Wireless neural/EMG telemetry system for freely moving insects

Journal ArticleWe have developed a miniature telemetry system that captures neural, EMG, and acceleration signals from a freely moving insect and transmits the data wirelessly to a remote digital receiver. The system is based on a custom low-power integrated circuit that amplifies and digitizes four biopotential signals as well as three acceleration signals from an off-chip MEMS accelerometer, and transmits this information over a wireless 920-MHz telemetry link. The unit weighs 0.79 g and runs for two hours on two small batteries. We have used this system to monitor neural and EMG signals in jumping and flying locusts

When Both Transmitting and Receiving Energies Matter: An Application of Network Coding in Wireless Body Area Networks

A network coding scheme for practical implementations of wireless body area networks is presented, with the objective of providing reliability under low-energy constraints. We propose a simple network layer protocol for star networks, adapting redundancy based on both transmission and reception energies for data and control packets, as well as channel conditions. Our numerical results show that even for small networks, the amount of energy reduction achievable can range from 29% to 87%, as the receiving energy per control packet increases from equal to much larger than the transmitting energy per data packet. The achievable gains increase as a) more nodes are added to the network, and/or b) the channels seen by different sensor nodes become more asymmetric.Comment: 10 pages, 7 figures, submitted to the NC-Pro Workshop at IFIP Networking Conference 2011, and to appear in the conference proceedings, published by Springer-Verlag, in the Lecture Notes in Computer Science (LNCS) serie

Ultra Wideband Impulse Radio Superregenerative Reception

Postprint (published version

A Sub-nW 2.4 GHz Transmitter for Low Data-Rate Sensing Applications

This paper presents the design of a narrowband transmitter and antenna system that achieves an average power consumption of 78 pW when operating at a duty-cycled data rate of 1 bps. Fabricated in a 0.18 μm CMOS process, the transmitter employs a direct-RF power oscillator topology where a loop antenna acts as a both a radiative and resonant element. The low-complexity single-stage architecture, in combination with aggressive power gating techniques and sizing optimizations, limited the standby power of the transmitter to only 39.7 pW at 0.8 V. Supporting both OOK and FSK modulations at 2.4 GHz, the transmitter consumed as low as 38 pJ/bit at an active-mode data rate of 5 Mbps. The loop antenna and integrated diodes were also used as part of a wireless power transfer receiver in order to kick-start the system power supply prior to energy harvesting operation.Semiconductor Research Corporation. Interconnect Focus CenterSemiconductor Research Corporation. C2S2 Focus CenterNational Institutes of Health (U.S.) (Grant K08 DC010419)National Institutes of Health (U.S.) (Grant T32 DC00038)Bertarelli Foundatio

A Miniature Animal-Computer Interface for Use with Free-Flying Moths

Although the neurophysiological basis of insect flight control has been studied extensively and successfully in animals attached to rigid tethers, these conditions disrupt the natural feedback between the subject's intentions, sensory input, and motor output. Understanding how individual control algorithms are integrated at a behavioral level requires acquisition and modification of biopotentials in completely untethered, free-flying animals. Herein, I present and test a miniaturized animal-computer interface for use with freely-flying Manduca sexta hawkmoths. This device is capable of simultaneously acquiring two independent biopotential signals, applying electrical neuromuscular stimulation, and correlating collected and applied signals with behavioral data from high-speed videography. Application of this device may offer substantial insight into how insects fly and, by replicating these mechanisms, facilitate wider application of micro air vehicles through improved flight efficiency, stability, and maneuverability

UWB Analog Multiplier in 90nm CMOS SoC Pulse Radar Sensor for Biomedical Applications

This thesis reports the description and results of the doctoral research programme in Information Engineering (University of Pisa), carried out in the three years from 2008 to 2010. The doctoral research programme has been originated by the European project ProeTEX aimed at developing a new generation of equipments for the market of emergency operators, like fire-fighters and Civil Protection rescuers. In this context, the multidisciplinary research group originated by the international cooperation of the research groups led by Prof. Danilo De Rossi (University of Pisa, Italy) as for Bio-engineering and Dr. Domenico Zito (University College Cork and Tyndall National Institute, Cork, Ireland) as for Microelectronics, has focused on the implementation of an innovative ultra-wide-band (UWB) pulse radar sensor fully integrated on a single silicon die for non-invasive and contact-less cardio-pulmonary monitoring within a wearable textile sensor platform. The radar sensor is designed to detect the heart and respiratory rates, which can be transmitted to a personal server that coordinates the entire Wireless Body Area Network (WBAN). Such radar sensor should sense the mechanical activity instead of the electrical activity of the heart. UWB bio-sensing allows low risk preliminary monitoring without discomfort since the radar system permits continuous monitoring without requiring any contact with the skin of the patient unlike the traditional technologies (i.e. ultrasounds). In detail, the radar transmits a sequence of extremely short electromagnetic pulses towards the heart and, due to the capability of microwaves to penetrate body tissues, detects the heart wall movement by correlating the echoes reflected with local replicas of the transmitted pulses properly delayed (i.e. time of flight). The specific aim of the doctoral research program has been the design and experimental characterization of the CMOS UWB analog multiplier, which is a crucial circuit in the receiver chain that implements the correlation between the received and amplified echo and the local replica, generated on-chip, of the transmitted pulse. The fully-differential circuit consists of a p-MOSFET common-gate differential pair as input stage for a wideband impedance matching, a p-MOSFET Gilbert’s quad as multiplier stage, and active loads. The circuit has been designed and fabricated in 90nm CMOS. Given the few works on similar analog circuits having inferior performance with respect to those requested, an innovative circuit solution has been identified. Moreover, a novel time-domain metric has been introduced in order to put in evidence the real behaviour of the system that differs from a traditional mixer commonly analyzed using frequency-domain metrics. This new metric, namely Input-Output Energy Ratio (IOER), aims at the optimization of the multiplier circuit design so that the output voltage corresponding to maximum correlation between two input pulses is maximized. The experimental characterization and the comparison with the state of the art have shown that the multiplier exhibits one of the best set of performance available in literature. The novel multiplier has been co-integrated with the other building blocks of the radar. The preliminary experimental characterization of the test-chips carried out by the research group, has demonstrated that the proposed UWB radar sensor works properly. It can detect a reflective target consisting of a half-centimetre-thick board surface (26×26 cm2) covered by aluminium foil, up to a distance of 70 cm. Moreover, it can detect the respiratory rate of a person placed at a distance of 25 cm. This work presents the first implementation, including experimental evidences, of a SoC UWB pulse radar front-end based on a correlation receiver, in 90nm CMOS technology

Multi-channel ultra-low-power receiver architecture for body area networks

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 85-91).In recently published integrated medical monitoring systems, a common thread is the high power consumption of the radio compared to the other system components. This observation is indicative of a natural place to attempt a reduction in system power. Narrowband receivers in-particular can enjoy significant power reduction by employing high-Q bulk acoustic resonators as channel select filters directly at RF, allowing down-stream analog processing to be simplified, resulting in better energy efficiency. But for communications in the ISM bands, it is important to employ multiple frequency channels to permit frequency-division-multiplexing and provide frequency diversity in the face of narrowband interferers. The high-Q nature of the resonators means that frequency tuning to other channels in the same band is nearly impossible; hence, a new architecture is required to address this challenge. A multi-channel ultra-low power OOK receiver for Body Area Networks (BANs) has been designed and tested. The receiver multiplexes three Film Bulk Acoustic Resonators (FBARs) to provide three channels of frequency discrimination, while at the same time offering competitive sensitivity and superior energy efficiency in this class of BAN receivers. The high-Q parallel resonance of each resonator determines the passband. The resonator's Q is on the order of 1000 and its center frequency is approximately 2.5 GHz, resulting in a -3 dB bandwidth of roughly 2.5 MHz with a very steep rolloff. Channels are selected by enabling the corresponding LNA and mixer pathway with switches, but a key benefit of this architecture is that the switches are not in series with the resonator and do not de-Q the resonance. The measured 1E-3 sensitivity is -64 dBm at 1 Mbps for an energy efficiency of 180 pJ/bit. The resonators are packaged beside the CMOS using wirebonds for the prototype.by Phillip Michel Nadeau.S.M

Noise and Blocker Cancellation Techniques for Power and Area Efficient Wireless Receivers

The design of mobile wireless devices has always focused on reducing power, area, and cost. This dissertation proposes two techniques that are leveraged to save power and area and therefore cost. The first techniques reduces the noise in the receiver and results in a relaxed power requirement. The second technique filters the blocker on-chip and allows for the removal of bulky off-chip components in a wireless system. In the first technique a two-path noise-cancellation architecture is used that reduces the noise in the receiver front end. A prototype ultra-wideband (UWB) receiver is designed and fabricated based on this idea in a 130 nm CMOS process. The fabricated prototype achieves an energy efficiency of 0.48 nJ/bit with a sensitivity of -82 dBm while operating across a wide data rate range of 0.1-25 Mb/s. The second technique is a blocker filtering scheme that extracts the clock from the blocker and helps eliminate bulky off-chip surface acoustic wave (SAW) filter components. Implemented in a 65 nm CMOS process, the filter is able to track the blocker within 1 to 1.6 GHz and provides better than 10 dB of rejection at the notch frequency for blockers from -40 dBm to -10 dBm

Doctor of Philosophy

dissertationSince the late 1950s, scientists have been working toward realizing implantable devices that would directly monitor or even control the human body's internal activities. Sophisticated microsystems are used to improve our understanding of internal biological processes in animals and humans. The diversity of biomedical research dictates that microsystems must be developed and customized specifically for each new application. For advanced long-term experiments, a custom designed system-on-chip (SoC) is usually necessary to meet desired specifications. Custom SoCs, however, are often prohibitively expensive, preventing many new ideas from being explored. In this work, we have identified a set of sensors that are frequently used in biomedical research and developed a single-chip integrated microsystem that offers the most commonly used sensor interfaces, high computational power, and which requires minimum external components to operate. Included peripherals can also drive chemical reactions by setting the appropriate voltages or currents across electrodes. The SoC is highly modular and well suited for prototyping in and ex vivo experimental devices. The system runs from a primary or secondary battery that can be recharged via two inductively coupled coils. The SoC includes a 16-bit microprocessor with 32 kB of on chip SRAM. The digital core consumes 350 μW at 10 MHz and is capable of running at frequencies up to 200 MHz. The integrated microsystem has been fabricated in a 65 nm CMOS technology and the silicon has been fully tested. Integrated peripherals include two sigma-delta analog-to-digital converters, two 10-bit digital-to-analog converters, and a sleep mode timer. The system also includes a wireless ultra-wideband (UWB) transmitter. The fullydigital transmitter implementation occupies 68 x 68 μm2 of silicon area, consumes 0.72 μW static power, and achieves an energy efficiency of 19 pJ/pulse at 200 MHz pulse repetition frequency. An investigation of the suitability of the UWB technology for neural recording systems is also presented. Experimental data capturing the UWB signal transmission through an animal head are presented and a statistical model for large-scale signal fading is developed