Analysis, design and experimental evaluation of connectivity management in heterogeneous wireless environments

Mención Internacional en el título de doctorThe future of network communications is mobile as many more users demand for ubiquitous connectivity. Wireless has become the primary access technology or even the only one, leading to an explosion in traffic demand. This challenges network providers to manage and configure new requirements without incrementing costs in the same amount. In addition to the growth in the use of mobile devices, there is a need to operate simultaneously different access technologies. As well, the great diversity of applications and the capabilities of mobile terminals makes possible for us to live in a hyper-connected world and offers new scenarios. This heterogeneity poses great challenges that need to be addressed to offer better performance and seamless experience to the final user. We need to orchestrate solutions to increase flexibility and empower interoperability. Connectivity management is handled from different angles. In the network stack, mobility is more easily handled by IP mobility protocols, since IP is the common layer between the different access technologies and the application diversity. From the end-user perspective, the connection manager is in charge of handling connectivity issues in mobile devices, but it is an unstandardized entity so its performance is heavily implementation-dependent. In this thesis we explore connectivity management from different angles. We study mobility protocols as they are part of our proposed solutions. In most of the cases we include an experimental evaluation of performance with 3G and IEEE 802.11 as the main technologies. We consider heterogeneous scenarios, with several access technologies where mobile devices have also several network interfaces. We evaluate how connectivity is handled as well as its influence in a handover. Based on the analysis of real traces from a cellular network, we confirm the suitability of more efficient mobility management. Moreover, we propose and evaluate three different solutions for providing mobility support in three different heterogeneous scenarios. We perform an experimental evaluation of a vehicular route optimization for network mobility, reporting on the challenges and lessons learned in such a complicated networking environment. We propose an architecture for supporting mobility and enhance handover in a passive optical network deployment. In addition, we design and deploy a mechanism for mobility management based on software-defined networking.Programa Oficial de Doctorado en Ingeniería TelemáticaPresidente: Arturo Azcorra Saloña.- Secretario: Ramón Agüero Calvo.- Vocal: Daniel Nunes Coruj

Descentralização da gestão da mobilidade IP nas redes do futuro

Doutoramento em Engenharia ElectrotécnicaThe massive adoption of sophisticated mobile devices and applications led to the increase of mobile data in the last decade, which it is expected to continue. This increase of mobile data negatively impacts the network planning and dimension, since core networks are heavy centralized. Mobile operators are investigating atten network architectures that distribute the responsibility of providing connectivity and mobility, in order to improve the network scalability and performance. Moreover, service providers are moving the content servers closer to the user, in order to ensure high availability and performance of content delivery. Besides the e orts to overcome the explosion of mobile data, current mobility management models are heavy centralized to ensure reachability and session continuity to the users connected to the network. Nowadays, deployed architectures have a small number of centralized mobility anchors managing the mobile data and the mobility context of millions of users, which introduces issues related to performance and scalability that require costly network mechanisms. The mobility management needs to be rethought out-of-the box to cope with atten network architectures and distributed content servers closer to the user, which is the purpose of the work developed in this Thesis. The Thesis starts with a characterization of mobility management into well-de ned functional blocks, their interaction and potential grouping. The decentralized mobility management is studied through analytical models and simulations, in which di erent mobility approaches distinctly distribute the mobility management functionalities through the network. The outcome of this study showed that decentralized mobility management brings advantages. Hence, it was proposed a novel distributed and dynamic mobility management approach, which is exhaustively evaluated through analytical models, simulations and testbed experiments. The proposed approach is also integrated with seamless horizontal handover mechanisms, as well as evaluated in vehicular environments. The mobility mechanisms are also speci ed for multihomed scenarios, in order to provide data o oading with IP mobility from cellular to other access networks. In the pursuing of the optimized mobile routing path, a novel network-based strategy for localized mobility is addressed, in which a replication binding system is deployed in the mobility anchors distributed through the access routers and gateways. Finally, we go further in the mobility anchoring subject, presenting a context-aware adaptive IP mobility anchoring model that dynamically assigns the mobility anchors that provide the optimized routing path to a session, based on the user and network context. The integration of dynamic and distributed concepts in the mobility management, such as context-aware adaptive mobility anchoring and dynamic mobility support, allow the optimization of network resources and the improvement of user experience. The overall outcome demonstrates that decentralized mobility management is a promising direction, hence, its ideas should be taken into account by mobile operators in the deployment of future networks.Na última década verificou-se uma massificação dos dispositivos móveis e das suas aplicações, o que tem vindo a aumentar o consumo de dados móveis. Este aumento dificulta o planeamento e dimensionamento das redes devido principalmente aos modelos extremamente centralizados adoptados por estas. Os operadores móveis têm vindo a estudar modelos mais até para as redes, os quais distribuem a responsabilidade de fornecer conectividade e mobilidade, no sentido de melhorar a escalabilidade e desempenho da rede. Além disso, de forma a garantir um desempenho elevado na entrega dos conteúdos, os fornecedores de serviço têm vindo a mover os servidores de conteúdos para locais mais próximos do utilizador. Apesar do esforço na procura de soluções para o crescente consumo de dados móveis, os modelos atuais de gestão de mobilidade são demasiado centralizados para conseguir assegurar a continuidade de sessão aos utilizadores conectados à rede. As arquiteturas implementadas têm um número muito reduzido de âncoras móveis centralizadas que gerem todos os dados móveis e a informação de contexto da mobilidade, o que leva a uma diminuição de desempenho e escalabilidade, solucionadas através de mecanismos de rede dispendiosos. A gestão da mobilidade precisa de ser repensada de forma a poder lidar com arquiteturas de rede até com a distribuição dos servidores de conteúdos para nós mais próximos dos utilizadores, que é o objectivo principal da Tese apresentada. Primeiro, é apresentada a caracterização da gestão de mobilidade em blocos funcionais, a interação entre eles e potenciais agrupamentos dos mesmos. A gestão da mobilidade descentralizada é estudada através de modelos analíticos e simulações, em que diferentes abordagens distribuem as funcionalidades da mobilidade pela rede. Como resultado deste estudo verificou-se que a descentralização da mobilidade traz vantagens claras. Com base nestes resultados foi proposta uma nova abordagem de gestão de mobilidade distribuída e dinâmica, que é exaustivamente avaliada através de modelos analíticos, simulações e experiências numa bancada de testes. A abordagem proposta é também integrada com mecanismos de handovers horizontais transparentes, assim como é avaliada em ambientes veiculares. Os mecanismos de mobilidade da abordagem proposta são também especificados para cenários de multihoming, de forma a proporcionar o offloading de dados com suporte de mobilidade das redes celulares para outras redes de acesso. Com o objectivo de optimizar o encaminhamento de dados móveis, foi criada uma nova estratégia para o suporte da mobilidade localizada, em que um sistema de replicação de bindings é integrado nas âncoras de mobilidade distribuídas através dos routers de acesso e dos gateways. Finalmente apresenta-se um modelo de ancoramento adaptativo para a mobilidade com base em contexto, o qual dinamicamente determina as âncoras de mobilidade que oferecem a melhor rota para uma dada sessão, baseado na informação do utilizador e da rede. A integração de conceitos de dinamismo e de distribuição na gestão da mobilidade, como o ancoramento adaptativo e o suporte dinâmico da mobilidade, permitem a optimização dos recursos da rede e uma melhor experiência por parte do utilizador. Os resultados demonstram, de uma forma geral, que a gestão descentralizada da mobilidade é um caminho promissor, logo este deve ser tomado em consideração pelas operadoras móveis aquando do desenvolvimento das redes do futuro

IP Mobility in Wireless Operator Networks

Wireless network access is gaining increased heterogeneity in terms of the types of IP capable access technologies. The access network heterogeneity is an outcome of incremental and evolutionary approach of building new infrastructure. The recent success of multi-radio terminals drives both building a new infrastructure and implicit deployment of heterogeneous access networks. Typically there is no economical reason to replace the existing infrastructure when building a new one. The gradual migration phase usually takes several years. IP-based mobility across different access networks may involve both horizontal and vertical handovers. Depending on the networking environment, the mobile terminal may be attached to the network through multiple access technologies. Consequently, the terminal may send and receive packets through multiple networks simultaneously. This dissertation addresses the introduction of IP Mobility paradigm into the existing mobile operator network infrastructure that have not originally been designed for multi-access and IP Mobility. We propose a model for the future wireless networking and roaming architecture that does not require revolutionary technology changes and can be deployed without unnecessary complexity. The model proposes a clear separation of operator roles: (i) access operator, (ii) service operator, and (iii) inter-connection and roaming provider. The separation allows each type of an operator to have their own development path and business models without artificial bindings with each other. We also propose minimum requirements for the new model. We present the state of the art of IP Mobility. We also present results of standardization efforts in IP-based wireless architectures. Finally, we present experimentation results of IP-level mobility in various wireless operator deployments.Erilaiset langattomat verkkoyhteydet lisääntyvät Internet-kykyisten teknologioiden muodossa. Lukuisten eri teknologioiden päällekkäinen käyttö johtuu vähitellen ja tarpeen mukaan rakennetusta verkkoinfrastruktuurista. Useita radioteknologioita (kuten WLAN, GSM ja UMTS) sisältävien päätelaitteiden (kuten älypuhelimet ja kannettavat tietokoneet) viimeaikainen kaupallinen menestys edesauttaa uuden verkkoinfrastruktuurin rakentamista, sekä mahdollisesti johtaa verkkoteknologioiden kirjon lisääntymiseen. Olemassa olevaa verkkoinfrastruktuuria ei kaupallisista syistä kannata korvata uudella teknologialla yhdellä kertaa, vaan vaiheittainen siirtymävaihe kestää tyypillisesti useita vuosia. Internet-kykyiset päätelaitteet voivat liikkua joko saman verkkoteknologian sisällä tai eri verkkoteknologioiden välillä. Verkkoympäristöstä riippuen liikkuvat päätelaitteet voivat liittyä verkkoon useiden verkkoyhteyksien kautta. Näin ollen päätelaite voi lähettää ja vastaanottaa tietoliikennepaketteja yhtäaikaisesti lukuisia verkkoja pitkin. Tämä väitöskirja käsittelee Internet-teknologioiden liikkuvuutta ja näiden teknologioiden tuomista olemassa oleviin langattomien verkko-operaattorien verkkoinfrastruktuureihin. Käsiteltäviä verkkoinfrastruktuureita ei alun perin ole suunniteltu Internet-teknologian liikkuvuuden ja monien yhtäaikaisten yhteyksien ehdoilla. Tässä työssä ehdotetaan tulevaisuuden langattomien verkkojen arkkitehtuurimallia ja ratkaisuja verkkovierailujen toteuttamiseksi. Ehdotettu arkkitehtuuri voidaan toteuttaa ilman mittavia teknologisia mullistuksia. Mallin mukaisessa ehdotuksessa verkko-operaattorin roolit jaetaan selkeästi (i) verkko-operaattoriin, (ii) palveluoperaattoriin ja (iii) yhteys- sekä verkkovierailuoperaattoriin. Roolijako mahdollistaa sen, että kukin operaattorityyppi voi kehittyä itsenäisesti, ja että teennäiset verkkoteknologiasidonnaisuudet poistuvat palveluiden tuottamisessa. Työssä esitetään myös alustava vaatimuslista ehdotetulle mallille, esimerkiksi yhteysoperaattorien laatuvaatimukset. Väitöskirja esittelee myös liikkuvien Internet-teknologioiden viimeisimmän kehityksen. Työssä näytetään lisäksi standardointituloksia Internet-kykyisissä langattomissa arkkitehtuureissa

Microbial Secondary Metabolites and Biotechnology

Many research teams are working to demonstrate that microorganisms can be our daily partners, due to the great diversity of biochemical transformations and molecules they are able to produce. This Special Issue highlights several facets of the production of microbial metabolites of interest. From the discovery of new strains or new bioactive molecules issued from novel environments, to the increase in their synthesis by traditional or innovative methods, different levels of biotechnological processes are addressed. Combining the new dimensions of "Omics" sciences, such as genomics, transcriptomics or metabolomics, microbial biotechnologies are opening up incredible opportunities for discovering and improving microorganisms and their production

Data ethics : building trust : how digital technologies can serve humanity

Data is the magic word of the 21st century. As oil in the 20th century and electricity in the 19th century: For citizens, data means support in daily life in almost all activities, from watch to laptop, from kitchen to car, from mobile phone to politics. For business and politics, data means power, dominance, winning the race. Data can be used for good and bad, for services and hacking, for medicine and arms race. How can we build trust in this complex and ambiguous data world? How can digital technologies serve humanity? The 45 articles in this book represent a broad range of ethical reflections and recommendations in eight sections: a) Values, Trust and Law, b) AI, Robots and Humans, c) Health and Neuroscience, d) Religions for Digital Justice, e) Farming, Business, Finance, f) Security, War, Peace, g) Data Governance, Geopolitics, h) Media, Education, Communication. The authors and institutions come from all continents. The book serves as reading material for teachers, students, policy makers, politicians, business, hospitals, NGOs and religious organisations alike. It is an invitation for dialogue, debate and building trust! The book is a continuation of the volume “Cyber Ethics 4.0” published in 2018 by the same editors

Preclinical Evaluation of Lipid-Based Nanosystems

The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC)), nanoemulsions, and liposomes, among others, is widespread. Several researchers have described the advantages of different applications of these nanosystems. For instance, they can increase the targeting and bioavailability of drugs, improving therapeutic effects. Their use in the cosmetic field is also promising, owing to their moisturizing properties and ability to protect labile cosmetic actives. Thus, it is surprising that only a few lipid-based nanosystems have reached the market. This can be explained by the strict regulatory requirements of medicines and the occurrence of unexpected in vivo failure, which highlights the need to conduct more preclinical studies.Current research is focused on testing the in vitro, ex vivo, and in vivo efficacy of lipid-based nanosystems to predict their clinical performance. However, there is a lack of method validation, which compromises the comparison between different studies.This book brings together the latest research and reviews that report on in vitro, ex vivo, and in vivo preclinical studies using lipid-based nanosystems. Readers can find up-to-date information on the most common experiments performed to predict the clinical behavior of lipid-based nanosystems. A series of 15 research articles and a review are presented, with authors from 15 different countries, which demonstrates the universality of the investigations that have been carried out in this area

Foundations of Software Science and Computation Structures

This open access book constitutes the proceedings of the 25th International Conference on Foundations of Software Science and Computational Structures, FOSSACS 2022, which was held during April 4-6, 2022, in Munich, Germany, as part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2022. The 23 regular papers presented in this volume were carefully reviewed and selected from 77 submissions. They deal with research on theories and methods to support the analysis, integration, synthesis, transformation, and verification of programs and software systems

Foundations of Software Science and Computation Structures

This open access book constitutes the proceedings of the 25th International Conference on Foundations of Software Science and Computational Structures, FOSSACS 2022, which was held during April 4-6, 2022, in Munich, Germany, as part of the European Joint Conferences on Theory and Practice of Software, ETAPS 2022. The 23 regular papers presented in this volume were carefully reviewed and selected from 77 submissions. They deal with research on theories and methods to support the analysis, integration, synthesis, transformation, and verification of programs and software systems