1,160 research outputs found

    The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species

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    The Mediterranean fruit fly (medfly), Ceratitis capitata, is a major destructive insect pest due to its broad host range, which includes hundreds of fruits and vegetables. It exhibits a unique ability to invade and adapt to ecological niches throughout tropical and subtropical regions of the world, though medfly infestations have been prevented and controlled by the sterile insect technique (SIT) as part of integrated pest management programs (IPMs). The genetic analysis and manipulation of medfly has been subject to intensive study in an effort to improve SIT efficacy and other aspects of IPM control

    2015 Summer Research Symposium Abstract Book

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    2015 Summer volume of abstracts for science research projects conducted by students at Trinity College

    Calmodulin Enhances Cryptochrome Binding to INAD in Drosophila Photoreceptors

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    Light is the main environmental stimulus that synchronizes the endogenous timekeeping systems in most terrestrial organisms. Drosophila cryptochrome (dCRY) is a light-responsive flavoprotein that detects changes in light intensity and wavelength around dawn and dusk. We have previously shown that dCRY acts through Inactivation No Afterpotential D (INAD) in a light-dependent manner on the Signalplex, a multiprotein complex that includes visual-signaling molecules, suggesting a role for dCRY in fly vision. Here, we predict and demonstrate a novel Ca2+-dependent interaction between dCRY and calmodulin (CaM). Through yeast two hybrid, coimmunoprecipitation (Co-IP), nuclear magnetic resonance (NMR) and calorimetric analyses we were able to identify and characterize a CaM binding motif in the dCRY C-terminus. Similarly, we also detailed the CaM binding site of the scaffold protein INAD and demonstrated that CaM bridges dCRY and INAD to form a ternary complex in vivo. Our results suggest a process whereby a rapid dCRY light response stimulates an interaction with INAD, which can be further consolidated by a novel mechanism regulated by CaM

    PROGRAM and PROCEEDINGS THE NEBRASKA ACADEMY OF SCIENCES 1880-2017 Including the Nebraska Association of Teachers of Science (NATS) Division Nebraska Junior Academy of Sciences (NJAS) Affiliate and Affiliated Societies

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    FRIDAY, APRIL 21, 2017 7:30 a.m. REGISTRATION FOR ACADEMY, Lobby of Lecture wing, Olin Hall 8:00 Aeronautics and Space Science, Session A, Olin 249 Aeronautics and Space Science, Session B, Olin 224 Chemistry and Physics, Section A, Chemistry, Olin A Collegiate Academy, Biology, Session A, Olin B Collegiate Academy, Biology, Session B, Olin 112 Collegiate Academy, Chemistry and Physics, Session A, Olin 324 8:30 Biological and Medical Sciences, Session A, Smith Callen Conference Center 9:10 Aeronautics and Space Science, Poster Session, Olin 249 9:40 Applied Science and Technology, Olin 325 10:00 Chemistry and Physics, Physics, Section B, Planetarium 10:30 Aeronautics and Space Science, Poster Session, Olin 249 11:00 MAIBEN MEMORIAL LECTURE, OLIN B – Scholarship and Friend of Science Recipients also announced. 12:00 LUNCH, PATIO ROOM, STORY STUDENT CENTER Aeronautics Group, Sunflower Room 1:00 p.m. Anthropology, Olin 111 Biological and Medical Sciences, Session B, Smith Callen Conference Center Collegiate Academy, Biology, Session A, Olin B Collegiate Academy, Biology, Session B, Olin 112 Collegiate Academy, Chemistry and Physics, Session B, Olin 324 Earth Science, Olin 249 1:05 Applied Science and Technology, Olin 325 1:15 Teaching of Science and Math, Olin 224 Chemistry and Physics, Section A, Chemistry, Olin A 2:45 Environmental Sciences, Olin 249 4:30 BUSINESS MEETING, OLIN B Abstracts of papers 2016-2017 EXECUTIVE COMMITTEE 2016-2017 PROGRAM COMMITTEE 2016-2017 POLICY COMMITTEE FRIENDS OF THE ACADEMY FRIEND OF SCIENCE AWARD WINNERS FRIEND OF SCIENCE AWARD TO KACIE BAUM FRIEND OF SCIENCE AWARD TO TODD YOUNG Author Index 141 p

    Calmodulin enhances cryptochrome binding to INAD in Drosophila photoreceptors

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    Light is the main environmental stimulus that synchronizes the endogenous timekeeping systems in most terrestrial organisms. Drosophila cryptochrome (dCRY) is a light-responsive flavoprotein that detects changes in light intensity and wavelength around dawn and dusk. We have previously shown that dCRY acts through Inactivation No Afterpotential D (INAD) in a light-dependent manner on the Signalplex, a multiprotein complex that includes visual-signaling molecules, suggesting a role for dCRY in fly vision. Here, we predict and demonstrate a novel Ca2+-dependent interaction between dCRY and calmodulin (CaM). Through yeast two hybrid, coimmunoprecipitation (Co-IP), nuclear magnetic resonance (NMR) and calorimetric analyses we were able to identify and characterize a CaM binding motif in the dCRY C-terminus. Similarly, we also detailed the CaM binding site of the scaffold protein INAD and demonstrated that CaM bridges dCRY and INAD to form a ternary complex in vivo. Our results suggest a process whereby a rapid dCRY light response stimulates an interaction with INAD, which can be further consolidated by a novel mechanism regulated by CaM

    16th Annual Petersheim Academic Exposition Abstracts

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    Aerospace medicine and biology: A continuing bibliography with indexes (supplement 368)

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    This bibliography lists 305 reports, articles, and other documents introduced into the NASA Scientific and Technical Information System during Sep. 1992. The subject coverage concentrates on the biological, physiological, psychological, and environmental effects to which humans are subjected during and following simulated or actual flight in the Earth's atmosphere or in interplanetary space. References describing similar effects on biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention. Applied research receives the most emphasis, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion
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