Inertial sensor-based knee flexion/extension angle estimation

A new method for estimating knee joint flexion/extension angles from segment acceleration and angular velocity data is described. The approach uses a combination of Kalman filters and biomechanical constraints based on anatomical knowledge. In contrast to many recently published methods, the proposed approach does not make use of the earth’s magnetic field and hence is insensitive to the complex field distortions commonly found in modern buildings. The method was validated experimentally by calculating knee angle from measurements taken from two IMUs placed on adjacent body segments. In contrast to many previous studies which have validated their approach during relatively slow activities or over short durations, the performance of the algorithm was evaluated during both walking and running over 5 minute periods. Seven healthy subjects were tested at various speeds from 1 to 5 miles/hour. Errors were estimated by comparing the results against data obtained simultaneously from a 10 camera motion tracking system (Qualysis). The average measurement error ranged from 0.7 degrees for slow walking (1 mph) to 3.4 degrees for running (5mph). The joint constraint used in the IMU analysis was derived from the Qualysis data. Limitations of the method, its clinical application and its possible extension are discussed

Mobile Quantification and Therapy Course Tracking for Gait Rehabilitation

This paper presents a novel autonomous quality metric to quantify the rehabilitations progress of subjects with knee/hip operations. The presented method supports digital analysis of human gait patterns using smartphones. The algorithm related to the autonomous metric utilizes calibrated acceleration, gyroscope and magnetometer signals from seven Inertial Measurement Unit attached on the lower body in order to classify and generate the grading system values. The developed Android application connects the seven Inertial Measurement Units via Bluetooth and performs the data acquisition and processing in real-time. In total nine features per acceleration direction and lower body joint angle are calculated and extracted in real-time to achieve a fast feedback to the user. We compare the classification accuracy and quantification capabilities of Linear Discriminant Analysis, Principal Component Analysis and Naive Bayes algorithms. The presented system is able to classify patients and control subjects with an accuracy of up to 100\%. The outcomes can be saved on the device or transmitted to treating physicians for later control of the subject's improvements and the efficiency of physiotherapy treatments in motor rehabilitation. The proposed autonomous quality metric solution bears great potential to be used and deployed to support digital healthcare and therapy.Comment: 5 Page

Robust localization with wearable sensors

Measuring physical movements of humans and understanding human behaviour is useful in a variety of areas and disciplines. Human inertial tracking is a method that can be leveraged for monitoring complex actions that emerge from interactions between human actors and their environment. An accurate estimation of motion trajectories can support new approaches to pedestrian navigation, emergency rescue, athlete management, and medicine. However, tracking with wearable inertial sensors has several problems that need to be overcome, such as the low accuracy of consumer-grade inertial measurement units (IMUs), the error accumulation problem in long-term tracking, and the artefacts generated by movements that are less common. This thesis focusses on measuring human movements with wearable head-mounted sensors to accurately estimate the physical location of a person over time. The research consisted of (i) providing an overview of the current state of research for inertial tracking with wearable sensors, (ii) investigating the performance of new tracking algorithms that combine sensor fusion and data-driven machine learning, (iii) eliminating the effect of random head motion during tracking, (iv) creating robust long-term tracking systems with a Bayesian neural network and sequential Monte Carlo method, and (v) verifying that the system can be applied with changing modes of behaviour, defined as natural transitions from walking to running and vice versa. This research introduces a new system for inertial tracking with head-mounted sensors (which can be placed in, e.g. helmets, caps, or glasses). This technology can be used for long-term positional tracking to explore complex behaviours

Moving On:Measuring Movement Remotely after Stroke

Most persons with stroke suffer from motor impairment, which restricts mobility on one side, and affects their independence in daily life activities. Measuring recovery is needed to develop individualized therapies. However, commonly used clinical outcomes suffer from low resolution and subjectivity. Therefore, objective biomechanical metrics should be identified to measure movement quality. However, non-portable laboratory setups are required in order to measure these metrics accurately. Alternatively, minimal wearable systems can be developed to simplify measurements performed at clinic or home to monitor recovery. Thus, the goal of the thesis was ‘To identify metrics that reflect movement quality of upper and lower extremities after stroke and develop wearable minimal systems for tracking the proposed metrics’. Section Upper Extremity First, we systematically reviewed literature ( Chapter II ) to identify metrics used to measure reaching recovery longitudinally post-stroke. Although several metrics were found, it was not clear how they differentiated recovery from compensation strategies. Future studies must address this gap in order to optimize stroke therapy. Next, we assessed a ‘valid’ measure for smoothness of upper paretic limb reaching ( Chapter III ), as this was commonly used to measure movement quality. After a systematic review and simulation analyses, we found that reaching smoothness is best measured using spectral arc length. The studies in this section offer us a better understanding of movement recovery in the upper extremity post-stroke. Section Lower Extremity Although metrics that reflect gait recovery are yet to be identified, in this section we focused on developing minimal solutions to measure gait quality. First, we showed the feasibility of 1D pressure insoles as a lightweight alternative for measuring 3D Ground Reaction Forces (GRF) ( Chapter IV ). In the following chapters, we developed a minimal system; the Portable Gait Lab (PGL) using only three Inertial Measurement Units (IMUs) (one per foot and one on the pelvis). We explored the Centroidal Moment Pivot (CMP) point ( Chapter V ) as a biomechanical constraint that can help with the reduction in sensors. Then, we showed the feasibility of the PGL to track 3D GRF ( Chapters VI-VII ) and relative foot and CoM kinematics ( Chapter VIII-IX ) during variable overground walking by healthy participants. Finally, we performed a limited validation study in persons with chronic stroke ( Chapter X ). This thesis offers knowledge and tools which can help clinicians and researchers understand movement quality and thereby develop individualized therapies post-stroke

Gait Modeling Using Genetic Algorithm Optimized Four-Bar Linkages

Important in diagnosing gait abnormalities and pathologies is knowing the position of the leg at various points throughout the gait cycle. This is currently done with motion capture technology but the demand for Inertial Measurement Unit (IMU) based navigation and position tracking has been on the rise. A required component of this alternative is a gait model that can accurately predict the position of points of interest. In this thesis, a Kalman Filter is constructed using a contrived model to test if, given an accurate gait model, the filter can converge to an accurate and true position solution. Also presented is a Genetic Algorithm approach to dynamic system modeling. The dynamic system is made up of a four-bar linkage and has the ability to adapt to different gaits, both healthy and pathological. Results for the Kalman Filter are illustrated through convergence plots, and final position solutions and results for the Genetic Algorithm are given by position solutions of the four-bar linkage. These results show that a genetic approach is robust and has application in gait analysi

Adaptive Indoor Pedestrian Tracking Using Foot-Mounted Miniature Inertial Sensor

This dissertation introduces a positioning system for measuring and tracking the momentary location of a pedestrian, regardless of the environmental variations. This report proposed a 6-DOF (degrees of freedom) foot-mounted miniature inertial sensor for indoor localization which has been tested with simulated and real-world data. To estimate the orientation, velocity and position of a pedestrian we describe and implement a Kalman filter (KF) based framework, a zero-velocity updates (ZUPTs) methodology, as well as, a zero-velocity (ZV) detection algorithm. The novel approach presented in this dissertation uses the interactive multiple model (IMM) filter in order to determine the exact state of pedestrian with changing dynamics. This work evaluates the performance of the proposed method in two different ways: At first a vehicle traveling in a straight line is simulated using commonly used kinematic motion models in the area of tracking (constant velocity (CV), constant acceleration (CA) and coordinated turn (CT) models) which demonstrates accurate state estimation of targets with changing dynamics is achieved through the use of multiple model filter models. We conclude by proposing an interactive multiple model estimator based adaptive indoor pedestrian tracking system for handling dynamic motion which can incorporate different motion types (walking, running, sprinting and ladder climbing) whose threshold is determined individually and IMM adjusts itself adaptively to correct the change in motion models. Results indicate that the overall IMM performance will at all times be similar to the best individual filter model within the IMM

Smart Technology for Telerehabilitation: A Smart Device Inertial-sensing Method for Gait Analysis

The aim of this work was to develop and validate an iPod Touch (4th generation) as a potential ambulatory monitoring system for clinical and non-clinical gait analysis. This thesis comprises four interrelated studies, the first overviews the current available literature on wearable accelerometry-based technology (AT) able to assess mobility-related functional activities in subjects with neurological conditions in home and community settings. The second study focuses on the detection of time-accurate and robust gait features from a single inertial measurement unit (IMU) on the lower back, establishing a reference framework in the process. The third study presents a simple step length algorithm for straight-line walking and the fourth and final study addresses the accuracy of an iPod’s inertial-sensing capabilities, more specifically, the validity of an inertial-sensing method (integrated in an iPod) to obtain time-accurate vertical lower trunk displacement measures. The systematic review revealed that present research primarily focuses on the development of accurate methods able to identify and distinguish different functional activities. While these are important aims, much of the conducted work remains in laboratory environments, with relatively little research moving from the “bench to the bedside.” This review only identified a few studies that explored AT’s potential outside of laboratory settings, indicating that clinical and real-world research significantly lags behind its engineering counterpart. In addition, AT methods are largely based on machine-learning algorithms that rely on a feature selection process. However, extracted features depend on the signal output being measured, which is seldom described. It is, therefore, difficult to determine the accuracy of AT methods without characterizing gait signals first. Furthermore, much variability exists among approaches (including the numbers of body-fixed sensors and sensor locations) to obtain useful data to analyze human movement. From an end-user’s perspective, reducing the amount of sensors to one instrument that is attached to a single location on the body would greatly simplify the design and use of the system. With this in mind, the accuracy of formerly identified or gait events from a single IMU attached to the lower trunk was explored. The study’s analysis of the trunk’s vertical and anterior-posterior acceleration pattern (and of their integrands) demonstrates, that a combination of both signals may provide more nuanced information regarding a person’s gait cycle, ultimately permitting more clinically relevant gait features to be extracted. Going one step further, a modified step length algorithm based on a pendulum model of the swing leg was proposed. By incorporating the trunk’s anterior-posterior displacement, more accurate predictions of mean step length can be made in healthy subjects at self-selected walking speeds. Experimental results indicate that the proposed algorithm estimates step length with errors less than 3% (mean error of 0.80 ± 2.01cm). The performance of this algorithm, however, still needs to be verified for those suffering from gait disturbances. Having established a referential framework for the extraction of temporal gait parameters as well as an algorithm for step length estimations from one instrument attached to the lower trunk, the fourth and final study explored the inertial-sensing capabilities of an iPod Touch. With the help of Dr. Ian Sheret and Oxford Brookes’ spin-off company ‘Wildknowledge’, a smart application for the iPod Touch was developed. The study results demonstrate that the proposed inertial-sensing method can reliably derive lower trunk vertical displacement (intraclass correlations ranging from .80 to .96) with similar agreement measurement levels to those gathered by a conventional inertial sensor (small systematic error of 2.2mm and a typical error of 3mm). By incorporating the aforementioned methods, an iPod Touch can potentially serve as a novel ambulatory monitor system capable of assessing gait in clinical and non-clinical environments