10,042 research outputs found
Design and Development of a Class EF2 Inverter and Rectifier for Multi-megahertz Wireless Power Transfer Systems
This paper presents the design and implementation of a Class EF2 inverter and Class EF2 rectifier for two -W wireless power transfer (WPT) systems, one operating at 6.78 MHz and the other at 27.12 MHz. It will be shown that the Class EF2 circuits can be designed to have beneficial features for WPT applications such as reduced second-harmonic component and lower total harmonic distortion, higher power-output capability, reduction in magnetic core requirements and operation at higher frequencies in rectification compared to other circuit topologies. A model will first be presented to analyze the circuits and to derive values of its components to achieve optimum switching operation. Additional analysis regarding harmonic content, magnetic core requirements and open-circuit protection will also be performed. The design and implementation process of the two Class-EF2-based WPT systems will be discussed and compared to an equivalent Class-E-based WPT system. Experimental results will be provided to confirm validity of the analysis. A dc-dc efficiency of 75% was achieved with Class-EF2-based systems
Colocalization of oxytocin and phosphorylated form of elongation factor 2 in the rat hypothalamus
Oxytocin (OT) is one of the neuropituitary hormones and is synthesized in the neurons of the paraventricular nucleus (PVN) and supraoptic nucleus (SON). Previous studies have shown that the mRNAs encoding OT are delivered from the soma to both dendrites and axons of the neurons in the PVN and SON. However, it has not been elucidated whether a translational regulation mechanism to enable local synthesis of the hormone exists in the axons of the neurons of PVN and SON. Elongation factor 2 (EF2) is essential for polypeptide synthesis during protein translation. Moreover, phosphorylation of EF2 by EF2 kinase enhances the translation of certain mRNA species. In the present study, in order to shed light on the mechanisms involved in the translational regulation of OT synthesis, we investigated the localization of phosphorylated EF2. Phospho-EF2 was localized in the soma of the neurons in PVN and SON, and in the swellings of the median eminence where axonal tracts of the neurons in the PVN and SON exist. The phosphorylated form was also observed in the rat hypophysis. Moreover, phospho-EF2 and OT were colocalized in a part of the neurons in the PVN and SON. These results suggest that OT may be partially translated in the axons of neurons in the PVN and SON, and then secreted from the pituitary
Mechanistic target of rapamycin (mTOR) signaling genes in decapod crustaceans: cloning and tissue expression of mTOR, Akt, Rheb, and S6 kinase in the green crab, Carcinus maenas, and blackback land crab, Gecarcinus lateralis
Mechanistic target of rapamycin (mTOR) controls global translation of mRNA into protein by phosphorylating p70 S6 kinase (S6K) and eIF4E-binding protein-1. Akt and Rheb, a GTP-binding protein, regulate mTOR protein kinase activity. Molting in crustaceans is regulated by ecdysteroids synthesized by a pair of molting glands, or Y-organs (YOs), located in the cephalothorax. During premolt, the YOs hypertrophy and increase production of ecdysteroids. Rapamycin (1 μM) inhibited ecdysteroid secretion in Carcinus maenas and Gecarcinus lateralis YOs in vitro, indicating that ecdysteroidogenesis requires mTOR-dependent protein synthesis. The effects of molting on the expression of four key mTOR signaling genes (mTOR, Akt, Rheb, and S6K) in the YO was investigated. Partial cDNAs encoding green crab (C. maenas) mTOR (4031 bp), Akt (855 bp), and S6K (918 bp) were obtained from expressed sequence tags. Identity/similarity of the deduced amino acid sequence of the C. maenas cDNAs to human orthologs were 72%/81% for Cm-mTOR, 58%/73% for Cm-Akt, and 77%/88% for Cm-S6K. mTOR, Akt, S6K, and elongation factor 2 (EF2) in C. maenas and blackback land crab (G. lateralis) were expressed in all tissues examined. The two species differed in the effects of molting on gene expression in the YO. In G. lateralis, Gl-mTOR, Gl-Akt, and Gl-EF2 mRNA levels were increased during premolt. By contrast, molting had no effect on the expression of Cm-mTOR, Cm-Akt, Cm-S6K, Cm-Rheb, and Cm-EF2. These data suggest that YO activation during premolt involves up regulation of mTOR signaling genes in G. lateralis, but is not required in C. maenas
Atomtronics with a spin: statistics of spin transport and non-equilibrium orthogonality catastrophe in cold quantum gases
We propose to investigate the full counting statistics of nonequilibrium spin
transport with an ultracold atomic quantum gas. The setup makes use of the spin
control available in atomic systems to generate spin transport induced by an
impurity atom immersed in a spin-imbalanced two-component Fermi gas. In
contrast to solid-state realizations, in ultracold atoms spin relaxation and
the decoherence from external sources is largely suppressed. As a consequence,
once the spin current is turned off by manipulating the internal spin degrees
of freedom of the Fermi system, the nonequilibrium spin population remains
constant. Thus one can directly count the number of spins in each reservoir to
investigate the full counting statistics of spin flips, which is notoriously
challenging in solid state devices. Moreover, using Ramsey interferometry, the
dynamical impurity response can be measured. Since the impurity interacts with
a many-body environment that is out of equilibrium, our setup provides a way to
realize the non-equilibrium orthogonality catastrophe. Here, even for spin
reservoirs initially prepared in a zero-temperature state, the Ramsey response
exhibits an exponential decay, which is in contrast to the conventional
power-law decay of Anderson's orthogonality catastrophe. By mapping our system
to a multi-step Fermi sea, we are able to derive analytical expressions for the
impurity response at late times. This allows us to reveal an intimate
connection of the decay rate of the Ramsey contrast and the full counting
statistics of spin flips.Comment: 9+11 pages, 10 figure
Band-edge BCS-BEC crossover in a two-band superconductor: physical properties and detection parameters
Superconductivity in iron-based, magnesium diborides, and other novel
superconducting materials has a strong multi-band and multi-gap character.
Recent experiments support the possibillity for a BCS-BEC crossover induced by
strong-coupling and proximity of the chemical potential to the band edge of one
of the bands. Here we study the simplest theoretical model which accounts for
the BCS-BEC crossover in a two-band superconductor, considering tunable
interactions and tunable energy separations between the bands. Mean-field
results for condensate fraction, correlation length, and superconducting gap
are reported in typical crossover diagrams to locate the boundaries of the BCS,
crossover, and BEC regimes. When the superconducting gap is of the order of the
local chemical potential, superconductivity is in the crossover regime of the
BCS-BEC crossover and the Fermi surface of the small band is smeared by the gap
opening. In this situation, small and large Cooper pairs coexist in the total
condensate, which is the optimal condition for high-Tc superconductivity. The
ratio between the gap and the Fermi energy in a given band results to be the
best detection parameter for experiments to locate the system in the BCS-BEC
crossover. Using available experimental data, our analysis shows that
iron-based superconductors have the partial condensate of the small Fermi
surface in the crossover regime of the BCS-BEC crossover, supporting the recent
ARPES findings.Comment: 10 pages, 8 figures, submitted to SUST (Multicomponent
Superconductivity
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