19,722 research outputs found
The London Creative Industries
This lecture draws from the Creative Industries Observatory research on the London creative industries and in particular provides some initial insights into the networks and relationships which exist including organisational structure, size, and location. Consideration has been given to clustering and markets. In particular attention has been paid to the levels of creativity found in the London creative industries and the possible implications for public policy intervention. These findings are based on a shared definitional framework, and can be compared with other cities
Assessing architectural evolution: A case study
This is the post-print version of the Article. The official published can be accessed from the link below - Copyright @ 2011 SpringerThis paper proposes to use a historical perspective on generic laws, principles,
and guidelines, like Lehman’s software evolution laws and Martin’s design principles, in order to achieve a multi-faceted process and structural assessment of a system’s architectural evolution. We present a simple structural model with associated historical metrics and
visualizations that could form part of an architect’s dashboard. We perform such an assessment for the Eclipse SDK, as a case study of a large, complex, and long-lived system for which sustained effective architectural evolution is paramount. The twofold aim of checking generic principles on a well-know system is, on the one hand,
to see whether there are certain lessons that could be learned for best practice of architectural evolution, and on the other hand to get more insights about the applicability of such principles. We find that while the Eclipse SDK does follow several of the laws and principles, there are some deviations, and we discuss areas of architectural improvement and limitations of the assessment approach
A New Quartet Tree Heuristic for Hierarchical Clustering
We consider the problem of constructing an an optimal-weight tree from the
3*(n choose 4) weighted quartet topologies on n objects, where optimality means
that the summed weight of the embedded quartet topologiesis optimal (so it can
be the case that the optimal tree embeds all quartets as non-optimal
topologies). We present a heuristic for reconstructing the optimal-weight tree,
and a canonical manner to derive the quartet-topology weights from a given
distance matrix. The method repeatedly transforms a bifurcating tree, with all
objects involved as leaves, achieving a monotonic approximation to the exact
single globally optimal tree. This contrasts to other heuristic search methods
from biological phylogeny, like DNAML or quartet puzzling, which, repeatedly,
incrementally construct a solution from a random order of objects, and
subsequently add agreement values.Comment: 22 pages, 14 figure
WFPC2 Observations of Compact Star Cluster Nuclei in Low Luminosity Spiral Galaxies
We have used the Wide Field Planetary Camera 2 aboard the Hubble Space
Telescope to image the compact star cluster nuclei of the nearby, late-type,
low-luminosity spiral galaxies NGC 4395, NGC 4242, and ESO 359-029. We also
analyze archival WFPC2 observations of the compact star cluster nucleus of M33.
A comparative analysis of the structural and photometric properties of these
four nuclei is presented. All of the nuclei are very compact, with luminosity
densities increasing at small radii to the resolution limit of our data. NGC
4395 contains a Seyfert 1 nucleus with a distinct bipolar structure and bright
associated filaments which are likely due to [OIII] emission. The M33 nucleus
has a complex structure, with elongated isophotes and possible signatures of
weak activity, including a jet-like component. The other two nuclei are not
known to be active, but share similar physical size scales and luminosities to
the M33 and NGC 4395 nuclei. The circumnuclear environments of all four of our
program galaxies are extremely diffuse, have only low-to-moderate star
formation, and appear to be devoid of large quantities of dust. The central
gravitational potentials of the galaxies are also quite shallow, making the
origin of these types of `naked' nuclei problematic.Comment: to appear in the July 1999 Astronomical Journal; 38 pages (Latex), 5
tables (postscript), 21 figures (gif); postscript versions of the figures may
be obtained via anonymous ftp at
ftp://ftp.cv.nrao.edu/NRAO-staff/lmatthew/lanl-nucle
An Empirical Study of Cohesion and Coupling: Balancing Optimisation and Disruption
Search based software engineering has been extensively applied to the problem of finding improved modular structures that maximise cohesion and minimise coupling. However, there has, hitherto, been no longitudinal study of developers’ implementations, over a series of sequential releases. Moreover, results validating whether developers respect the fitness functions are scarce, and the potentially disruptive effect of search-based remodularisation is usually overlooked. We present an empirical study of 233 sequential releases of 10 different systems; the largest empirical study reported in the literature so far, and the first longitudinal study. Our results provide evidence that developers do, indeed, respect the fitness functions used to optimise cohesion/coupling (they are statistically significantly better than arbitrary choices with p << 0.01), yet they also leave considerable room for further improvement (cohesion/coupling can be improved by 25% on average). However, we also report that optimising the structure is highly disruptive (on average more than 57% of the structure must change), while our results reveal that developers tend to avoid such disruption. Therefore, we introduce and evaluate a multi-objective evolutionary approach that minimises disruption while maximising cohesion/coupling improvement. This allows developers to balance reticence to disrupt existing modular structure, against their competing need to improve cohesion and coupling. The multi-objective approach is able to find modular structures that improve the cohesion of developers’ implementations by 22.52%, while causing an acceptably low level of disruption (within that already tolerated by developers)
The \u2018KIBS engine\u2019 of Regional Innovation Systems: empirical evidence from European regions
Knowledge-intensive business services (KIBS) are key players in innovation systems, particularly in advanced regions where manufacturing competitiveness largely depends on knowledge contents provided by highly specialized suppliers. This paper investigates the relationship between KIBS and the structure and performance of regional innovation systems in Europe. It maps the co-evolution between KIBS and manufacturing in European regions, identifying emergent typologies of regional innovation systems. Results show that KIBS are a defining element of innovation-oriented regions, whereas their scarcity and slow growth distinctively characterize poor performing innovation systems. However, the analysis also identifies a set of core manufacturing regions in Europe, which are evolving along a different trajectory into knowledge-oriented service-manufacturing complexes
The role of viral genomics in understanding COVID-19 outbreaks in long-term care facilities
We reviewed all genomic epidemiology studies on COVID-19 in long-term care facilities (LTCFs) that had been published to date. We found that staff and residents were usually infected with identical, or near identical, SARS-CoV-2 genomes. Outbreaks usually involved one predominant cluster, and the same lineages persisted in LTCFs despite infection control measures. Outbreaks were most commonly due to single or few introductions followed by a spread rather than a series of seeding events from the community into LTCFs. The sequencing of samples taken consecutively from the same individuals at the same facilities showed the persistence of the same genome sequence, indicating that the sequencing technique was robust over time. When combined with local epidemiology, genomics allowed probable transmission sources to be better characterised. The transmission between LTCFs was detected in multiple studies. The mortality rate among residents was high in all facilities, regardless of the lineage. Bioinformatics methods were inadequate in a third of the studies reviewed, and reproducing the analyses was difficult because sequencing data were not available in many facilities
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