Swarming the SC’17 Student Cluster Competition

The Student Cluster Competition is a suite of challenges where teams of undergraduates design a computer cluster and then compete against each other through various benchmark applications. The present study will provide a select summary of the experiences of Team Swarm who represented the Georgia Institute of Technology at the SC’17 Student Cluster Competition. This report will first describe the competition and the members of Team Swarm. After this introduction, it focuses on three major aspects of the experience: the hardware and software architecture of the team’s computer cluster, the team’s system administration workflow and the team’s usage of cloud resources. Additionally, the appendix provides a brief description of the team members and their method of preparation.Undergraduat

A History of Audio Effects

Audio effects are an essential tool that the field of music production relies upon. The ability to intentionally manipulate and modify a piece of sound has opened up considerable opportunities for music making. The evolution of technology has often driven new audio tools and effects, from early architectural acoustics through electromechanical and electronic devices to the digitisation of music production studios. Throughout time, music has constantly borrowed ideas and technological advancements from all other fields and contributed back to the innovative technology. This is defined as transsectorial innovation and fundamentally underpins the technological developments of audio effects. The development and evolution of audio effect technology is discussed, highlighting major technical breakthroughs and the impact of available audio effects

Design, planning, deployment and operation of a learning platform

This paper explores in depth the effective management of Odoo-based systems in educational and business environments, with a special focus on the experience of the aUPaEU educational project. Odoo, an open source business management system, has proven to be an essential tool for managing a wide range of business processes. Successful implementation of Odoo involves sound management and appropriate approaches to critical issues such as backup, version migration and continuous monitoring. This paper presents a comprehensive methodology that addresses these fundamental aspects of Odoo system administration. For backups, it proposes the use of Minio, a scalable cloud storage solution that ensures the integrity of enterprise data. Version migration is addressed through the use of OpenUpgrade, a tool that automates this complex process and minimises the associated risks. In terms of system monitoring, a set of tools including Prometheus, Grafana and Loki are used, enabling constant and effective control of the Odoo infrastructure. In the context of aUPaEU, this paper also examines how these solutions and best practices are specifically applied to the management of Odoo systems in education. It highlights how the aUPaEU has used these tools to improve the efficiency and reliability of its systems, resulting in a more robust user experience and more effective management of educational resources. The paper not only presents these tools, but also highlights best practices for their successful implementation in the Odoo environment, with a focus on how these practices benefit the aUPaEU. In addition, future directions are explored to further improve Odoo systems management and its impact on the aUPaEU, making it a valuable resource for both working professionals and students venturing into this ever-evolving field. Ultimately, this work makes a significant contribution to the field of Odoo systems management by providing comprehensive guidance and essential tools that respond to the evolving needs of companies and organisations using Odoo to drive their business operations, including educational cases such as aUPaEU

A Systematic Review of the Criminogenic Potential of Synthetic Biology and Routes to Future Crime Prevention

Synthetic biology has the potential to positively transform society in many application areas, including medicine. In common with all revolutionary new technologies, synthetic biology can also enable crime. Like cybercrime, that emerged following the advent of the internet, biocrime can have a significant effect on society, but may also impact on peoples' health. For example, the scale of harm caused by the SARS-CoV-2 pandemic illustrates the potential impact of future biocrime and highlights the need for prevention strategies. Systematic evidence quantifying the crime opportunities posed by synthetic biology has to date been very limited. Here, we systematically reviewed forms of crime that could be facilitated by synthetic biology with a view to informing their prevention. A total of 794 articles from four databases were extracted and a three-step screening phase resulted in 15 studies that met our threshold criterion for thematic synthesis. Within those studies, 13 exploits were identified. Of these, 46% were dependent on technologies characteristic of synthetic biology. Eight potential crime types emerged from the studies: bio-discrimination, cyber-biocrime, bio-malware, biohacking, at-home drug manufacturing, illegal gene editing, genetic blackmail, and neuro-hacking. 14 offender types were identified. For the most commonly identified offenders (>3 mentions) 40% were outsider threats. These observations suggest that synthetic biology presents substantial new offending opportunities. Moreover, that more effective engagement, such as ethical hacking, is needed now to prevent a crime harvest from developing in the future. A framework to address the synthetic biology crime landscape is proposed

From data to marine ecosystem assessments of the Southern Ocean: Achievements, challenges, and lessons for the future

Southern Ocean ecosystems offer numerous benefits to human society and the global environment, and maintaining them requires well-informed and effective ecosystem-based management. Up to date and accurate information is needed on the status of species, communities, habitats and ecosystems and the impacts of fisheries, tourism and climate change. This information can be used to generate indicators and undertake assessments to advise decision-makers. Currently, most marine assessments are derivative: reliant on the review of published peer-reviewed literature. More timely and accurate information for decision making requires an integrated Marine Biological Observing and Informatics System that combines and distributes data. For such a system to work, data needs to be shared according to the FAIR principles (Findable, Accessible, Interoperable, and Reusable), use transparent and reproducible science, adhere to the principle of action ecology and complement global initiatives. Here we aim to provide an overview of the components of such a system currently in place for the Southern Ocean, the existing gaps and a framework for a way forward

Roadmap on multiscale materials modeling

Modeling and simulation is transforming modern materials science, becoming an important tool for the discovery of new materials and material phenomena, for gaining insight into the processes that govern materials behavior, and, increasingly, for quantitative predictions that can be used as part of a design tool in full partnership with experimental synthesis and characterization. Modeling and simulation is the essential bridge from good science to good engineering, spanning from fundamental understanding of materials behavior to deliberate design of new materials technologies leveraging new properties and processes. This Roadmap presents a broad overview of the extensive impact computational modeling has had in materials science in the past few decades, and offers focused perspectives on where the path forward lies as this rapidly expanding field evolves to meet the challenges of the next few decades. The Roadmap offers perspectives on advances within disciplines as diverse as phase field methods to model mesoscale behavior and molecular dynamics methods to deduce the fundamental atomic-scale dynamical processes governing materials response, to the challenges involved in the interdisciplinary research that tackles complex materials problems where the governing phenomena span different scales of materials behavior requiring multiscale approaches. The shift from understanding fundamental materials behavior to development of quantitative approaches to explain and predict experimental observations requires advances in the methods and practice in simulations for reproducibility and reliability, and interacting with a computational ecosystem that integrates new theory development, innovative applications, and an increasingly integrated software and computational infrastructure that takes advantage of the increasingly powerful computational methods and computing hardware

Policies for Web Services

Web services are predominantly used to implement service-oriented architectures (SOA). However, there are several areas such as temporal dimensions, real-time, streaming, or efficient and flexible file transfers where web service functionality should be extended. These extensions can, for example, be achieved by using policies. Since there are often alternative solutions to provide functionality (e.g., different protocols can be used to achieve the transfer of data), the WS-Policy standard is especially useful to extend web services with policies. It allows to create policies to generally state the properties under which a service is provided and to explicitly express alternative properties. To extend the functionality of web services, two policies are introduced in this thesis: the Temporal Policy and the Communication Policy. The temporal policy is the foundation for adding temporal dimensions to a WS-Policy. The temporal policy itself is not a WS-Policy but an independent policy language that describes temporal dimensions of and dependencies between temporal policies and WS-Policies. Switching of protocol dependencies, pricing of services, quality of service, and security are example areas for using a temporal policy. To describe protocol dependencies of a service for streaming, real-time and file transfers, a communication policy can be utilized. The communication policy is a concrete WS-Policy. With the communication policy, a service can expose the protocols it depends on for a communication after its invocation. Thus, a web service client knows the protocols required to support a communication with the service. Therefore, it is possible to evaluate beforehand whether an invocation of a service is reasonable. On top of the newly introduced policies, novel mechanisms and tools are provided to alleviate service use and enable flexible and efficient data handling. Furthermore, the involvement of the end user in the development process can be achieved more easily. The Flex-SwA architecture, the first component in this thesis based on the newly introduced policies, implements the actual file transfers and streaming protocols that are described as dependencies in a communication policy. Several communication patterns support the flexible handling of the communication. A reference concept enables seamless message forwarding with reduced data movement. Based on the Flex-SwA implementation and the communication policy, it is possible to improve usability - especially in the area of service-oriented Grids - by integrating data transfers into an automatically generated web and Grid service client. The Web and Grid Service Browser is introduced in this thesis as such a generic client. It provides a familiar environment for using services by offering the client generation as part of the browser. Data transfers are directly integrated into service invocation without having to perform data transmissions explicitly. For multimedia MIME types, special plugins allow the consumption of multimedia data. To enable an end user to build applications that also leverage high performance computing resources, the Service-enabled Mashup Editor is presented that lets the user combine popular web applications with web and Grid services. Again, the communication policy provides descriptive means for file transfers and Flex-SwAs reference concept is used for data exchange. To show the applicability of these novel concepts, several use cases from the area of multimedia processing have been selected. Based on the temporal policy, the communication policy, Flex-SwA, the Web and Grid Service Browser, and the Service-enabled Mashup Editor, the development of a scalable service-oriented multimedia architecture is presented. The multimedia SOA offers, among others, a face detection workflow, a video-on-demand service, and an audio resynthesis service. More precisely, a video-on-demand service describes its dependency on a multicast protocol by using a communication policy. A temporal policy is then used to perform the description of a protocol switch from one multicast protocol to another one by changing the communication policy at the end of its validity period. The Service-enabled Mashup Editor is used as a client for the new multicast protocol after the multicast protocol has been switched. To stream single frames from a frame decoder service to a face detection service (which are both part of the face detection workflow) and to transfer audio files with the different Flex-SwA communication patterns to an audio resynthesis service, Flex-SwA is used. The invocation of the face detection workflow and the audio resynthesis service is realized with the Web and Grid Service Browser

Validation of high throughput sequencing and microbial forensics applications

High throughput sequencing (HTS) generates large amounts of high quality sequence data for microbial genomics. The value of HTS for microbial forensics is the speed at which evidence can be collected and the power to characterize microbial-related evidence to solve biocrimes and bioterrorist events. As HTS technologies continue to improve, they provide increasingly powerful sets of tools to support the entire field of microbial forensics. Accurate, credible results allow analysis and interpretation, significantly influencing the course and/or focus of an investigation, and can impact the response of the government to an attack having individual, political, economic or military consequences. Interpretation of the results of microbial forensic analyses relies on understanding the performance and limitations of HTS methods, including analytical processes, assays and data interpretation. The utility of HTS must be defined carefully within established operating conditions and tolerances. Validation is essential in the development and implementation of microbial forensics methods used for formulating investigative leads attribution. HTS strategies vary, requiring guiding principles for HTS system validation. Three initial aspects of HTS, irrespective of chemistry, instrumentation or software are: 1) sample preparation, 2) sequencing, and 3) data analysis. Criteria that should be considered for HTS validation for microbial forensics are presented here. Validation should be defined in terms of specific application and the criteria described here comprise a foundation for investigators to establish, validate and implement HTS as a tool in microbial forensics, enhancing public safety and national security.Peer reviewe