. The harmonization ability was tested in 1342 SPECT images from the PPMI repository, acquired with 7 distinct gamma camera models and at 24 different sites. We compared the striatal quantification across distinct cameras for raw intensities, SBR values, and after applying the Gamma CDF (GDCF) harmonization. As a proof-of-concept, we evaluated the impact of GCDF normalization in a classification task between controls and Parkinson disease patients.
RESULTS:
Raw striatal intensities and SBR values presented significant differences across distinct camera models. We demonstrate that GCDF normalization efficiently alleviated these differences in striatal quantification and with values constrained to a fixed interval [0, 1]. Also, our method allowed a fully automated image assessment that provided maximal classification ability, given by an area under the curve (AUC) of AUC = 0.94 when used mean regional variables and AUC = 0.98 when used voxel-based variables.
CONCLUSION:
The GCDF normalization method is useful to standardize the intensity of DAT SPECT images in an automated fashion and enables the development of unbiased algorithms using multicenter datasets. This method may constitute a key pre-processing step in the analysis of this type of images.Instituto de Salud Carlos III FI14/00497 MV15/00034Fondo Europeo de Desarrollo Regional FI14/00497 MV15/00034ISCIII-FEDER PI16/01575Wellcome Trust UK Strategic Award 098369/Z/12/ZNetherland Organization for Scientific Research NWO-Vidi 864-12-00
Beyond Probability Partitions: Calibrating Neural Networks with Semantic Aware Grouping
Research has shown that deep networks tend to be overly optimistic about
their predictions, leading to an underestimation of prediction errors. Due to
the limited nature of data, existing studies have proposed various methods
based on model prediction probabilities to bin the data and evaluate
calibration error. We propose a more generalized definition of calibration
error called Partitioned Calibration Error (PCE), revealing that the key
difference among these calibration error metrics lies in how the data space is
partitioned. We put forth an intuitive proposition that an accurate model
should be calibrated across any partition, suggesting that the input space
partitioning can extend beyond just the partitioning of prediction
probabilities, and include partitions directly related to the input. Through
semantic-related partitioning functions, we demonstrate that the relationship
between model accuracy and calibration lies in the granularity of the
partitioning function. This highlights the importance of partitioning criteria
for training a calibrated and accurate model. To validate the aforementioned
analysis, we propose a method that involves jointly learning a semantic aware
grouping function based on deep model features and logits to partition the data
space into subsets. Subsequently, a separate calibration function is learned
for each subset. Experimental results demonstrate that our approach achieves
significant performance improvements across multiple datasets and network
architectures, thus highlighting the importance of the partitioning function
for calibration
Developing a discrimination rule between breast cancer patients and controls using proteomics mass spectrometric data: A three-step approach
To discriminate between breast cancer patients and controls, we used a three-step approach to obtain our decision rule. First, we ranked the mass/charge values using random forests, because it generates importance indices that take possible interactions into account. We observed that the top ranked variables consisted of highly correlated contiguous mass/charge values, which were grouped in the second step into new variables. Finally, these newly created variables were used as predictors to find a suitable discrimination rule. In this last step, we compared three different methods, namely Classification and Regression Tree ( CART), logistic regression and penalized logistic regression. Logistic regression and penalized logistic regression performed equally well and both had a higher classification accuracy than CART. The model obtained with penalized logistic regression was chosen as we hypothesized that this model would provide a better classification accuracy in the validation set. The solution had a good performance on the training set with a classification accuracy of 86.3%, and a sensitivity and specificity of 86.8% and 85.7%, respectively
--PhotoZ: Photometric Redshifts by Inverting the Tolman Surface Brightness Test
Surface brightness is a fundamental observational parameter of galaxies. We
show, for the first time in detail, how it can be used to obtain photometric
redshifts for galaxies, the -PhotoZ method.
We demonstrate that the Tolman surface brightness relation, , is a powerful tool for determining galaxy redshifts from
photometric data.
We develop a model using and a color percentile (ranking) measure to
demonstrate the -PhotoZ method. We apply our method to a set of galaxies
from the SHELS survey, and demonstrate that the photometric redshift accuracy
achieved using the surface brightness method alone is comparable with the best
color-based methods.
We show that the -PhotoZ method is very effective in determining the
redshift for red galaxies using only two photometric bands. We discuss the
properties of the small, skewed, non-gaussian component of the error
distribution.
We calibrate from the SDSS to redshift, and tabulate the
result, providing a simple, but accurate look up table to estimate the redshift
of distant red galaxies.Comment: Accepted for publication in the Astronomical Journa
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