DReAM: An approach to estimate per-Task DRAM energy in multicore systems

Accurate per-task energy estimation in multicore systems would allow performing per-task energy-aware task scheduling and energy-aware billing in data centers, among other applications. Per-task energy estimation is challenged by the interaction between tasks in shared resources, which impacts tasks’ energy consumption in uncontrolled ways. Some accurate mechanisms have been devised recently to estimate per-task energy consumed on-chip in multicores, but there is a lack of such mechanisms for DRAM memories. This article makes the case for accurate per-task DRAM energy metering in multicores, which opens new paths to energy/performance optimizations. In particular, the contributions of this article are (i) an ideal per-task energy metering model for DRAM memories; (ii) DReAM, an accurate yet low cost implementation of the ideal model (less than 5% accuracy error when 16 tasks share memory); and (iii) a comparison with standard methods (even distribution and access-count based) proving that DReAM is much more accurate than these other methods.Peer ReviewedPostprint (author's final draft

Analysis, classification and comparison of scheduling techniques for software transactional memories

Transactional Memory (TM) is a practical programming paradigm for developing concurrent applications. Performance is a critical factor for TM implementations, and various studies demonstrated that specialised transaction/thread scheduling support is essential for implementing performance-effective TM systems. After one decade of research, this article reviews the wide variety of scheduling techniques proposed for Software Transactional Memories. Based on peculiarities and differences of the adopted scheduling strategies, we propose a classification of the existing techniques, and we discuss the specific characteristics of each technique. Also, we analyse the results of previous evaluation and comparison studies, and we present the results of a new experimental study encompassing techniques based on different scheduling strategies. Finally, we identify potential strengths and weaknesses of the different techniques, as well as the issues that require to be further investigated

High-throughput Binding Affinity Calculations at Extreme Scales

Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolutionarily selected during treatment. Key to overcoming this challenge is an understanding of the molecular determinants of drug binding. Using multi-stage pipelines of molecular simulations we can gain insights into the binding free energy and the residence time of a ligand, which can inform both stratified and personal treatment regimes and drug development. To support the scalable, adaptive and automated calculation of the binding free energy on high-performance computing resources, we introduce the High- throughput Binding Affinity Calculator (HTBAC). HTBAC uses a building block approach in order to attain both workflow flexibility and performance. We demonstrate close to perfect weak scaling to hundreds of concurrent multi-stage binding affinity calculation pipelines. This permits a rapid time-to-solution that is essentially invariant of the calculation protocol, size of candidate ligands and number of ensemble simulations. As such, HTBAC advances the state of the art of binding affinity calculations and protocols

DReAM: Per-task DRAM energy metering in multicore systems

Interaction across applications in DRAM memory impacts its energy consumption. This paper makes the case for accurate per-task DRAM energy metering in multicores, which opens new paths to energy/performance optimizations, such as per-task energy-aware task scheduling and energy-aware billing in datacenters. In particular, the contributions of this paper are (i) an ideal per-task energy metering model for DRAM memories; (ii) DReAM, an accurate, yet low cost, implementation of the ideal model (less than 5% accuracy error when 16 tasks share memory); and (iii) a comparison with standard methods (even distribution and access-count based) proving that DReAM is more accurate than these other methods.This work has been partially supported by the Spanish Ministry of Science and Innovation under grant TIN2012-34557, the HiPEAC Network of Excellence, by the European Research Council under the European Union’s 7th FP, ERC Grant Agreement n. 321253, and by a joint study agreement between IBM and BSC (number W1361154). Qixiao Liu has also been funded by the Chinese Scholarship Council under grant 2010608015.Postprint (published version