74,331 research outputs found
Reactivity on the Web
Reactivity, the ability to detect simple and composite events and respond in a timely
manner, is an essential requirement in many present-day information systems. With
the emergence of new, dynamic Web applications, reactivity on the Web is receiving
increasing attention. Reactive Web-based systems need to detect and react not only
to simple events but also to complex, real-life situations. This paper introduces
XChange, a language for programming reactive behaviour on the Web, emphasising
the querying of event data and detection of composite events
Estimating the relative rate of recombination to mutation in bacteria from single-locus variants using composite likelihood methods
A number of studies have suggested using comparisons between DNA sequences of
closely related bacterial isolates to estimate the relative rate of
recombination to mutation for that bacterial species. We consider such an
approach which uses single-locus variants: pairs of isolates whose DNA differ
at a single gene locus. One way of deriving point estimates for the relative
rate of recombination to mutation from such data is to use composite likelihood
methods. We extend recent work in this area so as to be able to construct
confidence intervals for our estimates, without needing to resort to
computationally-intensive bootstrap procedures, and to develop a test for
whether the relative rate varies across loci. Both our test and method for
constructing confidence intervals are obtained by modeling the dependence
structure in the data, and then applying asymptotic theory regarding the
distribution of estimators obtained using a composite likelihood. We applied
these methods to multi-locus sequence typing (MLST) data from eight bacteria,
finding strong evidence for considerable rate variation in three of these:
Bacillus cereus, Enterococcus faecium and Klebsiella pneumoniae.Comment: Published at http://dx.doi.org/10.1214/14-AOAS795 in the Annals of
Applied Statistics (http://www.imstat.org/aoas/) by the Institute of
Mathematical Statistics (http://www.imstat.org
Use-cases on evolution
This report presents a set of use cases for evolution and reactivity for data in the Web and
Semantic Web. This set is organized around three different case study scenarios, each of them
is related to one of the three different areas of application within Rewerse. Namely, the scenarios
are: “The Rewerse Information System and Portal”, closely related to the work of A3
– Personalised Information Systems; “Organizing Travels”, that may be related to the work
of A1 – Events, Time, and Locations; “Updates and evolution in bioinformatics data sources”
related to the work of A2 – Towards a Bioinformatics Web
A Parameterized Algebra for Event Notification Services
Event notification services are used in various applications such as digital libraries, stock tickers, traffic control, or facility management. However, to our knowledge, a common semantics of events in event notification services has not been defined so far. In this paper, we propose a parameterized event algebra which describes the semantics of composite events for event notification systems. The parameters serve as a basis for flexible handling of duplicates in both primitive and composite events
Near-Infrared Microlensing of Stars by the Super-Massive Black Hole in the Galactic Center
We investigate microlensing amplification of faint stars in the dense stellar
cluster in the Galactic Center (GC) by the super-massive black hole (BH). Such
events would appear very close to the position of the radio source SgrA*, which
is thought to coincide with the BH, and could be observed during the monitoring
of stellar motions in the GC. We use the observed K-band (2.2 um) luminosity
function (KLF) in the GC and in Baade's Window, as well as stellar population
synthesis computations, to construct KLF models for the inner 300 pc of the
Galaxy. These, and the observed dynamical properties of this region, are used
to compute the rates of microlensing events, which amplify stars above
specified detection thresholds. We present computations of the lensing rates
and amplifications as functions of the event durations (weeks to years), for a
range of detection thresholds. We find that short events dominate the total
rate and that long events tend to have large amplifications. For the current
detection limit of K=17 mag, the total microlensing rate is 0.003 1/yr, and the
rate of events with durations >1 yr is 0.001 1/yr. Recent GC proper motion
studies have revealed the possible presence of one or two variable K-band
sources very close to SgrA* (Genzel et al 97; Ghez et al 98). These sources may
have attained peak brightnesses of K~15 mag, about 1.5-2 mag above the
observational detection limits, and appear to have varied on a timescale of ~1
yr. This behavior is consistent with long-duration microlensing of faint stars
by the BH. However, we estimate that the probability that such an event could
have been detected during the course of the recent proper motion studies is
\~0.5%. A ten-fold improvement in the detection limit and 10 yr of monthly
monitoring would increase the total detection probability to ~20%. (Abridged)Comment: 29 p. with 5 figs. To appear in ApJ. Changed to reflect published
version. Short discussions of solar metallicity luminosity function and
star-star microlensing adde
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