Building the case for actionable ethics in digital health research supported by artificial intelligence

The digital revolution is disrupting the ways in which health research is conducted, and subsequently, changing healthcare. Direct-to-consumer wellness products and mobile apps, pervasive sensor technologies and access to social network data offer exciting opportunities for researchers to passively observe and/or track patients ‘in the wild’ and 24/7. The volume of granular personal health data gathered using these technologies is unprecedented, and is increasingly leveraged to inform personalized health promotion and disease treatment interventions. The use of artificial intelligence in the health sector is also increasing. Although rich with potential, the digital health ecosystem presents new ethical challenges for those making decisions about the selection, testing, implementation and evaluation of technologies for use in healthcare. As the ‘Wild West’ of digital health research unfolds, it is important to recognize who is involved, and identify how each party can and should take responsibility to advance the ethical practices of this work. While not a comprehensive review, we describe the landscape, identify gaps to be addressed, and offer recommendations as to how stakeholders can and should take responsibility to advance socially responsible digital health research

Personalization-Privacy Paradox: Personal Health Information Context

While healthcare institutions continue to invest in personal health information (PHI) capabilities, consumers are increasingly becoming concerned about the use and storage of PHI. At the same time, consumers are increasingly becoming aware of the benefits that accrue from the use of PHI –i.e., the benefits of getting personalized healthcare. We use the Information Boundary Theory (IBT) to examine the effect of this tension–personalization-privacy paradox-on consumers’ willingness to share PHI. We contextualize the theoretical model by integrating the role of discrete contextual factors at play – trust in the electronic medium, information type, requesting stakeholder, and health status. In doing so, our research contributes to theory as well as practice. We expand and enrich the IBT by contextualizing it to the healthcare domain. The research contributes to practice by providing insights that can be used as a guide to craft healthcare IT implementation policy. Our/my research also addresses IS communities’ call for more research on consumer perspective

Application Of Blockchain Technology And Integration Of Differential Privacy: Issues In E-Health Domains

A systematic and comprehensive review of critical applications of Blockchain Technology with Differential Privacy integration lies within privacy and security enhancement. This paper aims to highlight the research issues in the e-Health domain (e.g., EMR) and to review the current research directions in Differential Privacy integration with Blockchain Technology.Firstly, the current state of concerns in the e-Health domain are identified as follows: (a) healthcare information poses a high level of security and privacy concerns due to its sensitivity; (b) due to vulnerabilities surrounding the healthcare system, a data breach is common and poses a risk for attack by an adversary; and (c) the current privacy and security apparatus needs further fortification. Secondly, Blockchain Technology (BT) is one of the approaches to address these privacy and security issues. The alternative solution is the integration of Differential Privacy (DP) with Blockchain Technology. Thirdly, collections of scientific journals and research papers, published between 2015 and 2022, from IEEE, Science Direct, Google Scholar, ACM, and PubMed on the e-Health domain approach are summarized in terms of security and privacy. The methodology uses a systematic mapping study (SMS) to identify and select relevant research papers and academic journals regarding DP and BT. With this understanding of the current privacy issues in EMR, this paper focuses on three categories: (a) e-Health Record Privacy, (b) Real-Time Health Data, and (c) Health Survey Data Protection. In this study, evidence exists to identify inherent issues and technical challenges associated with the integration of Differential Privacy and Blockchain Technology

Medical Informatics

Information technology has been revolutionizing the everyday life of the common man, while medical science has been making rapid strides in understanding disease mechanisms, developing diagnostic techniques and effecting successful treatment regimen, even for those cases which would have been classified as a poor prognosis a decade earlier. The confluence of information technology and biomedicine has brought into its ambit additional dimensions of computerized databases for patient conditions, revolutionizing the way health care and patient information is recorded, processed, interpreted and utilized for improving the quality of life. This book consists of seven chapters dealing with the three primary issues of medical information acquisition from a patient's and health care professional's perspective, translational approaches from a researcher's point of view, and finally the application potential as required by the clinicians/physician. The book covers modern issues in Information Technology, Bioinformatics Methods and Clinical Applications. The chapters describe the basic process of acquisition of information in a health system, recent technological developments in biomedicine and the realistic evaluation of medical informatics

LET\u27S GET PHYSIC(AI)L – TRANSFORMING AI-REQUIREMENTS OF HEALTHCARE INTO DESIGN PRINCIPLES

As healthcare\u27s digitization advances, artificial intelligence (AI) techniques offer opportunities to improve medical care. In addition to the much-discussed potential in diagnostics, AI-based systems can further support processes in clinics or comparable healthcare facilities, helping to improve medical, organizational, and administrative processes. Nevertheless, apart from single use-cases, AI in healthcare is still not unleashing its full potential. To empower the technology and provide a guideline for developers but also other entities such as medical institutions, we derive and plan to validate design principles guiding the design of AI-based systems specifically operating in clinics and healthcare facilities. In this research in progress study, we conduct the first two phases of the DSR approach by identifying requirements in literature and transforming these into design principles. By doing so, we provide a collection of literature-based design principles that need to be considered when implementing AI-based systems into healthcare contexts

Privacy-preserving scoring of tree ensembles : a novel framework for AI in healthcare

Machine Learning (ML) techniques now impact a wide variety of domains. Highly regulated industries such as healthcare and finance have stringent compliance and data governance policies around data sharing. Advances in secure multiparty computation (SMC) for privacy-preserving machine learning (PPML) can help transform these regulated industries by allowing ML computations over encrypted data with personally identifiable information (PII). Yet very little of SMC-based PPML has been put into practice so far. In this paper we present the very first framework for privacy-preserving classification of tree ensembles with application in healthcare. We first describe the underlying cryptographic protocols that enable a healthcare organization to send encrypted data securely to a ML scoring service and obtain encrypted class labels without the scoring service actually seeing that input in the clear. We then describe the deployment challenges we solved to integrate these protocols in a cloud based scalable risk-prediction platform with multiple ML models for healthcare AI. Included are system internals, and evaluations of our deployment for supporting physicians to drive better clinical outcomes in an accurate, scalable, and provably secure manner. To the best of our knowledge, this is the first such applied framework with SMC-based privacy-preserving machine learning for healthcare