Patient-Centric Knowledge Graphs: A Survey of Current Methods, Challenges, and Applications

Patient-Centric Knowledge Graphs (PCKGs) represent an important shift in healthcare that focuses on individualized patient care by mapping the patient's health information in a holistic and multi-dimensional way. PCKGs integrate various types of health data to provide healthcare professionals with a comprehensive understanding of a patient's health, enabling more personalized and effective care. This literature review explores the methodologies, challenges, and opportunities associated with PCKGs, focusing on their role in integrating disparate healthcare data and enhancing patient care through a unified health perspective. In addition, this review also discusses the complexities of PCKG development, including ontology design, data integration techniques, knowledge extraction, and structured representation of knowledge. It highlights advanced techniques such as reasoning, semantic search, and inference mechanisms essential in constructing and evaluating PCKGs for actionable healthcare insights. We further explore the practical applications of PCKGs in personalized medicine, emphasizing their significance in improving disease prediction and formulating effective treatment plans. Overall, this review provides a foundational perspective on the current state-of-the-art and best practices of PCKGs, guiding future research and applications in this dynamic field

Looking for a Black Cat in a Dark Room: Security Visualization for Cyber-Physical System Design and Analysis

Today, there is a plethora of software security tools employing visualizations that enable the creation of useful and effective interactive security analyst dashboards. Such dashboards can assist the analyst to understand the data at hand and, consequently, to conceive more targeted preemption and mitigation security strategies. Despite the recent advances, model-based security analysis is lacking tools that employ effective dashboards---to manage potential attack vectors, system components, and requirements. This problem is further exacerbated because model-based security analysis produces significantly larger result spaces than security analysis applied to realized systems---where platform specific information, software versions, and system element dependencies are known. Therefore, there is a need to manage the analysis complexity in model-based security through better visualization techniques. Towards that goal, we propose an interactive security analysis dashboard that provides different views largely centered around the system, its requirements, and its associated attack vector space. This tool makes it possible to start analysis earlier in the system lifecycle. We apply this tool in a significant area of engineering design---the design of cyber-physical systems---where security violations can lead to safety hazards

Proceedings of the 2020 Joint Workshop of Fraunhofer IOSB and Institute for Anthropomatics, Vision and Fusion Laboratory

In 2020 fand der jährliche Workshop des Faunhofer IOSB und the Lehrstuhls für interaktive Echtzeitsysteme statt. Vom 27. bis zum 31. Juli trugen die Doktorranden der beiden Institute über den Stand ihrer Forschung vor in Themen wie KI, maschinellen Lernen, computer vision, usage control, Metrologie vor. Die Ergebnisse dieser Vorträge sind in diesem Band als technische Berichte gesammelt

Bibliographical review on cyber attacks from a control oriented perspective

This paper presents a bibliographical review of definitions, classifications and applications concerning cyber attacks in networked control systems (NCSs) and cyber-physical systems (CPSs). This review tackles the topic from a control-oriented perspective, which is complementary to information or communication ones. After motivating the importance of developing new methods for attack detection and secure control, this review presents security objectives, attack modeling, and a characterization of considered attacks and threats presenting the detection mechanisms and remedial actions. In order to show the properties of each attack, as well as to provide some deeper insight into possible defense mechanisms, examples available in the literature are discussed. Finally, open research issues and paths are presented.Peer ReviewedPostprint (author's final draft

SoK: Cryptographically Protected Database Search

Protected database search systems cryptographically isolate the roles of reading from, writing to, and administering the database. This separation limits unnecessary administrator access and protects data in the case of system breaches. Since protected search was introduced in 2000, the area has grown rapidly; systems are offered by academia, start-ups, and established companies. However, there is no best protected search system or set of techniques. Design of such systems is a balancing act between security, functionality, performance, and usability. This challenge is made more difficult by ongoing database specialization, as some users will want the functionality of SQL, NoSQL, or NewSQL databases. This database evolution will continue, and the protected search community should be able to quickly provide functionality consistent with newly invented databases. At the same time, the community must accurately and clearly characterize the tradeoffs between different approaches. To address these challenges, we provide the following contributions: 1) An identification of the important primitive operations across database paradigms. We find there are a small number of base operations that can be used and combined to support a large number of database paradigms. 2) An evaluation of the current state of protected search systems in implementing these base operations. This evaluation describes the main approaches and tradeoffs for each base operation. Furthermore, it puts protected search in the context of unprotected search, identifying key gaps in functionality. 3) An analysis of attacks against protected search for different base queries. 4) A roadmap and tools for transforming a protected search system into a protected database, including an open-source performance evaluation platform and initial user opinions of protected search.Comment: 20 pages, to appear to IEEE Security and Privac

Blockchain Value Creation Logics and Financial Returns

With its complexities and portfolio-nature, the advent of blockchain technology presents several use cases to stakeholders for business value appropriation and financial gains. This 3-essay dissertation focuses on three exemplars and research approaches to understanding the value creation logics of blockchain technology for financial gains. The first essay is a conceptual piece that explores five main affordances of blockchain technology and how these can be actualized and assimilated for business value. Based on the analysis of literature findings, an Affordance-Experimentation-Actualization-Assimilation (AEAA) model is proposed. The model suggests five affordance-to-assimilation value chains and eight value interdependencies that firms can leverage to optimize their value creation and capture during blockchain technology implementation. The second essay empirically examines the financial returns of public firms\u27 blockchain adoption investments at the level of the three main blockchain archetypes (private-permissioned, public-permissioned and permissionless. Drawing upon Fichman\u27s model of the option value of innovative IT platform investments, the study examines business value creation through firm blockchain strategy (i.e., archetype instances, decentralization, and complementarity), learning (i.e., blockchain patents and event participation), and bandwagon effects using quarterly data of firm archetype investments from 2015 to 2020. The study\u27s propensity score matching utilization and fixed-effects modeling provide objective quantification of how blockchain adoption leads to increases in firm value (performance measured by Tobin\u27s q) at the archetype level (permissionless, public permissioned, and private permissioned). Surprisingly, a more decentralized archetype and a second different archetype implementation are associated with a lower Tobin\u27s q. In addition, IT-option proxy parameters such as blockchain patent originality, participation in blockchain events, and network externality positively impact firm performance, whereas the effect of blockchain patents is negative. As the foremost and more established use case of blockchain technology whose business value is accessed in either of the five affordances and exemplifies a permissionless archetype for financial gains, bitcoin cryptocurrency behavior is studied through the lens of opinion leaders on Twitter. The third essay this relationship understands the hourly price returns and volatility shocks that sentiments from opinion leaders generate and vice-versa. With a dynamic opinion leader identification strategy, lexicon and rule-based sentiment analytics, I extract sentiments of the top ten per cent bitcoin opinion leaders\u27 tweets. Controlling for various economic indices and contextual factors, the study estimates a vector autoregression model (VAR) and finds that finds that Bitcoin return granger cause Polarity but the influence of sentiment subjectivity is marginal and only stronger on bitcoin price volatility. Several key implications for blockchain practitioners and financial stakeholders and suggestions for future research are discussed

Content sensitivity based access control model for big data

Big data technologies have seen tremendous growth in recent years. They are being widely used in both industry and academia. In spite of such exponential growth, these technologies lack adequate measures to protect the data from misuse or abuse. Corporations that collect data from multiple sources are at risk of liabilities due to exposure of sensitive information. In the current implementation of Hadoop, only file level access control is feasible. Providing users, the ability to access data based on attributes in a dataset or based on their role is complicated due to the sheer volume and multiple formats (structured, unstructured and semi-structured) of data. In this dissertation an access control framework, which enforces access control policies dynamically based on the sensitivity of the data is proposed. This framework enforces access control policies by harnessing the data context, usage patterns and information sensitivity. Information sensitivity changes over time with the addition and removal of datasets, which can lead to modifications in the access control decisions and the proposed framework accommodates these changes. The proposed framework is automated to a large extent and requires minimal user intervention. The experimental results show that the proposed framework is capable of enforcing access control policies on non-multimedia datasets with minimal overhea

Who wrote this scientific text?

The IEEE bibliographic database contains a number of proven duplications with indication of the original paper(s) copied. This corpus is used to test a method for the detection of hidden intertextuality (commonly named "plagiarism"). The intertextual distance, combined with the sliding window and with various classification techniques, identifies these duplications with a very low risk of error. These experiments also show that several factors blur the identity of the scientific author, including variable group authorship and the high levels of intertextuality accepted, and sometimes desired, in scientific papers on the same topic

Applications

Volume 3 describes how resource-aware machine learning methods and techniques are used to successfully solve real-world problems. The book provides numerous specific application examples: in health and medicine for risk modelling, diagnosis, and treatment selection for diseases in electronics, steel production and milling for quality control during manufacturing processes in traffic, logistics for smart cities and for mobile communications