Towards 'smart lasers': self-optimisation of an ultrafast pulse source using a genetic algorithm

Short-pulse fibre lasers are a complex dynamical system possessing a broad space of operating states that can be accessed through control of cavity parameters. Determination of target regimes is a multi-parameter global optimisation problem. Here, we report the implementation of a genetic algorithm to intelligently locate optimum parameters for stable single-pulse mode-locking in a Figure-8 fibre laser, and fully automate the system turn-on procedure. Stable ultrashort pulses are repeatably achieved by employing a compound fitness function that monitors both temporal and spectral output properties of the laser. Our method of encoding photonics expertise into an algorithm and applying machine-learning principles paves the way to self-optimising `smart' optical technologies

Bioinformatics framework for genotyping microarray data analysis

Functional genomics is a flourishing science enabled by recent technological breakthroughs in high-throughput instrumentation and microarray data analysis. Genotyping microarrays establish the genotypes of DNA sequences containing single nucleotide polymorphisms (SNPs), and can help biologists probe the functions of different genes and/or construct complex gene interaction networks. The enormous amount of data from these experiments makes it infeasible to perform manual processing to obtain accurate and reliable results in daily routines. Advanced algorithms as well as an integrated software toolkit are needed to help perform reliable and fast data analysis. The author developed a MatlabTM based software package, called TIMDA (a Toolkit for Integrated Genotyping Microarray Data Analysis), for fully automatic, accurate and reliable genotyping microarray data analysis. The author also developed new algorithms for image processing and genotype-calling. The modular design of TIMDA allows satisfactory extensibility and maintainability. TIMDA is open source (URL: http://timda.SF.net and can be easily customized by users to meet their particular needs. The quality and reproducibility of results in image processing and genotype-calling and the ease of customization indicate that TIMDA is a useful package for genomics research

Multi-Objective Optimization for Wind Estimation and Aircraft Model Identification

In this paper, a novel method for aerodynamic model identification of a micro-air vehicle is proposed. The principal contribution is a technique of wind estimation that provides information about the existing wind during flight when no air-data sensors are available. The estimation technique employs multi-objective optimization algorithms that utilize identification errors to propose the wind-speed components that best fit the dynamic behavior observed. Once the wind speed is estimated, the flight experimentation data are corrected and utilized to perform an identification of the aircraft model parameters. A multi-objective optimization algorithm is also used, but with the objective of estimating the aerodynamic stability and control derivatives. Employing data from different flights offers the possibility of obtaining sets of models that form the Pareto fronts. Deciding which model best adjusts to the experiments performed (compromise model) will be the ultimate task of the control engineer.The authors would like to thank the Spanish Ministry of Innovation and Science for providing funding through grant BES-2012-056210 and projects TIN-2011-28082 and ENE-25900. We also want to acknowledge the Generalitat Valenciana for financing this work through project PROMETEO/2012/028.Velasco Carrau, J.; García-Nieto Rodríguez, S.; Salcedo Romero De Ávila, JV.; Bishop, RH. (2015). Multi-Objective Optimization for Wind Estimation and Aircraft Model Identification. Journal of Guidance, Control, and Dynamics. 39(2):372-389. https://doi.org/10.2514/1.G001294S37238939

Key body pose detection and movement assessment of fitness performances

Motion segmentation plays an important role in human motion analysis. Understanding the intrinsic features of human activities represents a challenge for modern science. Current solutions usually involve computationally demanding processing and achieve the best results using expensive, intrusive motion capture devices. In this thesis, research has been carried out to develop a series of methods for affordable and effective human motion assessment in the context of stand-up physical exercises. The objective of the research was to tackle the needs for an autonomous system that could be deployed in nursing homes or elderly people's houses, as well as rehabilitation of high profile sport performers. Firstly, it has to be designed so that instructions on physical exercises, especially in the case of elderly people, can be delivered in an understandable way. Secondly, it has to deal with the problem that some individuals may find it difficult to keep up with the programme due to physical impediments. They may also be discouraged because the activities are not stimulating or the instructions are hard to follow. In this thesis, a series of methods for automatic assessment production, as a combination of worded feedback and motion visualisation, is presented. The methods comprise two major steps. First, a series of key body poses are identified upon a model built by a multi-class classifier from a set of frame-wise features extracted from the motion data. Second, motion alignment (or synchronisation) with a reference performance (the tutor) is established in order to produce a second assessment model. Numerical assessment, first, and textual feedback, after, are delivered to the user along with a 3D skeletal animation to enrich the assessment experience. This animation is produced after the demonstration of the expert is transformed to the current level of performance of the user, in order to help encourage them to engage with the programme. The key body pose identification stage follows a two-step approach: first, the principal components of the input motion data are calculated in order to reduce the dimensionality of the input. Then, candidates of key body poses are inferred using multi-class, supervised machine learning techniques from a set of training samples. Finally, cluster analysis is used to refine the result. Key body pose identification is guaranteed to be invariant to the repetitiveness and symmetry of the performance. Results show the effectiveness of the proposed approach by comparing it against Dynamic Time Warping and Hierarchical Aligned Cluster Analysis. The synchronisation sub-system takes advantage of the cyclic nature of the stretches that are part of the stand-up exercises subject to study in order to remove out-of-sequence identified key body poses (i.e., false positives). Two approaches are considered for performing cycle analysis: a sequential, trivial algorithm and a proposed Genetic Algorithm, with and without prior knowledge on cyclic sequence patterns. These two approaches are compared and the Genetic Algorithm with prior knowledge shows a lower rate of false positives, but also a higher false negative rate. The GAs are also evaluated with randomly generated periodic string sequences. The automatic assessment follows a similar approach to that of key body pose identification. A multi-class, multi-target machine learning classifier is trained with features extracted from previous motion alignment. The inferred numerical assessment levels (one per identified key body pose and involved body joint) are translated into human-understandable language via a highly-customisable, context-free grammar. Finally, visual feedback is produced in the form of a synchronised skeletal animation of both the user's performance and the tutor's. If the user's performance is well below a standard then an affine offset transformation of the skeletal motion data series to an in-between performance is performed, in order to prevent dis-encouragement from the user and still provide a reference for improvement. At the end of this thesis, a study of the limitations of the methods in real circumstances is explored. Issues like the gimbal lock in the angular motion data, lack of accuracy of the motion capture system and the escalation of the training set are discussed. Finally, some conclusions are drawn and future work is discussed

The Future of the Operating Room: Surgical Preplanning and Navigation using High Accuracy Ultra-Wideband Positioning and Advanced Bone Measurement

This dissertation embodies the diversity and creativity of my research, of which much has been peer-reviewed, published in archival quality journals, and presented nationally and internationally. Portions of the work described herein have been published in the fields of image processing, forensic anthropology, physical anthropology, biomedical engineering, clinical orthopedics, and microwave engineering. The problem studied is primarily that of developing the tools and technologies for a next-generation surgical navigation system. The discussion focuses on the underlying technologies of a novel microwave positioning subsystem and a bone analysis subsystem. The methodologies behind each of these technologies are presented in the context of the overall system with the salient results helping to elucidate the difficult facets of the problem. The microwave positioning system is currently the highest accuracy wireless ultra-wideband positioning system that can be found in the literature. The challenges in producing a system with these capabilities are many, and the research and development in solving these problems should further the art of high accuracy pulse-based positioning

Vision Science and Technology at NASA: Results of a Workshop

A broad review is given of vision science and technology within NASA. The subject is defined and its applications in both NASA and the nation at large are noted. A survey of current NASA efforts is given, noting strengths and weaknesses of the NASA program

Automated calibration of multi-sensor optical shape measurement system

A multi-sensor optical shape measurement system (SMS) based on the fringe projection method and temporal phase unwrapping has recently been commercialised as a result of its easy implementation, computer control using a spatial light modulator, and fast full-field measurement. The main advantage of a multi-sensor SMS is the ability to make measurements for 360° coverage without the requirement for mounting the measured component on translation and/or rotation stages. However, for greater acceptance in industry, issues relating to a user-friendly calibration of the multi-sensor SMS in an industrial environment for presentation of the measured data in a single coordinate system need to be addressed. The calibration of multi-sensor SMSs typically requires a calibration artefact, which consequently leads to significant user input for the processing of calibration data, in order to obtain the respective sensor's optimal imaging geometry parameters. The imaging geometry parameters provide a mapping from the acquired shape data to real world Cartesian coordinates. However, the process of obtaining optimal sensor imaging geometry parameters (which involves a nonlinear numerical optimization process known as bundle adjustment), requires labelling regions within each point cloud as belonging to known features of the calibration artefact. This thesis describes an automated calibration procedure which ensures that calibration data is processed through automated feature detection of the calibration artefact, artefact pose estimation, automated control point selection, and finally bundle adjustment itself. [Continues.