1,160 research outputs found
The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species
The Mediterranean fruit fly (medfly), Ceratitis capitata, is a major destructive insect pest due to its broad host range, which includes hundreds of fruits and vegetables. It exhibits a unique ability to invade and adapt to ecological niches throughout tropical and subtropical regions of the world, though medfly infestations have been prevented and controlled by the sterile insect technique (SIT) as part of integrated pest management programs (IPMs). The genetic analysis and manipulation of medfly has been subject to intensive study in an effort to improve SIT efficacy and other aspects of IPM control
2015 Summer Research Symposium Abstract Book
2015 Summer volume of abstracts for science research projects conducted by students at Trinity College
Calmodulin Enhances Cryptochrome Binding to INAD in Drosophila Photoreceptors
Light is the main environmental stimulus that synchronizes the endogenous timekeeping systems in most terrestrial organisms. Drosophila cryptochrome (dCRY) is a light-responsive flavoprotein that detects changes in light intensity and wavelength around dawn and dusk. We have previously shown that dCRY acts through Inactivation No Afterpotential D (INAD) in a light-dependent manner on the Signalplex, a multiprotein complex that includes visual-signaling molecules, suggesting a role for dCRY in fly vision. Here, we predict and demonstrate a novel Ca2+-dependent interaction between dCRY and calmodulin (CaM). Through yeast two hybrid, coimmunoprecipitation (Co-IP), nuclear magnetic resonance (NMR) and calorimetric analyses we were able to identify and characterize a CaM binding motif in the dCRY C-terminus. Similarly, we also detailed the CaM binding site of the scaffold protein INAD and demonstrated that CaM bridges dCRY and INAD to form a ternary complex in vivo. Our results suggest a process whereby a rapid dCRY light response stimulates an interaction with INAD, which can be further consolidated by a novel mechanism regulated by CaM
PROGRAM and PROCEEDINGS THE NEBRASKA ACADEMY OF SCIENCES 1880-2017 Including the Nebraska Association of Teachers of Science (NATS) Division Nebraska Junior Academy of Sciences (NJAS) Affiliate and Affiliated Societies
FRIDAY, APRIL 21, 2017
7:30 a.m. REGISTRATION FOR ACADEMY, Lobby of Lecture wing, Olin Hall
8:00 Aeronautics and Space Science, Session A, Olin 249
Aeronautics and Space Science, Session B, Olin 224
Chemistry and Physics, Section A, Chemistry, Olin A
Collegiate Academy, Biology, Session A, Olin B
Collegiate Academy, Biology, Session B, Olin 112
Collegiate Academy, Chemistry and Physics, Session A, Olin 324
8:30 Biological and Medical Sciences, Session A, Smith Callen Conference Center
9:10 Aeronautics and Space Science, Poster Session, Olin 249
9:40 Applied Science and Technology, Olin 325
10:00 Chemistry and Physics, Physics, Section B, Planetarium
10:30 Aeronautics and Space Science, Poster Session, Olin 249
11:00 MAIBEN MEMORIAL LECTURE, OLIN B –
Scholarship and Friend of Science Recipients also announced.
12:00 LUNCH, PATIO ROOM, STORY STUDENT CENTER
Aeronautics Group, Sunflower Room
1:00 p.m. Anthropology, Olin 111
Biological and Medical Sciences, Session B, Smith Callen Conference Center
Collegiate Academy, Biology, Session A, Olin B
Collegiate Academy, Biology, Session B, Olin 112
Collegiate Academy, Chemistry and Physics, Session B, Olin 324
Earth Science, Olin 249
1:05 Applied Science and Technology, Olin 325
1:15 Teaching of Science and Math, Olin 224
Chemistry and Physics, Section A, Chemistry, Olin A
2:45 Environmental Sciences, Olin 249
4:30 BUSINESS MEETING, OLIN B
Abstracts of papers
2016-2017 EXECUTIVE COMMITTEE
2016-2017 PROGRAM COMMITTEE
2016-2017 POLICY COMMITTEE
FRIENDS OF THE ACADEMY
FRIEND OF SCIENCE AWARD WINNERS
FRIEND OF SCIENCE AWARD TO KACIE BAUM
FRIEND OF SCIENCE AWARD TO TODD YOUNG
Author Index
141 p
Calmodulin enhances cryptochrome binding to INAD in Drosophila photoreceptors
Light is the main environmental stimulus that synchronizes the endogenous timekeeping systems in most terrestrial organisms. Drosophila cryptochrome (dCRY) is a light-responsive flavoprotein that detects changes in light intensity and wavelength around dawn and dusk. We have previously shown that dCRY acts through Inactivation No Afterpotential D (INAD) in a light-dependent manner on the Signalplex, a multiprotein complex that includes visual-signaling molecules, suggesting a role for dCRY in fly vision. Here, we predict and demonstrate a novel Ca2+-dependent interaction between dCRY and calmodulin (CaM). Through yeast two hybrid, coimmunoprecipitation (Co-IP), nuclear magnetic resonance (NMR) and calorimetric analyses we were able to identify and characterize a CaM binding motif in the dCRY C-terminus. Similarly, we also detailed the CaM binding site of the scaffold protein INAD and demonstrated that CaM bridges dCRY and INAD to form a ternary complex in vivo. Our results suggest a process whereby a rapid dCRY light response stimulates an interaction with INAD, which can be further consolidated by a novel mechanism regulated by CaM
Aerospace medicine and biology: A continuing bibliography with indexes (supplement 368)
This bibliography lists 305 reports, articles, and other documents introduced into the NASA Scientific and Technical Information System during Sep. 1992. The subject coverage concentrates on the biological, physiological, psychological, and environmental effects to which humans are subjected during and following simulated or actual flight in the Earth's atmosphere or in interplanetary space. References describing similar effects on biological organisms of lower order are also included. Such related topics as sanitary problems, pharmacology, toxicology, safety and survival, life support systems, exobiology, and personnel factors receive appropriate attention. Applied research receives the most emphasis, but references to fundamental studies and theoretical principles related to experimental development also qualify for inclusion
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