1,360,197 research outputs found

    Influence of concrete composition on chloride ingress and carbonation : analysis by means of an extended data-set

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    In 2015 an IWT-TETRA project, called DurOBet, was initiated focusing on service life design assessment according to different chloride diffusion and carbonation models applied on Belgian concrete mixtures. The main purpose of this research project is to develop a quantitative method for a service-life based design of concrete structures, more particular applicable for the Belgian concrete industry. In this way an improvement of the deemed-to-satisfy approach of the EN206-1 code can be established which is more reliable with regards to service life predictions of concrete structures. In the framework of this DurOBet project it was decided to develop an extensive database incorporating concrete related results on i) fresh properties, ii) hardened properties and iii) durability related properties such as porosity, permeability and more specifically on chloride ingress and carbonation. The data originate from numerous journal articles and conference papers, doctoral research projects and master thesis studies. At this time more than 100 papers or studies were investigated, reported between 1992 and 2016, generating a dataset of over a thousand unique concrete recipes, geographically spread but with focus on the concrete mixes applicable for the Belgian industry. Both traditional and self-compacting concrete mixes are incorporated into the database. This database is being used for the analysis of the durability related properties, such as the chloride diffusion and carbonation coefficient, and their relation with mix proportioning parameters of the concrete mixtures (cement or binder content, type of binder, water-to-binder ratio,…). The main focus of this paper is to highlight the framework of the database: the mix proportioning of the concrete mixes is being discussed and the origin of the concrete data (country, reference info, etc.). By means of data mining and some known relations with respect to the durability related properties, e.g. correlation between w/b-ratio and chloride diffusion coefficient, are being evaluated

    Bcipep: A database of B-cell epitopes

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    BACKGROUND: Bcipep is a database of experimentally determined linear B-cell epitopes of varying immunogenicity collected from literature and other publicly available databases. RESULTS: The current version of Bcipep database contains 3031 entries that include 763 immunodominant, 1797 immunogenic and 471 null-immunogenic epitopes. It covers a wide range of pathogenic organisms like viruses, bacteria, protozoa, and fungi. The database provides a set of tools for the analysis and extraction of data that includes keyword search, peptide mapping and BLAST search. It also provides hyperlinks to various databases such as GenBank, PDB, SWISS-PROT and MHCBN. CONCLUSION: A comprehensive database of B-cell epitopes called Bcipep has been developed that covers information on epitopes from a wide range of pathogens. The Bcipep will be source of information for investigators involved in peptide-based vaccine design, disease diagnosis and research in allergy. It should also be a promising data source for the development and evaluation of methods for prediction of B-cell epitopes. The database is available at

    Pengembangan Database Evaluasi Kinerja Dosen Berbasis Android di STKIP PGRI Lubuklinggau

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    The purpose of this research is to manage an android-based lecturer performance database. The approach in this study uses a systems approach with a waterfall model. The steps in developing the model are; 1) requirements analysis, 2) design, 3) implementation and unit testing. 4) integration and system test. The results of the study, the results of the database expert validation include; study programs, lecturers, courses, classes, students, and reports are appropriate to use. Website expert validation is carried out on 5 indicators, namely; a) content, b) readibility, c) speed, d) technological sophistication, and e) access worth using. Conclusion, Implementation of android-based lecturer performance database is feasible to use. Keywords: Android, Database, Lecturer Performance   &nbsp

    PathCase-SB architecture and database design

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    <p>Abstract</p> <p>Background</p> <p>Integration of metabolic pathways resources and regulatory metabolic network models, and deploying new tools on the integrated platform can help perform more effective and more efficient systems biology research on understanding the regulation in metabolic networks. Therefore, the tasks of (a) integrating under a single database environment regulatory metabolic networks and existing models, and (b) building tools to help with modeling and analysis are desirable and intellectually challenging computational tasks.</p> <p>Description</p> <p>PathCase Systems Biology (PathCase-SB) is built and released. The PathCase-SB database provides data and API for multiple user interfaces and software tools. The current PathCase-SB system provides a database-enabled framework and web-based computational tools towards facilitating the development of kinetic models for biological systems. PathCase-SB aims to integrate data of selected biological data sources on the web (currently, BioModels database and KEGG), and to provide more powerful and/or new capabilities via the new web-based integrative framework. This paper describes architecture and database design issues encountered in PathCase-SB's design and implementation, and presents the current design of PathCase-SB's architecture and database.</p> <p>Conclusions</p> <p>PathCase-SB architecture and database provide a highly extensible and scalable environment with easy and fast (real-time) access to the data in the database. PathCase-SB itself is already being used by researchers across the world.</p

    SKPDB: a structural database of shikimate pathway enzymes

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    <p>Abstract</p> <p>Background</p> <p>The functional and <b>s</b>tructural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main interest in studying shikimate pathway enzymes involves the fact that they are essential for bacteria but do not occur in humans, making them selective targets for design of drugs that do not directly impact humans.</p> <p>Description</p> <p>The ShiKimate Pathway DataBase (SKPDB) is a relational database applied to the study of shikimate pathway enzymes in microorganisms and plants. The current database is updated regularly with the addition of new data; there are currently 8902 enzymes of the shikimate pathway from different sources. The database contains extensive information on each enzyme, including detailed descriptions about sequence, references, and structural and functional studies. All files (primary sequence, atomic coordinates and quality scores) are available for downloading. The modeled structures can be viewed using the Jmol program.</p> <p>Conclusions</p> <p>The SKPDB provides a large number of structural models to be used in docking simulations, virtual screening initiatives and drug design. It is freely accessible at <url>http://lsbzix.rc.unesp.br/skpdb/</url>.</p

    Processing and Analysis of Condensation Trails Data Using Database Systems

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    This article describes the causes and behavior of aircraft condensation trails, aircraft radar technology, communication between aircraft and ground control stations, description of the function, analysis and processing of the ADS-B receivers and registers data. It also deals with the design and creation of a suitable web application with a simple user interface and a database for storing and processing this data. The work was based mainly on academical materials and sources, focusing on the issue of condensation trails, ADS-B functionality and programming of web applications

    TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico

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    Rapid advancing computational technologies have greatly speeded up the development of computer-aided drug design (CADD). Recently, pharmaceutical companies have increasingly shifted their attentions toward traditional Chinese medicine (TCM) for novel lead compounds. Despite the growing number of studies on TCM, there is no free 3D small molecular structure database of TCM available for virtual screening or molecular simulation. To address this shortcoming, we have constructed TCM Database@Taiwan (http://tcm.cmu.edu.tw/) based on information collected from Chinese medical texts and scientific publications. TCM Database@Taiwan is currently the world's largest non-commercial TCM database. This web-based database contains more than 20,000 pure compounds isolated from 453 TCM ingredients. Both cdx (2D) and Tripos mol2 (3D) formats of each pure compound in the database are available for download and virtual screening. The TCM database includes both simple and advanced web-based query options that can specify search clauses, such as molecular properties, substructures, TCM ingredients, and TCM classification, based on intended drug actions. The TCM database can be easily accessed by all researchers conducting CADD. Over the last eight years, numerous volunteers have devoted their time to analyze TCM ingredients from Chinese medical texts as well as to construct structure files for each isolated compound. We believe that TCM Database@Taiwan will be a milestone on the path towards modernizing traditional Chinese medicine.National Science Council of Taiwan (NSC 99-2221-E-039-013-)China Medical UniversityAsia UniversityAsia University (CMU98-ASIA-09)Taiwan. Dept. of Health (Clinical Trial and Research Center of Excellence (DOH99-TD-B-111-004))Taiwan. Dept. of Health (Cancer Research Center of Excellence (DOH99-TD-C-111-005)

    Designing interoperable museum information systems

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    Museum collections are characterized by heterogeneity, since they usually host a plethora of objects of categories, while each of them requires different description policies and metadata standards. Moreover the museum records, which keep the history and evolution of the hosted collections, request proactive curation in order to preserve this rich and diverse information. In this paper, the architecture of an innovative museum information system, as well as its implementation details is presented. In particular the requirements and the system architecture are presented along with the problems that were encountered. The main directions of the system design are (a) to increase interoperability levels and therefore assist proactive curation and (b) to enhance navigation by the usage of handheld devices. The first direction is satisfied by the design of a rich metadata schema based on the CIDOC/CRM standard. The second direction is fulfilled by the implementation of a module, which integrates the museum database with a subsystem appropriate to support user navigation into the museum floors and rooms. The module is expressed as a navigation functionality, which is accessed through handheld devices and peripherals, such as PDAs and RFID tags. The proposed system is functional and operates into the Solomos Museum, situated in Zakynthos island, Greece
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