The nose and tongue as chemical detectors

Human chemical senses are the gatekeepers of our digestive system. Chemical separation combined with human sensory perception has been used to isolate and identify a natural non-steroidal anti-inflammatory compound in olive oil.<br /

Marker profile of digestive system organs comorbid pathology in children

The article highlights the current state of the comorbid pathology of the digestive system problem in children. Attention is paid to the most significant trigger factors of comorbid pathology of the digestive system organs in children and they are given a prognostic assessment with the development of a mathematical model of developmental risk.Aim. To identify predictors of comorbid pathology of the digestive system in children and to determine their prognostic value.Material and methods. 115 children with comorbid pathology of the digestive system organs and 80 healthy children aged 7-18 years were examined. The state of biological, social and genealogical well-being was determined by means of questionnaires. Laboratory and instrumental studies were conducted in accordance to the Ministry of Health ofUkraineorders in the specialty "Pediatric Gastroenterology" with the informed consent of patients to participate in the study.Results. Etiologically determining risk factors for the development of comorbid pathology of the digestive system organs in children are unfavorable genealogical history with hereditary burden by both pedigrees, age and sex of the child, H. pylori infection, stress, vitamin D3 and iodine deficiency, endothelial dysfunction, disruptions of regional blood flow in the abdominal trunk, premorbid background.Conclusion. It is established that the risk of comorbid pathology of the digestive system in children will increase by 4.27 times if the child has identified by us non-modifying factors, and by 2.62 times under the influence of modifying factors

Analisis Kebutuhan Media Ular Tangga pada Pembelajaran IPA Materi Sistem Pencernaan Manusia

The aim of this research is to analyze the need for snakes and ladders media in science learning material on the human digestive system. The needs analysis was carried out based on the ADDIE development model at the analysis stage. The research subjects were 35 class VIII students at SMPN 13 Satarmese. Data collection techniques were carried out by observing during learning, distributing questionnaires to class VIII students. The results of the analysis show that as many as 70% of students stated that teachers have not used learning media in science learning and material on the human digestive system, as many as 66% of students stated that during science learning they had difficulty understanding the material, especially the digestive system, and as many as 70% Students need learning media to study the digestive system material, and 70% of students want snakes and ladders media in learning

A review on the food digestion in the digestive tract and the used in vitro models

It is crucial to replicate or mimic the human digestive system conditions closely in model systems to have the food digestion-related data as accurate as possible. Thus, the data obtained could contribute to studies like those on the relationship between health and nutrition. This review aims to express the human digestion system’s role in food digestion and compare the capability of the models used in simulations, especially the dynamicin vitromodels. Activities of the human digestive system governing food digestion and the food matrix’s disintegration mechanism in the digestive system were discussed. Dynamicin vitromodels and their relevance to the human digestive system were described. Advancements in the last 20 years, as well as limitations of those artificial systems, with prospects, were discussed. Extensive use and improvement on these models will extend our knowledge of the food matrix and digestive system’s complex interaction. Thus, it will be possible to design next-generation foods with improved health benefits

Fascin-1 and Digestive System Carcinoma

Invasion and metastasis are major reason for poor prognosis of digestive system carcinoma patients. Motility and migratory capacity are important in contributing to tumor cells’ invasion and metastasis. Fascin is one of actin cross-linking proteins and can participate in forming parallel actin bundles in cell protrusions. Fascin-1 is consequently involved in cell adhesion, motility, and signaling. In cultured cells, over-expression of fascin-1 can increase migration and invasion capacity of cells. Many studies show up-expressions of fascin-1 are significantly associated with worse prognosis, poor differentiation, TNM stage, positive for lymph node metastasis, and positive for distant metastasis in digestive system carcinoma patients. So fascin-1 may have prognostic value as an early biomarker for more aggressive digestive system carcinoma. This review provides detailed account of preclinical studies conducted to determine the utility of fascin-1 as a therapeutic and predictive agent in invasion and metastasis of carcinomas

Psoriasis vulgaris and digestive system disorders: is there a linkage?

Psoriasis is well-known immune-mediated skin disease often associated with co-morbidities, including dyslipidaemia and obesity. Few reports imply that the disease might be also related to pathology of mucosal surfaces, especially that of the digestive system. The authors present a case of psoriasis and concurrent digestive system abnormalities, and review the literature regarding the topic. A 40-year-old man suffered from an exacerbation of exudative psoriasis for about 6 months. Topical antipsoriatics proved ineffective and the disease gradually progressed to a severe disseminated form. Subsequent detailed examinations revealed persistent gastroduodenitis due to H. pylori infection, pancreatic dysfunction and fatty change of the liver, although the patient denied any gastrointestinal symptoms. As a result appropriate treatment of the diagnosed digestive system disorders was added to topical antipsoriatic therapy. Within 2 weeks of treatment clinical symptoms and laboratory signs showed a marked trend to normalisation. The presented medical history seems to suggest that there may be some kind of interplay between psoriasis and digestive system disorders

Digestive System and Endocrine System

Exam paper (Supplementary) for second semester 201

Pengembangan Media Permainan Biology Racing Game Materi Sistem Pencernaan pada Manusia

The research background is based on the boredom of the students, the less active students, and students’ difficulties in understanding the matter and the less effective teaching methods to enhance student activity. The use of Biology Racing Game media in the matter of human digestive system hopefully can solve the problems. The purpose of this research is to produce Biology Racing Game media in the matter of human digestive system. This research is a development research using 4D models. However it was done until the development stage. The media was reviewed by a media lecturer, a human anatomy and physiology lecturer and a biology teacher due to the media formats, the appearance of media and validity of concepts. The results show that the media is feasible. Based on the result of the research, Biology Racing Game media of human digestive system is suitable for being used as an understanding concept reinforcement. Keyword: Biology Racing Game, human digestive system

A putative probiotic isolated from hatchery reared juvenile Penaeus monodon

Probiotic is considered as a remedy to solve disease problem in shrimp aquaculture. Shrimp body and environment bacterial flora are recommended as reliable source for extracting of beneficial bacteria. Therefore, 5000 pieces of post larvae of Penaeus monodon were distributed equally in 4 tanks in probiotic and antibiotic free condition up to juvenile. Then microbiological samples from digestive system, muscles, body surface, rearing water and tank sediment were inoculated onto the selective media plates. Incident of total bacteria, Vibrio, Pseudomonas and Entrobacteriaceae were evaluated in different body parts and rearing environment of shrimp. The highest bacteria count for total bacteria, Vibrio, Pseudomonas was occurred in sediment followed by digestive system. No Entrobacteriaceae was observed from all samples. Isolated bacteria were identified and placed in 7 genera consisted of Vibrio, Shewanella, Burkholderia, Clavibacter, Staphylococcus, Brevibacterium, Corynebacterium, while one genus remained unidentified. Genus Shewanella exhibited highest frequent bacteria in digestive system of P. monodon which may be indicated its ability to colonization in digestive system. Shewanella algae was selected from whole isolated bacteria as candidate probiotic via well plate diffusion technique and cross streak antagonistic test against Vibrio harveyi, V. parahaemolyticus and V. alginolyticus. It was able to digest lipid and protein in tributyrin agar and skim milk agar