Advanced medical micro-robotics for early diagnosis and therapeutic interventions

Recent technological advances in micro-robotics have demonstrated their immense potential for biomedical applications. Emerging micro-robots have versatile sensing systems, flexible locomotion and dexterous manipulation capabilities that can significantly contribute to the healthcare system. Despite the appreciated and tangible benefits of medical micro-robotics, many challenges still remain. Here, we review the major challenges, current trends and significant achievements for developing versatile and intelligent micro-robotics with a focus on applications in early diagnosis and therapeutic interventions. We also consider some recent emerging micro-robotic technologies that employ synthetic biology to support a new generation of living micro-robots. We expect to inspire future development of micro-robots toward clinical translation by identifying the roadblocks that need to be overcome

Scalable Three-Dimensional Grasping Mechanism

In this work, we develop a scalable end-effector mechanism for grasping three- dimensional objects with sizes ranging from micrometer to millimeter scale. The design architecture of the gripper comprises an array of identical fingers patented in a circular fashion. Each finger is designed from a novel linkage mechanism whose end effector is manipulated by two independent actuators. In this research, we study three finger gripper device, where each is obtained from a 3 - linkage mechanism. The device is controlled by three independent piezo actuators, and one electro-magnetic solenoid common to each mechanism. The gripping capability depends on how fingers are controlled collectively and on the mechanical flexibility, which together provide variety of gripping performances that are necessary to handle a wide variety of objects. The gripping performance is defined here by grasping force at contact, motion range, and bandwidth. Optimization is done to design the link lengths for the best Geometric Advantage (GA), and the functionality evaluated using finite element analysis software, ANSYS

Advanced medical micro-robotics for early diagnosis and therapeutic interventions

Recent technological advances in micro-robotics have demonstrated their immense potential for biomedical applications. Emerging micro-robots have versatile sensing systems, flexible locomotion and dexterous manipulation capabilities that can significantly contribute to the healthcare system. Despite the appreciated and tangible benefits of medical micro-robotics, many challenges still remain. Here, we review the major challenges, current trends and significant achievements for developing versatile and intelligent micro-robotics with a focus on applications in early diagnosis and therapeutic interventions. We also consider some recent emerging micro-robotic technologies that employ synthetic biology to support a new generation of living micro-robots. We expect to inspire future development of micro-robots toward clinical translation by identifying the roadblocks that need to be overcome

Active fixturing: literature review and future research directions

Fixtures are used to fixate, position and support workpieces and represent a crucial tool in manufacturing. Their performance determines the result of the whole manufacturing process of a product. There is a vast amount of research done on automatic fixture layout synthesis and optimisation and fixture design verification. Most of this work considers fixture mechanics to be static and the fixture elements to be passive. However, a new generation of fixtures has emerged that has actuated fixture elements for active control of the part–fixture system during manufacturing operations to increase the end product quality. This paper analyses the latest studies in the field of active fixture design and its relationship with flexible and reconfigurable fixturing systems. First, a brief introduction is given on the importance of research of fixturing systems. Secondly, the basics of workholding and fixture design are visited, after which the state-of-the-art in active fixturing and related concepts is presented. Fourthly, part–fixture dynamics and design strategies which take these into account are discussed. Fifthly, the control strategies used in active fixturing systems are examined. Finally, some final conclusions and prospective future research directions are presented

Workshop on "Robotic assembly of 3D MEMS".

Proceedings of a workshop proposed in IEEE IROS'2007.The increase of MEMS' functionalities often requires the integration of various technologies used for mechanical, optical and electronic subsystems in order to achieve a unique system. These different technologies have usually process incompatibilities and the whole microsystem can not be obtained monolithically and then requires microassembly steps. Microassembly of MEMS based on micrometric components is one of the most promising approaches to achieve high-performance MEMS. Moreover, microassembly also permits to develop suitable MEMS packaging as well as 3D components although microfabrication technologies are usually able to create 2D and "2.5D" components. The study of microassembly methods is consequently a high stake for MEMS technologies growth. Two approaches are currently developped for microassembly: self-assembly and robotic microassembly. In the first one, the assembly is highly parallel but the efficiency and the flexibility still stay low. The robotic approach has the potential to reach precise and reliable assembly with high flexibility. The proposed workshop focuses on this second approach and will take a bearing of the corresponding microrobotic issues. Beyond the microfabrication technologies, performing MEMS microassembly requires, micromanipulation strategies, microworld dynamics and attachment technologies. The design and the fabrication of the microrobot end-effectors as well as the assembled micro-parts require the use of microfabrication technologies. Moreover new micromanipulation strategies are necessary to handle and position micro-parts with sufficiently high accuracy during assembly. The dynamic behaviour of micrometric objects has also to be studied and controlled. Finally, after positioning the micro-part, attachment technologies are necessary

Design and experimental validation of a piezoelectric actuator tracking control based on fuzzy logic and neural compensation

This work proposes two control feedback-feedforward algorithms, based on fuzzy logic in combination with neural networks, aimed at reducing the tracking error and improving the actuation signal of piezoelectric actuators. These are frequently used devices in a wide range of applications due to their high precision in micro- and nanopositioning combined with their mechanical stiffness. Nevertheless, the hysteresis is one the main phenomenon that degrades the performance of these actuators in tracking operations. The proposed control schemes were tested experimentally in a commercial piezoelectric actuator. They were implemented with a dSPACE 1104 device, which was used for signal generation and acquisition purposes. The performance of the proposed control schemes was compared to conventional structures based on proportional-integral-derivative and fuzzy logic in feedback configuration. Experimental results show the advantages of the proposed controllers, since they are capable of reducing the error to significant magnitude orders.The authors wish to express their gratitude to the Basque Government, through the project EKOHEGAZ (ELKARTEK KK-2021/00092), to the Diputación Foral de Álava (DFA), through the project CONAVANTER, and to the UPV/EHU, through the project GIU20/063, for supporting this work

A comparative review of artificial muscles for microsystem applications

Artificial muscles are capable of generating actuation in microsystems with outstanding compliance. Recent years have witnessed a growing academic interest in artificial muscles and their application in many areas, such as soft robotics and biomedical devices. This paper aims to provide a comparative review of recent advances in artificial muscle based on various operating mechanisms. The advantages and limitations of each operating mechanism are analyzed and compared. According to the unique application requirements and electrical and mechanical properties of the muscle types, we suggest suitable artificial muscle mechanisms for specific microsystem applications. Finally, we discuss potential strategies for energy delivery, conversion, and storage to promote the energy autonomy of microrobotic systems at a system level

Pjezorobotų trajektorijų valdymas nanopalydovų stabilizavimui

Rapid industrial advancement requires novel ideas, new scientific approaches and effective technologies that would ensure quality and precision. Application of piezoelectric actuators in robotics opens many possibilities to create systems with extreme precision and control. A very important step in the development of autonomous robots is the formation of motion trajectories. Classical interpolation methods used for formation of the trajectories are suitable only when robots have wheels, legs or other parts for motion transmission. Piezorobots that are analyzed in this dissertation have no additional components that create motion, only contact points with the static plane. Therefore, traditional motion formation methods are not suitable and a problem arises how to define motion trajectory of such device. The aim of this work is to create a trajectory control algorithm of multi-degrees-of-freedom piezorobot used for nanosatellite stabilization. In order to achieve the objective, the following tasks had to be solved: to analyze constructions of precise piezorobots, their operating principles and motion formation methods; to analyze stabilization problems of satellites and application of multi-degrees-of-freedom piezorobots for nanosatellite stabilization; to create piezorobots’ motion formation algorithms according to electrode excitation schemes, to perform an experimental research; to determine quantitative characteristics of the constructed piezorobots and their motion trajectories. The introduction describes the importance and novelty of this thesis, goals of this work, its practical value and defended statements. The first chapter analyses the principals of ultrasonic devices, gives a thorough review of constructions of ultrasonic devices with multi-degrees-of-freedom. The second chapter provides a review of satellite stabilization principles and how multi-degrees-of-freedom piezorobots can be applied for nanosatellite stabilization. Motion formation methods for ultrasonic devices with multi-degrees-of-freedom are presented. The third chapter presents the detailed analysis of different piezorobots. In the fourth chapter experimental results are provided. Trajectory planning of piezorobot is shown, results are compared to numerical calculations performed in the third chapter. The conclusions about applicability of piezorobots’ motion formation algorithms according to electrode excitation schemes are given. Seven articles focusing on the subject of the dissertation have been published, two presentations on the subject have been presented in conferences at international level. The research for the dissertation has been funded by the Lithuanian State Science and Studies Foundation: European Regional Development Fund, Project No. DOTSUT-234 and Research Council of Lithuania, Project No. MIP-084/2015.Dissertatio