Achieving the Way for Automated Segmentation of Nuclei in Cancer Tissue Images through Morphology-Based Approach: a Quantitative Evaluation

In this paper we address the problem of nuclear segmentation in cancer tissue images, that is critical for specific protein activity quantification and for cancer diagnosis and therapy. We present a fully automated morphology-based technique able to perform accurate nuclear segmentations in images with heterogeneous staining and multiple tissue layers and we compare it with an alternate semi-automated method based on a well established segmentation approach, namely active contours. We discuss active contours’ limitations in the segmentation of immunohistochemical images and we demonstrate and motivate through extensive experiments the better accuracy of our fully automated approach compared to various active contours implementations

Object Modelling and Tracking in Videos via Multidimensional Features

We propose to model a tracked object in a video sequence by locating a list of object features that are ranked according to their ability to differentiate against the image background. The Bayesian inference is utilised to derive the probabilistic location of the object in the current frame, with the prior being approximated from the previous frame and the posterior achieved via the current pixel distribution of the object. Consideration has also been made to a number of relevant aspects of object tracking including multidimensional features and the mixture of colours, textures, and object motion. The experiment of the proposed method on the video sequences has been conducted and has shown its effectiveness in capturing the target in a moving background and with nonrigid object motion