High-performance Diagnosis of Sleep Disorders: A Novel, Accurate and Fast Machine Learning Approach Using Electroencephalographic Data

While diagnosing sleep disorders by physicians using electroencephalographic data is protracted and inaccurate, we report promising results from a novel, fast and reliable machine learning approach. Our approach only needs an electroencephalographic recording snippet of 10 minutes instead of eight hours to correctly classify the disorder with an accuracy of over 90 percent. The Rapid Eye Movement sleep behavior disorder can lead to secondary diseases like Parkinson or Dementia. Therefore, it is important to classify the disorder fast and with a high level of accuracy - which is now possible with our approach

Development of a Machine Learning Based Algorithm To Accurately Detect Schizophrenia based on One-minute EEG Recordings

While diagnosing schizophrenia by physicians based on patients' history and their overall mental health is inaccurate, we report on promising results using a novel, fast and reliable machine learning approach based on electroencephalography (EEG) recordings. We show that a fine granular division of EEG spectra in combination with the Random Forest classifier allows a distinction to be made between paranoid schizophrenic (ICD-10 F20.0) and non-schizophrenic persons with a very good balanced accuracy of 96.77 percent. We evaluate our approach on EEG data from an open neurological and psychiatric repository containing 499 one-minute recordings of n=28 participants (14 paranoid schizophrenic and 14 healthy controls). Since the fact that neither diagnostic tests nor biomarkers are available yet to diagnose paranoid schizophrenia, our approach paves the way to a quick and reliable diagnosis with a high accuracy. Furthermore, interesting insights about the most predictive subbands were gained by analyzing the electroencephalographic spectrum up to 100 Hz

Machine Learning Based Diagnostics of Developmental Coordination Disorder using Electroencephalographic Data

We report on promising results concerning the fast and accurate diagnosis of developmental coordination disorder (DCD) which heavily impacts the life of affected children with emotional and behavioral issues. Using a machine learning classifier on spectral data of electroencephalography (EEG) recordings and unfolding the traditional frequency bandwidth in a fine-graded equidistant 99-point spectrum we were able to reach an accuracy of over 99.35 percent having only one misclassification. Our machine learning work contributes to healthcare and information systems research. While current diagnostic methods in use are either complicated, time-consuming, or inaccurate, our automated machine-based approach is accurate and reliable. Our results also provide more insights into the relationship between DCD and brain activity which could stimulate future work in medicine

A novel approach in discovering significant interactions from TCM patient prescription data

The efficacy of a traditional Chinese medicine medication derives from the complex interactions of herbs or Chinese Materia Medica in a formula. The aim of this paper is to propose a new approach to systematically generate combinations of interacting herbs that might lead to good outcome. Our approach was tested on a data set of prescriptions for diabetic patients to verify the effectiveness of detected combinations of herbs. This approach is able to detect effective higher orders of herb-herb interactions with statistical validation. We present an exploratory analysis of clinical records using a pattern mining approach called Interaction Rules Mining

A novel approach in discovering significant interactions from TCM patient prescription data

The efficacy of a traditional Chinese medicine medication derives from the complex interactions of herbs or Chinese Materia Medica in a formula. The aim of this paper is to propose a new approach to systematically generate combinations of interacting herbs that might lead to good outcome. Our approach was tested on a data set of prescriptions for diabetic patients to verify the effectiveness of detected combinations of herbs. This approach is able to detect effective higher orders of herb-herb interactions with statistical validation. We present an exploratory analysis of clinical records using a pattern mining approach called Interaction Rules Mining